HsaINT0137433 @ hg19
Intron Retention
Gene
ENSG00000136237 | RAPGEF5
Description
Rap guanine nucleotide exchange factor (GEF) 5 [Source:HGNC Symbol;Acc:16862]
Coordinates
chr7:22157908-22165276:-
Coord C1 exon
chr7:22165222-22165276
Coord A exon
chr7:22162140-22165221
Coord C2 exon
chr7:22157908-22162139
Length
3082 bp
Sequences
Splice sites
5' ss Seq
TTGGTGAGT
5' ss Score
9.27
3' ss Seq
TTTCCCCCTCTAAACAACAGGTG
3' ss Score
7.92
Exon sequences
Seq C1 exon
CATATGATCGCAGACACTGTCCGAACCCTGAGACACTGCAGGACTAACCAGTTTG
Seq A exon
GTGAGTAATTGAAGTCAGGTGCGGAATGTAAATTGACTCTACGTTGGTACCAACTGTGGTCACAAGTATTGGGTGGTAATCAATTTAAACAGATTGAAAAGTATCATATGTATATACATACGCATATTGTATATATATAGTAGATTGTCTCTTTGTTTCCTCACTGCATGTTGGGGATGCAGAGGAAGACAAGATATGGCAGATTATTATCCCCTCATGGCAGCAAGTTTATGCTGTGAAGAGTGACTTTACACACTCAGAAACCTCCTCCCCGCAACTCCCGCTGACTCCTGTCCCCACAGTGTCTTGCTTTGCTTGTCCATTGGCTCAAAATCACTGGTGAGTTTAGCAGGGGTGACCTTGCCCCTAACCTCTTTGCGTGGAGCCTTCCTGGAATAGGACTATAGCTTGTAAAAGTGCCTAAAGCAGCCTTCCAGAATCTTTTCTCCTCTCCAACAAAAACTTCCTGTCTGGAGCTGCCTTTCAGCTGCAAAAGTGTGGTTCTGAGCACTTTTGTAGAATCCCCACTGAGACTAATGTATGTAGGAATATTTGTTCCTTTTTAAATCTCAGCCATAATTTATACTATGTTTAAATGGTGTTAGAACATTGCAGGAAGGAAGGAAATCAACTTCATTGAGTTGAAGGAGCTTTCACATGGGCAATGGAATCCTGACATCAGTCCTAGCAAATGGGGATTATTAACCCTGTAGGTGTAGAACAAAAAGCAGAGACTCAGAGAGATTCACTTATTTAGCTATTATTCAGACTGAGTCTACCTTACCTCCTCGCCCTCTCTTTTGCCCTCTACAGATCCTGTGGATACAAAGGGTAATAAAAAATAGAAAATTGAGTTCAATAATTATAAATTAATCAAAGGCAACCACTCAGTTCAACTTCATTTTTTAAGTAAGACATGCCCATTGTAAAACAATTTTTTCAACAATATAGAAGTCTATATAAAGTAGAAAATCAGAGTCCTACTTCTCAAGAAAAGTACTGCTAACAATTGAGTACACCTGCTTAAGAATTTTTTTCTGTTCAGTGCTGGTCTAGGCTGGCAATATTGTCCCCCAACAAAGTAAGTTAGGAACTGGACTTCTGTGTGGATTATGTTTTCTCTTTGAAAAGGAGACTTATAAATACAGGACCTAATTTTCTAAATATTCACATCAATTAGTACCACTTTAATATACCTATATAATTCTTCATCAAGCATACAAGCGCAATGCAGTTACAATAAAAATAGTAATCATAACATCATCACAGAGATTCACTGAAATGTATAAGCATAATGCTGATGAGTACAGCTTCATATTGCTTTTATCCTCCTTTGCTTCCCAAGTGTTTACTGGGGATTCAGCTAATTCTAAGATATCAGTCTCACTTAACCAAGGAACTCTAGTTTATATATGCTCCAAGTATAGACAGGAAGGTGATAGTTATACTAACTTGTGTGGCCTTGAACCTGCCTTGAACCTCCCACTCATCAGAGAGCAACCCTCTGTGTGGCACTGAGCAAAGGAGAAATTTAAGTAACTATCAAGCCAGTTGATGTTCTAATATTTATATACAGTATCTTTAAAAAATTGGTTTGGGAACTGAATTATCCGAATTCATTTTAACGGTTTATATGAGCATAGTAAACCAATGTCAGCATTTGGGATAAAATATGAAAATGTTAATCAAGTCACTTATGCATTATAAAGTGTCATGCAAATGTCAGTTGCCATGGTTAGAACCATTCATTGTGCCATCTTTTTAAGGCTTGAAAATTAACATAAAATTACCTTTGTAGCATCGTGTTATCCAAACCAATGTTTAACTTTCTCGACGTCTTCCAGAGAAGGCATTCTGGAATAAAACAGCTTTTTGTTACTTTCAAACAGGTGGGATGGTATAAACTTTAACACCTAGTGTGTTTACTTGCTAAAACCAGGAAGCCTTGTTTCTATTAAACCTAAGAATTATAAGCCACCCATGTCATACAGGTCTTAAATTATTTCCTCATAAAATACATTTGTTATAGAGGAGAAAAAAGGGGGTTTCACCAAGAGAAAAAAATGCTATAAGAAAATGCTCAGCCTCCTGCATTTCCCTTCCCTCTGCTCAAACTGAGCTCCAGCAGCTCACCCTGCCTGTCCCATGCATAATCTACAAAGCAACAGGATATGATGTCTTCACCACTCACCTTTCCATTGTTTTACTGTAGTGCAGTTTGGCCAGTGTTCCCCAGCCTCAAATGGTTTGCTTGTGTGTGTGTGTGTTTGACTGTGGTGCACGGGCTTGCCTCGTGGTTCATGCTGCTTCATCCTGGTTCCTTATCAGCACGGACGCTAGCAGGGTGTGGATGTGTTCACAGTGCACTAAAGCCTCCTTTGGCCCCTCGATTCCTTGACTGCCCTAGATATGTGAGTGGAAAAGCCCCTTGTCTTGTCCTTCTCTGGGTAGACTTTAGTCCATACACATACTTTCTGAAGCTATTTCGTCTGTTAACCACATCTTAGAGTCTGTTCTGTTGTATCTGTTCATTCAGTTGCTCCATTAAATTTTTTTTTCCAAAAAATGAGAATACCAAAGAATTGTACAAAATCTAAACAACAGAAAAAGAGTGATTGCATTCATATGCTAAATACATTATCAGCGATTTTCAACGCTTCTAGACTGAGATATAGGACCCAGTGCTGGCCATTTAAACAGGTAACTGCTGTGAAAGGCTACCTAAAAGGGCTCAGGAACCATCTGTCCTGGGTCCGAATCCTGGCTGTGACAGTTAACTTGCTGCGTGACTGTGCTCAGTTTCCCCATCTGTGGAATGAGATAATAACGTAATTTCTAAATAATATACAATGTTAGGTAATAAATGCTATAAGTATCCTGCCAGTCTGATTGCCTGACCTGAGGAATCCATTCTGAGCTGAAAAAGCATTTCTACTGTAGGACAAGGACACCTCTTATGGGATTCTGACTAATGAGAACCCACCTAGTACATTTACTCAGCCTTAGTGTGGGGTTTTGTTGGTATGTAGATACAGCATTACTGCTCTCCTGAGATTGTCTTTTTTCCCCCTCTAAACAACAG
Seq C2 exon
GTGACCTGTCTCCAAAAGAGCATCAAGAGTTAAAGTCCTATGTTAATCACCTGTATGTCATTGACAGCCAGCAGGCTCTGTTTGAGCTCTCACACAGGATCGAGCCTCGGGTGTGAGCCCCACTGCCTCACCTCCCCTGTATCTGCAGCACTTTGAGCTACGGGAATGTCTATGCCAAGCACGTTGCTTTCCTGTGAGAAAAGAAGTTGCTGAGTTTTATCAGTATAACCCAAGACATTCACAGGAAAGCCAGCCAAAGCGTGTTCAGGAAGTGATGTCAGCCACCAGAGAGGGGGAGAGGTTTCTCCATGCTACTCTCGGGACAAGAAGGCAGAAGGAGAGTCAGAAGCATTCTTGAGATGGAGAAGGCTGGTTTCTTATGATCACATTGTTGATCCAGTCCAGTTTTCAATATGAGATGTGCCAGCATCAAGACAAGACAACGTCTTGACATGCAATGACCAAATATTTCATTAAGAGCGTGCATGAAACAGGAAGGAGTTTTTACTTTGCCTAGTTTTAGATTACTGTCCATAAGCTGTCAAAGAAGTCATTCTTTTGAACACCTGATGACAGAGACAGCATCTCTAGATCTCCAGGGAGGAGAGGTTTCTGTTGATACAACCTGTGACATCACCAAAAGCCACTTGTGTCTAGGGAGTTAGTGAGGACTGCAGCTAGCATCCATGCTCTGATGGGCAGATGAACAATGTCAAGGTGTGCATCACTTTGCACCACAATCAACTATTGACACATGCTTGCAGGTGAAATTAGTTTCTGTACAACTGATTTGCAGCTATAGGCAAGGTAGATGAAGTTGCTTTGCCAGTAAGGAAAAATAGTAATCTTTAAGAAATTGACTCATTGTTTAATTTCTGGGGATTTTCTTTATACTTCTAAGCAGGCTCTTATCTTTTATTGGACATAATATGATTTTGAAAAAGCACAGTGCCTGACACATTGCAAACACTCACCAACTGCTTGCTGAGGTGACAGAGTCACAAAAGTCTGCATTCTTGTGCCTGATGATGCATTTTGCGTACCTCATACAGGCTCCTTGCCCACACTATGGAATGACAGCAGCCAGTGCAGGGAGGTTAAGTGACATTTAATGAGTGAAGCACTTAGCACTCTCTAGGTAATAAGATAGTGGTAATTACTAGTGTTTTGGCAAATGAAAAATGCCCTGAAATAGCCAAATGTCTGATTAATGTTGGCAACTTAGAAGTCCTATAATCCAACTACCAGCCAAAGCAGGGAGCCTTTCTATAATTTGCCTTTTTTTTTTTTTTTTTCAAAATCTGAGTCTTCTAAAATCTTATTATTCCCATTTTTACCAATTGAGGCTCCTGTAGCAAATAAGACCTCTTGATATTTTCAAGGACTGGTTAGAGGATTTCTTTCAACCTTCACATGAACAAAACAGCCTATGGGTCAAAATAATGAAATCCACCCCTGCCTGCTAGATACTTGTCACCTTGCTAAAATGCAAGGGCCTGGTCCATTCATTTTCCAAATGCAGGAGTCTTGGTGCACTTCTCACTCTTCCTGCCTGTTCATCTCTTTCATGCCCACACAGACCTGTTTCCTTTTTGTCTCATCAACGCCTCATTCATCCTCATTACTGAGGCGTGTCCAATGCTTTTTGACATCTTTATAGCAGTGCTGTTTCCTGGGCTCAGGAACCACACTGAGCTTGAGATACTGCTGGAAGGAACCATGTGGAGAGAAGGTTTGGGAGAACTTTGAGAGAGACTTAGTTTGGCCCAGCATGTAAAACTTCAGTCCTGAACATTTATAGGGTTTTATAGAAGGGCATCCTCCAGGGCTGGTCCATTCAGAGAAATGCTGCATGCTGCCGTCATGGAATGTGGCCCACAGGACACCAGAGCCGTGAGAACCGGAGAGCAGACTTCCCTCACGGCTGGGCTGAGCAAACCCTCCAAAGCCCTCCTCACGCAGTTACTAACAATAGCATGGGCTTACAGCACAAGCACGTGTTCTCACCTTTTTCCTATGCCCTGGACTAAGGTTTGGCCAGTGTAATCATATAAGGCCATCCTGACATTGTTTCTGTGTTTCAAAATTTGGATTTTTATTTACATTAGAACTACATTGCTCCTAGTAGAACATTACCTTTAGGGGACTAATTTTCCATGGAGAACTATTTCAGCATATTGCATGCTGCTCAGACCCCAAGTCAGATATGCCCACCAAGCCAGATGAAGCTACACAAATGTGGTATTTAAATGCATTTTGTACAGTGACTTCAGAGTATCTCACATGACATGGGTGTAAACTGGCTGGGGAGAAAATGATGCTTGTTCACCTCTTCCTCCAGCCGTGGTTAGGTGGTCCTAGGGGTAGCAGAGGGAAGGGAGGATTTTGTGCAGTCAAGATTTGCTTTTCCATCCTTGTCTTCTGAATGTCTAAAATCTCTGCATCTTTCTGAAGTTTAACAACTGTCTCCAGAGGTTTGCCAGGCAGCAGCTCTCAGAAGTTTCCAAAGCTTTGCAGAATCTTAGATCTGGAATTAAAGAATTCAAGCCCGAATTGTGAGAACCAGATATTACTCAACAGAAAGCTCTTTCTAAGGAATCTGAGCTGTTCACTGGTGGACAGTGGTGGGGCTTGAGTGCTCCTTGTTAATAGGATGGGCCATGCACCCTCTCTGGATATTCACCAAGGCCTCTTCAGAATAGGGTTTGTTCTGGCTAGAAGCGTGGTCTAGAAGATGGCTAAGCTCTTTGCCAGCTCTCATTTGGAGTTTTATTATTGCATAAAATCTTCGCTCACTCTGCAAATCTTACGTAATCTGGCACCTTCGGCACCAGGTGGTGCAGGGGCACTTCTAAGTGGGCTCTTTTTGTTACAGCACAACTCTCAGACAGTCCTGTGGGTCTTTGGATTCGTCAGCATTCCAGCAAACTAGCCCTGCTTAGAAGTTAGCACAAGACAGCAGAATGCAGGACCCCGTAGGCAAAATCACAACCTTGCTATTAAAAAAAATTTTGTTTTACATACACATTTGCAGGTGTTCCCTAGAGTGTGGTGTTTTGAATTTGCTCTTTGTCATCTGTATAATTGCCAAATGATTATAGTGATACACATGACCTGCATTCACTTTTTTCTAGTTTCCTTAATTATGTTTAGAATAAATTCATTTCCCTAGACCGAGAACCACAAACAGGTAGTGTGGAGCATACACCGAATTTAGAAGCATGTGGATAAGGTCAGTGCTCACACTGCCTAGTCCACAGGGAGAGGATGCTGCATGAATATATACTTGCCTCTGAGTGGAGGAGAAATCGTGGCATGAAAGAGAGAGTACCAGTGATGACTTCTTATCCCTGGAGCTGGGCTTTCACTGCTACCCATATCCCAGCCCTGCGAGTCTGTTCTAGCCAGCACAGACACCGCAGATCCGGAACTGAATGTTCCTAAATGGCGCAGCCAATCCAGGCTTTTCAGAAACTGGGCAAAAACATTAAAATGGGGACGATCGGGTCTTCCGCAGTGGTCCAACACAGGATTTCTTTTAAATGTTTCAAAAACATGTCCTTAAAATTTCAGCCTGCTTCTTAGCGAGTGGGCCAGTTTTGCTTAAAACTGGTGGGGGGGCGGGGGGGAAGTTTTTAAAAATTGCCAAAAAGTTAGATGCAAATGTATTACTGTATAAAGCAAAGCTGTATATACTAAACATTTTTTAGCAGAGTAATATTTATTTGCATAGTCTATTTATTGTATTCGTATCACACTGTTATTAAATACTGGGATGAAATCAGTGACCTGAAGCAAGAAATCTTGCCTTTTAATGTATCATTAATTAGGGCTGCTGTGATATTGTCAGCTTGCATTAACAATTAGAAGATAGAGAACCCGCCATCAGGGTGTCTACCTAACTTCTCAGGGACTACACTTGGTAGTTTTCCACCATTTAAAGAACTGGTAAATATGAAACATTTGTTGAGTTACCAGAATTGCCATTAACAGTGTTTTCTTTCCCATATTCCATGCTTTCTGCCTCTGTGTATATATATAATATATATGTATATGACTGTGCTGTGTATTTATCGAAGCTAGTAAGCAATAATTTATATGTAAAAATGGCCAAGCAATATAAGGTTAAAACTTATATAAGTAACCCTTACCTTATCTTGTATTTTCAATTTTTTTTTAAAACTGCTTTTCCAAATATGAGACTATGTTAAAGACACTATTCATGCCTCTTA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136237-RAPGEF5:NM_012294:25
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.053 A=NA C2=0.026
Domain overlap (PFAM):
C1:
PF0061714=RasGEF=PD(0.5=5.3)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)