HsaINT0126133 @ hg38
Intron Retention
Gene
ENSG00000123143 | PKN1
Description
protein kinase N1 [Source:HGNC Symbol;Acc:HGNC:9405]
Coordinates
chr19:14451829-14458140:+
Coord C1 exon
chr19:14451829-14452023
Coord A exon
chr19:14452024-14458030
Coord C2 exon
chr19:14458031-14458140
Length
6007 bp
Sequences
Splice sites
5' ss Seq
CCAGTGAGT
5' ss Score
8.28
3' ss Seq
GGCCCTCTCTCCCATTTCAGGTG
3' ss Score
12.83
Exon sequences
Seq C1 exon
GGACCCTGGAGGTACGAGTGGTGGGCTGCAGAGACCTCCCAGAGACCATCCCGTGGAACCCTACCCCCTCAATGGGGGGACCTGGGACCCCAGACAGCCGCCCCCCCTTCCTGAGCCGCCCAGCCCGGGGCCTTTACAGCCGAAGCGGAAGCCTCAGTGGCCGGAGCAGCCTCAAAGCAGAAGCCGAGAACACCA
Seq A exon
GTGAGTGGGCATCGTGGGCCCTGAGAAACGAGGTGGCATTGGGGACCTGGAATGCCCCATATTTGTAAACCTTTAAAAAATAAGCCAGGGGTCGGGTGTGGTGGCTCACACATGTAATCCCAGCACTTTGGGAAGCCAAGGTGGACGGATCACTTGAGGTCAGGAATTTGAGACCAGCCTGGCCAACATGGTGAAACACTGTCTCTACTTAAAAATACAACTTAGCTGGGCATGGTGGTGCACACCTGTAATCCCAGCTGTTTGGGAGGCTTAGGCAGGAGAATTACTTGAACCCGGGAGGTGGAAATTGCAGTGAGCCATGATCACGCCATTGCCCTCCAGCCTGGGTGACAGAGTGAGACTTTGCCTCAAAAGAGAACGAAAACAACAACAAAAACAAAAAAACAGGCCAGGTGCAGCAGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGACAGGAGGATCACTTGAGGCCAGGAGTTTGAGACCAGCCTGGGCAACATAGCAAGACCCTGTCTCTACAAAAAATAAAATGTAAAAATTAGCCAGATGTGGTGGCCCACACCTGTAGTCCTAGCTGTTCTAGAGGTGGGAGGATCACTTGAGCCCAGTGAGCTATCATTGAGCCATTTCACTCTAGCCTAGATGACAGAGAGACCCTGTCTCTAAATTAAAAAAAAAGAAAAAAAACTTCAAGTTTATTTAGATTAAAAAAAAGGCTGGGCGTGGTGGCTCACGCCTGTAATCCCAGCACTTGGGGAGGCCGAGGCGGGTGGATCACGAGGTCAGGAGTTCAAGACCAGCCTGGCCAGCATGGTGAAACCCCATCTCTACAAAAAATACAAAAAAATTAGCCAGGCGTGGCGGCGCGTGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGAGAATTGCTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCCGCGATTGTGCCACCGTACTCCAGCCTGTGCAACAGAGCAAGACTCCATCTCAAAATAATAATAATAATAATAAATAAATAAAACAAATTTAAAAAGAAAGGAAAACCAAACAAGAAACCAATATATCATATTCATTAGGATGACTAATACTATTTTAAAAACCCAACAAAACAAACAGAAAATAAGTGTTGGTGAGGATGTGGAGAGAAATCAGAACCTTTGTGCACTGTTGGTGGGAATGTAAAATGGTGCAGCCCTATGGAAAATATATTGGCATGGCCGGGTGCAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAGGGGGCCAGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCTATCATGGCAAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGGCATGGTGGTGTGTGTCTGTAATCCCAGCTACTCAGAAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGCAGAAGTTGCAGTGAGCTTAGATCGAGCCACTGCACTCCAGCCTGGGCAACAGAGCGAGACTCTGTCTGAAAGAAAGAGAGAGAGAGGGAGGGAGGGAGGGAGGAAGGAATATTGGCAGTTCCTGAAACAAGTAAAAACAGAGTAAGCAGTCCAGGCGCAATGGCTCACACCTGTAATTCCACCACTTTGGGAGGTCAAGGTAGGTGGATCACCTGAGGTCAGAAGTTCAAGACCAGCCTGGCCATCATGGTGAAACCCCATTTCTACTAAAAATACAAAAGTTAACCGGGCTTGGTGGTGGTGCACGCCTGTAGTCCCAGCTACTCTGGAGGCTGAGGCAGGAGAATTGCTTGAATCCGGGAGGCAGAGGTTGGAGTGAGCAGAGATCATGCTACTGCACTCCAGCCTGGGTGACAGAATGAGACTCCATCTCAAAACAAACAAACAAACAAAAAAACAAGAGTAACCATATGATCCAAAGCTACTTCTGGGCATATCCCCAAAAGAATTAAAAACAGGGCCTCGGACATTCCATAATGCATACATATTTCAAAACAACATGTTGTGCATGATAAATATATATAATTTTTATTTGTCAGTTTTAAAAATAGTGATAGAAAAATATTTAAAAAAAAAAAAAAGGGTCTCAGAGATATGTATACCTGTGTTCATAGCAGCATTATGAAAGCCAAAAATGGAAGCAACCCAGATCCACCAATAGATGAATGGGTAAACAAAACGTGGGCCAGCCATGCAATGGAACATTGCTCAGATTTAAAAAGGAAAGAAATCCTGCCAGGCGCAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACTTGAGGTCAGGGGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTATTAAAAATACAAAAATTAGCCGGGTGTGGTGGCACATGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGTAGGAAAACCGCTTGAGCCCAGGAGGCAGGCGTTGCAGTCAGCCAAGATCATGCCACCGCACTCCTGCCTGGGTGACAGAGTGAAACACTGTCTCAAAAAAAAAAAAAAAAAAAAGGAAAGGAATCCTGTCTTATCCTGCAACACGGATGAATCTTGAGGACATTAGTCTAAGTGAAATAAGCCAGTCCCCAAAAGACAAATATTGTATGATTCCAGTTATATGAGGTTCCTAGAGTAGTTAGATTCATAGAGACAGAAAGTAGAATGATGGATGCCAGGGAGTAGAGGGAGGGGGAATGGGGAGTTTATTATTTAATGTGGACAGAGTTTCAGTTTTGTAAGGTGAAAGTTCTGGAGATGGATGGTGGTAATGGTTGCACAGCAATGTGAATGTACTTAATGCCACTGAACTGGATGGACACTTTAAAGTGATTATGATGGTAAATTTTATGTTACATGTATTTTACCATAATTTTTTTTTTCTTGAGACAGATTCTCCTCTGCTGCCCAGGCTGGAGTGCAGTGGCACCGTCTCAGCTCACTGCAACCTCTGCCTCCTCGGTTTGAGCGATTCTCTTGCCTCAGCCAACCCAAATAGCTGGTGGGATTACAGGCGTGCGCCACCACACCCGGCTAATTTTTGTATTTTTATGGAGATGGGGTTTCACCATGTTGGCCATAATTTTTTTAAAAGAAAATTTGATTCGTAATCTCATGGCAAAAAAGGAAAAAGAAAGAAAATTAATACGTATGTACAAAAAAAAAAGGGAGTGTGGAGAAGAGTAACAGGAGAGCAGACACCCATATTACCACCACCTGCGTTAGGAAATAGAATATGGCAGCCAGGTGCCACGGCTCATGCCTGGAATCCCAGCATTTTGGTATTTGTAGGAGGATCACTTGAACCCAGGAGTTCAAGACCAGCCTGGGCAACATAGCAAGACCTTGTCTTTACAAATAATTTAAAAATTGGGGCATATGGCCAGGTGTGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAAGCGGGTGGATCACAAGGTCAGGAGATCGAGACCATCCTGGCTAACACAGTGAAACCCCAACTCTACTAAAAATACAAACAATTAGCCAGGCGTGGTGGTGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAGTGGCATGAACCTGGGAGGCAGAGCTTGCAGTGAGCCGAGATCGCGCCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCTGTCTCAAAAAAAAAAAAAATTGGGGGTACATGTCATCAGGCCCTCCTGAATCTGTGTCACAGAAAAAAAAACTAAAGGGAAAAAAAGAGAAGACAAGCCAACCAAAAATTAACCAGGCGTGGGCATGGTGGCTTGTGCCTGCGGTCCCAGCTACTTGGGAGGCTGAAGTGGGAGGATTGCTTGAGCGCAGGAGGTCAAGGCTACAGTGAGCTGTGATTGCACCACTGCATTCCAGCCTGGGCAACTGAGCGAGACCCCATCTTAAAAAAAAAAAAAAAGGAAAAGAAATAGAATATTTCCAGCTCTCCAGAAGCCCCCTCTTGTCTCCTCCACAATTCCATCTCCTTCCTCTGCCATAGAGGTGGCTACTCTCCCGACTTTTATCATTTCCTTGCTATAATTTGTAGTTGTAGAACCCCATGTTTGCATCCCCAAAAACTTTTGTTTAATTTTGCCTGGTATTAGAACTTTATATTGACAGGCTCATACAGACTATTCTATCACATGGCTTCTTTCATTCAACATTGTTTAGGGGCTAGGCATAGTGGCTCATGCCTGTAATCCCAGCACTTTGAGAGGCCGAGGTGGAGGGATTGCTTGAGCCAAGGAATTTGAACCCAGCCTGGGCAACATGGTGAAACCCCACCCTACAAAAAAATGCAAAAAACAAAACCAAACTAAAAAAAGCATTGTTTTGGTAGACTCATCCATTTTGTTGTGACAAGCTATAGTTAATTCATATTTATTCCTGTTTAGTAATCCATTATGTTAGACTGAGCCATATCGAATTGCCTCTTTCTGAAAGCAAAAAAATAGTTAAATATCAGCAATTTCGTACTTCAGCTACTAAGATGGTATAGCAGTTTTAAAATATTAATTCTCCTGTTAATGGACTGTGGGATGCCTCTATTTTGGACTGTTACATACACTTTATATAAATGCATCTCCTGATGTATACCCACATGCATTTGGCTAGGGTAAATCCTCAGGAGTGCCTGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGAGAAGCCAAGACCAGTGATCACTTGAGGTCAGGAGTTCAAGACCATCCTGGCCAACGTGGCAAAACCCCATCTCTACTAAAAACACAAAAATTAGCTGGGCATGGTGGTGTGCGCCTGTAGTCTGAGCTACTTTGGAAGCTGAGGCACGAGAATTGTTTGAACCCAGAAGGTGGAAGTTGCAGTGAGCCGAGATTGTGCCACTGCACTCCATCCTGGGTGACAGAGAGAGACTCTGGCTCAAAAAATAAATGAATAAATAAATCCTTAGGAGTATGTGGCTGGGACTTCCATGTAGAATAAAATTGAATTTGGATCCCTGCCTCACATCACACCATGTAAAAAAATCAACTGGATTAAAGGCTTCAATGTCAAATGCAAAACTTTACAGTGGGAGAAAAGTTATGGAGGGGAGGATTCATTTTAAAAAGATAGCAGACAGCTAGGCCTGGTGGCTCATGCCTGTAATCCCAGATACTTGGGAGGCTGAGGCAGGAGAATATCACTTGAGGCCAGGAGTTTGAGACCAGCCTGGGCAACATAACAAGACTCATCTCTACTGAAAAAAAAAAAAAAAAAGAAAAAGATAATAGACATGCCCCTTTCTGCCAGGATTTTCTTTCTTTTTCTTTTTTTTTTTTCTTTTTTTTTTTTTTTGAGATGGAGCTTCACTCTTGTTGCCCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGGGATTCTCCTGCCTCAGCCTCCCGAGTAACTGGGATTACAGGCATGTGCAACCACGCCTGGGTAATTTTTTATTTTTAGTAGACATGGGGTTTCACCATGTTGGTCAGGCTGGTCTCAAACTTCTGACCTCAGGTGATCCACCTGCCTCAGCCTCCGAAAGTGTTGAGATTACAGGCATGAGCCACTGTGCCTGGCCGTTTTTATTTTCTCTTCTCTTCTCTTCTCTCTTTTCGACCGAGTCTTGCTGTGTCACGCAGGCTGGAGCGCAGTAGCACGATCTTGGCTCACTACAACCTCTGCCTCCTGGGTTCAAGTGATTCTCCTTCCTCAGCCTCCCGAGTAGCTGGCATTACAGGCGCGTGCCACCACGCCCAGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCGCTATGATGGCCAGGCTGGTCTTGAACTCCTGGCCTCAAGTGATCGCCTGCCTCAACCTCCTAAAGTGCCGGGATTACAGGCATGAGCAACCTTGTCTGGCTACTGCCAGCATTTTCTGACTGGGCCCTCTCTCCCATTTCAG
Seq C2 exon
GTGAAGTCAGCACTGTGCTTAAGCTGGATAACACAGTGGTGGGGCAGACGTCTTGGAAGCCATGTGGCCCCAATGCCTGGGACCAGAGCTTCACTCTGGAGCTGGAAAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000123143:ENST00000242783:7
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.515 A=NA C2=0.152
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development