HsaINT0133028 @ hg38
Intron Retention
Gene
ENSG00000151006 | PRSS53
Description
protease, serine 53 [Source:HGNC Symbol;Acc:HGNC:34407]
Coordinates
chr16:31085110-31086183:-
Coord C1 exon
chr16:31085964-31086183
Coord A exon
chr16:31085261-31085963
Coord C2 exon
chr16:31085110-31085260
Length
703 bp
Sequences
Splice sites
5' ss Seq
TAGGTACGA
5' ss Score
7.12
3' ss Seq
GAGGCACTTATCTGTTTCAGCCT
3' ss Score
4.23
Exon sequences
Seq C1 exon
GGAGATTCCGGGGGCCCTGTGCTGTGCCTCGAGCCTGACGGACACTGGGTTCAGGCTGGCATCATCAGCTTTGCATCAAGCTGTGCCCAGGAGGACGCTCCTGTGCTGCTGACCAACACAGCTGCTCACAGTTCCTGGCTGCAGGCTCGAGTTCAGGGGGCAGCTTTCCTGGCCCAGAGCCCAGAGACCCCGGAGATGAGTGATGAGGACAGCTGTGTAG
Seq A exon
GTACGAGTGGGGCATGCTGGGAGTGGGCAGAAGCCACTGTGAAGCAAACCTCAGTTAGGACTAGAGAACTGGCATAGGCATCCACACCGCCGAGCCTAATTAGGGGGCTCTTTCACCCCCTGGGATGGGAACAGCCCTGTTAGGGCTGAGAGGCACAGGCACTTTGGAACTCTACAGGTTTGGAGTTTAGGTGAGAAGAGGAATCTCTGAGACCTGACTTGGGTTTCTGGGGAAGTGGCAGGCTTCCAGCAGGGACCCAGCGAGCCTGCACAGGGTAGGGCTCCCAGTCAGAATTCCGGCATTAAGTGACTGGCATGCAAATTGAATGCAAAGTAATTCCTGGGACGGATATTATGTCTTGATGATAAGAGATGCACTAATGAGTCAGGAATACGGGAGGCAGGCCCATCCTGGAGGGTGCAGACGGGTGGAGCAGGGGAGTGACAAGTAGGGGCATTCCCACGAGGCTGGGACAGGGGTCCCATCAGACCAACAGGGCTAAAAGCTCAGGCCCTGGCTTGCGAATCGCAAGTCTGCCACTTGCCTGTAGTTACAGAGCAAGGAAGTCTCTTAACCTCTCTGGAACTTTGGTTACCTTCAGTAATGAGGGGAACAAAATTCAATTTCAAAAGCTACTGTGAGGATTTGATGGGAAGTGGGAAGTGCTTAGCAAGAAGTCAGATGAGGCACTTATCTGTTTCAG
Seq C2 exon
CCTGTGGATCCTTGAGGACAGCAGGTCCCCAGGCAGGAGCACCCTCCCCATGGCCCTGGGAGGCCAGGCTGATGCACCAGGGACAGCTGGCCTGTGGCGGAGCCCTGGTGTCAGAGGAGGCGGTGCTAACTGCTGCCCACTGCTTCATTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000151006:ENST00000280606:6
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.149 A=NA C2=0.137
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=PD(20.0=62.2)
A:
NA
C2:
PF0008921=Trypsin=PU(19.5=84.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCGAGCCTGACGGACACT
R:
CCAATGAAGCAGTGGGCAGC
Band lengths:
344-1047
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development