HsaINT0133031 @ hg19
Intron Retention
Gene
ENSG00000151006 | PRSS53
Description
protease, serine, 53 [Source:HGNC Symbol;Acc:34407]
Coordinates
chr16:31095440-31096024:-
Coord C1 exon
chr16:31095879-31096024
Coord A exon
chr16:31095657-31095878
Coord C2 exon
chr16:31095440-31095656
Length
222 bp
Sequences
Splice sites
5' ss Seq
GAGGTGAGC
5' ss Score
8.7
3' ss Seq
TGTCACCTGACCCCTGACAGGGC
3' ss Score
7.42
Exon sequences
Seq C1 exon
GCATCAGCTCCCTCCAGACAGTGCCCGTGACCCTCCTGGGGCCTAGGGCCTGCAGCCGGCTGCATGCAGCTCCTGGGGGTGATGGCAGCCCTATTCTGCCGGGGATGGTGTGTACCAGTGCTGTGGGTGAGCTGCCCAGCTGTGAG
Seq A exon
GTGAGCCCCAGGCCCCCACACCTTACCTAACAGGCCCCTGGCATCCCCTCACCCAATAGCTCAAGAACGGACCTTCCAGGCTTGGCCTCTGGACCCACCTCCCACCTGAAACTAAGCCTTTTTGCCAATTAGCCCCCAAACAGCCAGAGGTTCCCTAGCCTGCTCTACCGTCCTGCACAGCTGCCTATAAAAAGTCACCCAGTGTCACCTGACCCCTGACAG
Seq C2 exon
GGCCTGTCTGGGGCACCACTGGTGCATGAGGTGAGGGGCACATGGTTCCTGGCCGGGCTGCACAGCTTCGGAGATGCTTGCCAAGGCCCCGCCAGGCCGGCGGTCTTCACCGCGCTCCCTGCCTATGAGGACTGGGTCAGCAGTTTGGACTGGCAGGTCTACTTCGCCGAGGAACCAGAGCCCGAGGCTGAGCCTGGAAGCTGCCTGGCCAACATAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000151006-PRSS53:NM_001039503:9
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.068
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=FE(21.8=100)
A:
NA
C2:
PF0008921=Trypsin=PD(20.5=61.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CATCAGCTCCCTCCAGACAGT
R:
CAAACTGCTGACCCAGTCCTC
Band lengths:
292-514
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)