HsaINT0137405 @ hg38
Intron Retention
Gene
ENSG00000091428 | RAPGEF4
Description
Rap guanine nucleotide exchange factor 4 [Source:HGNC Symbol;Acc:HGNC:16626]
Coordinates
chr2:173033914-173036212:+
Coord C1 exon
chr2:173033914-173033964
Coord A exon
chr2:173033965-173036124
Coord C2 exon
chr2:173036125-173036212
Length
2160 bp
Sequences
Splice sites
5' ss Seq
ATGGTAAGT
5' ss Score
11.01
3' ss Seq
ATCTCTTTTTCTCTCCTAAGGAC
3' ss Score
9.93
Exon sequences
Seq C1 exon
AAACTGCCAAGCAAGTTCAAGAAGTTCTATGCGGAGTTTGAAAGTTTAATG
Seq A exon
GTAAGTGACAGTGGCTTCTTTATTCTGTTCACTGTCTACATTAATCCAATTTCTGATTAGCTGAATTGAAGTTCTCATTTTGGAAATTTTATCTGTCCTTATATGACTTTAAGAAGTTTATGATCCCTTTTAGTGCTGCTAAAACAAGCATGTCTGACTAATGAATGGCACCCTCAGGAACTAACTTAAAGAGGACTTATGTCCCACATAAGGTCAATTTGTATAACTAAGAAAAGCAGTGTAATAGCGTCCTCTCCATCCAGCTCAGGTTGGCTATGGGTTGGAAGCTGCATTTTCCTTGGCTTGCCAAGATTATTTTTCCCCGTTGGCTGGAGGTGTTAGACAGAAAAGGAGTGAGTTGGGCTCGCCGGGAGTGATGGGCAGGTTTCAGAGGGCAAATCGGGACAGGGATCGGCTGTGCAGGGCAGAGAGTGAGTGAGCCAGACACCCAGGAAGAAGACGGGGCTTCAGGAAAAGGGGAATCTTGCAGTAGAGGTTTCATTTTTGCTTTCATAGGAAATATCTCCCCTTGGCCCCTGTATGCAAATCTCTTTTTCAAACAAGAAGGGGAAAAGAAAACTCCAAATTTTTTATGCCATAAGTGAAGTTATTTTAAAACACAAATCAGGCCAGGCGCAGTGGTTCATACCTGTAATCCCAGCACTTTGGGAGGCCAGGAAAGGTGGATTACTTGAGGTCAGGAATTCGAGACCAGCCTGGCCAACATGACGAAACCCCATCTCTACAAAAAATACAAAAATTAGCCAGATGTGGTGGCCTACACCTGTGGTCCCAGCTACTCAGGAGGCGGAGATGGGAAGATCGCTTGAGCCAGGAGGTGGCGGCTACAGTGAGTAGTGACTGGGCCACTGCACTCCAGCCTGGGTGACAGAGTGCGACCCCGTCTCAACACACACACACACACACACACACACACACACACACAAATACAAATCAATTTGTTTAACTAAGTCTACCTTTCTTTTGTAGCTATATTTGATTCAGAAATACAGTTGAGCCTTGAATAACTCAGGGGTTGGGGCACTAACACCTCCACCCCCATGCAGTAGAAATATTGAGTATAACTTTTTATTATTATTATTATTTTGAGTCTGGGTCTCACTCTGTCACCAAGGCTGGAGTGCAGTGGTGCAATCATGACTCATTGCAGCCTTGACCTCTTGGGCTCAAGCAATCCCCCGACCTCAGCCTTCCAAATAGCCTCCCAAATAATTTTTTATTTTTTAAAAAACAGGGGTCTCGGCCAGGCACGGTGGCTCACACCTATAATCCCAGCACTTTGGGAGGCCGAGGCGGGCAGATCACGAGGTCAGGAGATCAAGACCATTCTGGCTAACATGGTGAAACCCCGTCTCTACTAAAAAAATACAAAAAAATTAGCCAGGCCTGGTGGCAAGCACCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACTCGGGAGGCAGAGCTTGCAGTGAGCGGAGATCGCGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACTCTGTCTCCAAAAAAAAAAAAAAAAAGGGATCTCACTTGGGGTCTCACTATTTTACCCAAGCTGGTCATGAACTCCTAGGCTCAAGCGATACTCCTGCCTTGGCCTCCAAAAGTGCTGGGATTATAGGCATGAGCCAATCATGCCCAGCCCAAGCATAACTTTTGACTTTCCCCAAATTTAACCACTAATAGCCTACTGTTGACTAGAGGCCTTACTGATAACATAAAGTCAACTAACACATATTTTGTATGTTATATGTATTATTATGTACTATATTCTTACAATAATGTAAGTTAGAGAAAAAATGATAAGACAATTATAAGGAAGAGAAAATGTACTGACTGTTCATTAAAGGGAAGTGTATCATCATAAAGGTCTTCATCCTTGTCCTCTTCTTGTTGAGTAGGCTCAGGAGGAGGAGAAGGGGTTGTTGGTCTTACAGTGTCAGGGATGGCAGAGGCAGAAGAAAAGCCATGTATAAGTGACCCACACAATTCAAACCTGTGTTGTTCAAAGGTCAACTGTACCTGATTGTGGGGTGAAAGGCAGGTGTATTAGGAGGTAACAAAGGGTGGTGTATCTGTCACCAGTCATTACCATCATCTCTTTTTCTCTCCTAAG
Seq C2 exon
GACCCTTCAAGGAACCACAGGGCCTACAGGCTGACAGTAGCTAAGCTGGAACCTCCTCTCATCCCCTTCATGCCTTTGCTCATTAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000091428:ENST00000397081:27
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0061714=RasGEF=FE(8.6=100)
A:
NA
C2:
PF0061714=RasGEF=FE(15.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development