HsaINT0135676 @ hg38
Intron Retention
Gene
ENSG00000126838 | PZP
Description
PZP, alpha-2-macroglobulin like [Source:HGNC Symbol;Acc:HGNC:9750]
Coordinates
chr12:9159938-9160490:-
Coord C1 exon
chr12:9160314-9160490
Coord A exon
chr12:9160026-9160313
Coord C2 exon
chr12:9159938-9160025
Length
288 bp
Sequences
Splice sites
5' ss Seq
CTGGTAAGT
5' ss Score
10.65
3' ss Seq
TCTGAAGCCTTCCATTTCAGGTT
3' ss Score
6.7
Exon sequences
Seq C1 exon
GTGACATATTAGGTTCTGCTATGCAAAATATACAAAATCTCCTCCAGATGCCATATGGCTGTGGAGAACAGAACATGGTCCTATTTGCTCCTAACATCTATGTCTTGAACTATCTGAATGAAACCCAGCAGCTGACGCAGGAGATCAAGGCCAAGGCCGTTGGCTATCTCATCACTG
Seq A exon
GTAAGTGAGACAGAGAAAAATTTACTTTGTTACTCTAATGAAACTTTTCCCAATTAAGCTTCAGTTATATCATCAAATATTAACCCATGATGATAATTTTTATGAAAACAACAATCTTCCCACACTCTAATAGGATGTTGTGTTTGATCTATCCATAACATTCACAAAACTATGGCAGATCACAGAAGGTCATAAAATGTCCATGGCGCCTGGATGCATGAGCCTAAACATATGGATGGCCTGCCTTTCTTTAATGCTTCATGAACAATCTGAAGCCTTCCATTTCAG
Seq C2 exon
GTTACCAGAGACAGCTGAACTACAAACACCAAGATGGCTCCTACAGCACCTTTGGGGAACGATATGGCAGGAACCAGGGCAACACTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000126838:ENST00000261336:24
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.033
Domain overlap (PFAM):
C1:
PF105694=Thiol-ester_cl=WD(100=51.7),PF076789=A2M_comp=PU(0.4=1.7)
A:
NA
C2:
PF076789=A2M_comp=FE(11.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGACATATTAGGTTCTGCTATGCA
R:
CAAGTGTTGCCCTGGTTCCTG
Band lengths:
265-553
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development