HsaINT0135663 @ hg38
Intron Retention
Gene
ENSG00000126838 | PZP
Description
PZP, alpha-2-macroglobulin like [Source:HGNC Symbol;Acc:HGNC:9750]
Coordinates
chr12:9192193-9192739:-
Coord C1 exon
chr12:9192512-9192739
Coord A exon
chr12:9192257-9192511
Coord C2 exon
chr12:9192193-9192256
Length
255 bp
Sequences
Splice sites
5' ss Seq
CTGGTAAGA
5' ss Score
9.45
3' ss Seq
TCACTGTTTTTTCATTTCAGATC
3' ss Score
12.05
Exon sequences
Seq C1 exon
GTTTTCACTGTGCATCCCAACTTGTGTTTTCACTATTCATGGGTAGCAGAAGACCACCAGGGTGCTCAGCACACTGCAAATCGTGTTTTCTCCTTAAGTGGAAGTTACATTCACCTGGAGCCTGTGGCTGGTACCCTGCCCTGTGGCCACACGGAGACTATCACGGCACACTATACACTGAATAGACAGGCCATGGGAGAGTTATCGGAGCTCAGTTTCCATTACCTG
Seq A exon
GTAAGAATGAGGCCATGGAATACAATTGCAGCTTATCAGTAGGACAAAAGTGGTCAATAGGCTCAGGAATGTCAAAATAAACTACTTGCACACAGCCACCTTGTGTTCTTGTTGTGCGTCCTTCATTCCATGAGTTTTCTTGAGGTTGATTCTCTCCAGCACAGACTTGACAACTGAAAGTGGGTCATGTGGGGAATAGAAGGCTGAGAACTGTGTCCAGCTCAAGAAATTTCCTTCACTGTTTTTTCATTTCAG
Seq C2 exon
ATCATGGCTAAGGGAGTCATCGTCAGATCTGGAACCCACACTCTGCCTGTGGAGTCAGGAGACA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000126838:ENST00000261336:12
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF077039=A2M_N_2=PU(26.2=51.3)
A:
NA
C2:
PF077039=A2M_N_2=FE(14.1=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTTTTCACTGTGCATCCCAACT
R:
TGACTCCACAGGCAGAGTGTG
Band lengths:
285-540
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development