HsaINT0135665 @ hg38
Intron Retention
Gene
ENSG00000126838 | PZP
Description
PZP, alpha-2-macroglobulin like [Source:HGNC Symbol;Acc:HGNC:9750]
Coordinates
chr12:9180983-9182117:-
Coord C1 exon
chr12:9181975-9182117
Coord A exon
chr12:9181133-9181974
Coord C2 exon
chr12:9180983-9181132
Length
842 bp
Sequences
Splice sites
5' ss Seq
AAGGTGAGC
5' ss Score
9.6
3' ss Seq
GTTTCCTTCATTTCCCACAGGTG
3' ss Score
12.68
Exon sequences
Seq C1 exon
TGAAAGGCAGTTTTGCCTTATCCTTCCCTGTGGAGTCAGACGTTGCCCCCATTGCACGAATGTTCATCTTTGCCATTTTACCAGATGGAGAAGTTGTTGGAGACTCTGAAAAATTTGAGATTGAAAACTGTCTAGCCAACAAG
Seq A exon
GTGAGCGATTTAACATAAAATTAAAAGAACACAAATAAATGATACTGTAGGTGCCATCTATTTTACCCCAGAGAAAACTAAGTCCAGAAAAGTAAAATGAGTTGCCCAACAGTTCCCAACAAGTTTATGGCAGACCCAAATTTCTAGGGATCTAGTACAGCACTTTTTCAATTACACAAAGCTGCTACCAAATAAAATACAATCAGTTTTGTGTTCATGATGCTCTTCTCTGCTGATTCAGTTGTGTGAGTATGTAAAATGCTAAGACTCAAAAGTTCCCAAAACCTGAAGAATAAGTGTAAACACCTAGAATTACCTTATCATGTGTCAGAGATAAAGATGGCCATCTAAAAATCTAACAAGGTATCTATCCTTATTCTGCCTCAGTTATCTCCTTAGGACAAGACTAAGCTACCGAGAAGCTATATTTTGTTAAGATTCCCCACTTATGTAATAGTCATGTTTAAAAGAGTGAGTAAATTAATGTGTCGCCAAAGCATTAGATAATTTGGATCCTGTCTAAATAGAATCACTTTTGATCACTGGAGTAGGTAAGCTTGTTATAAAATTAATACTTGCAAACATAAGGGAAGTCATGTACCTTTTAACAGATCTAACTATTTATGTCTCTAGAGTTGTTGGGATCTGTGAAAGTGGTAATAAGTGATTTACAAATTATTTTCTATTTTTAAAGTGAAGGAAAGTTGTAAAAATAGGTTTCTGACTGACATTACCAACATAGTCATATGAACTGAATATAAGGGTGGCTTAGGAAATGCAGGTGACTGCAAGATCACAGAAGTAGGGAAAACACTGGTTGACGTTTCCTTCATTTCCCACAG
Seq C2 exon
GTGGATTTGAGCTTCAGCCCAGCACAAAGTCCCCCAGCCTCACATGCCCACCTGCAAGTAGCAGCTGCTCCGCAGTCCCTCTGTGCCCTTCGTGCTGTGGACCAAAGTGTGCTGCTCATGAAGCCTGAGGCTGAGCTCTCTGTGTCCTCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000126838:ENST00000261336:14
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.020
Domain overlap (PFAM):
C1:
PF077039=A2M_N_2=FE(31.5=100)
A:
NA
C2:
PF077039=A2M_N_2=PD(26.2=78.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCAGTTTTGCCTTATCCTTCCCT
R:
TGAGGACACAGAGAGCTCAGC
Band lengths:
287-1129
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development