HsaINT0137722 @ hg38
Intron Retention
Gene
ENSG00000105122 | RASAL3
Description
RAS protein activator like 3 [Source:HGNC Symbol;Acc:HGNC:26129]
Coordinates
chr19:15452658-15453497:-
Coord C1 exon
chr19:15453107-15453497
Coord A exon
chr19:15452816-15453106
Coord C2 exon
chr19:15452658-15452815
Length
291 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAGG
5' ss Score
10.51
3' ss Seq
CAGCTGCTCTCCCACCACAGTTG
3' ss Score
6.7
Exon sequences
Seq C1 exon
CCTCTCCGCAGGGGAGAAGCCCGGCTTCCTGGCCCCCCGGGACCTCCCCAAGCACACCCCTCTCATCTCCAAGAGCCAGTCTCTGCGCAGCGTTCGCCGCTCAGAGAGTTGGGCCCGGCCACGGCCGGACGAAGAGCGGCCCCTGCGGCGGCCCCGGCCGGTGCAGCGCACGCAGAGTGTCCCGGTCCGGCGTCCTGCCCGCCGCCGCCAATCTGCGGGGCCCTGGCCGCGACCCAAAGGCTCCCTGAGCATGGGACCAGCGCCCCGCGCCCGGCCTTGGACCCGGGACTCCGCCTCGCTGCCTCGGAAGCCGTCGGTACCCTGGCAGCGCCAAATGGACCAGCCGCAAGACCGAAACCAGGCACTGGGCACGCACCGACCTGTGAACAAG
Seq A exon
GTAAGGTCAGGCCCAGGTCCGCGCCTGGGGAGTGGGAACAGGGACGCGACTGGGGAAGACTGAAGGGCCAGGCAAGTCTGGGTTCAAGTACCCAGCTCGCTGTGCTGTGTGACCCCAGGCCTAGCCCGACCCTCTCTGAGCTTCAGTCTCCCCAGCTGTACCGCAGGAGGGATGTTCCCCAACTAGGCAGGCCGGTGATGACGCTGAGCGCTTGGGCCTGGGAGGTCAGGGTCTCCGGGGAGACACAGGGGCGGGACAACGGGTCAGATTACAGCTGCTCTCCCACCACAG
Seq C2 exon
TTGGCAGAGCTGCAGTGCGAGGTGGCCGCTCTGCGTGAGGAGCAGAAAGTGCTGTCCCGCCTCGTGGAGTCGCTGAGCACCCAAATCCGGGCCTTGACGGAGCAGCAGGAGCAGCTGCGGGGCCAGCTGCAGGATCTGGACTCCAGGCTCCGTGCTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000105122:ENST00000343625:15
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=NA C2=0.623
Domain overlap (PFAM):
C1:
PF041569=IncA=PU(22.9=22.9),PF154501=DUF4631=PU(11.5=9.9),PF045827=Reo_sigmaC=PU(11.3=9.9),PF123293=TMF_DNA_bd=PU(2.9=1.5)
A:
NA
C2:
PF041569=IncA=FE(39.7=100),PF154501=DUF4631=FE(46.0=100),PF045827=Reo_sigmaC=FE(45.2=100),PF123293=TMF_DNA_bd=FE(74.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCCCTGAGCATGGGACCAG
R:
GGAGTCCAGATCCTGCAGCT
Band lengths:
295-586
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development