HsaINT0146134 @ hg38
Intron Retention
Gene
ENSG00000136193 | SCRN1
Description
secernin 1 [Source:HGNC Symbol;Acc:HGNC:22192]
Coordinates
chr7:29940682-29944179:-
Coord C1 exon
chr7:29943977-29944179
Coord A exon
chr7:29940877-29943976
Coord C2 exon
chr7:29940682-29940876
Length
3100 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGT
5' ss Score
10.67
3' ss Seq
GGGCTTTGCACTCTCTGCAGAGG
3' ss Score
7.01
Exon sequences
Seq C1 exon
GCTTGGTTTAGAAAGAGGGGAAACAGCTAAAGAAGCCTTAGATGTCATTGTCTCCTTGTTGGAAGAACATGGACAAGGTGGGAATTACTTTGAAGATGCAAACTCCTGCCACAGCTTCCAAAGTGCATATCTGATTGTGGATCGTGATGAAGCCTGGGTGCTCGAGACCATAGGGAAGTACTGGGCTGCCGAGAAAGTCACAG
Seq A exon
GTGAGTGGGTGTGGATGATGGAGAGTTCTGAGGACAGGGAAGGCCACAGAGATGGGGTGGCCTGCACGTACAGTGTCAGACCTGGAAGAAAGACGTGCCGTTGCAGGTCCTCTCTGTGTGGGACTGTCATGCTTTGGCATGCCTCTCATTTCTGGGAACCTCCAAGAAGAGAACCTGGAGTCTCCTGAACCTGGAGTGAAGCAGTCTCTTAACATTTCGTATTTTCTGTTTGCTTTCTGGGAAGAACCTGCTTTTGACTACCAGGAATTCCATGACTTAAACCATTACTCTATTAATTGGCCAAGAGAATGGTGACTCTTCTTGTGTAATAGGTCAACAAGTCCCTTCACTGGACAGTAGCTCCTTGTCACCCCCAACCCTGTAGATCTTTGTGCTTGGCATGTTCCTCTAAAATAGGAGTTTAGATCTGTGTGAGGACCGGTATACGCCACTCTGGGATTTCTTTGTGAGTGAAGTTCATTTATCTCACAGTGAGACAGTGTTTCTAGAAGAGCAGAGGACTAGATGATCCACCCAGAAGAATTTAGTGCCCATAAATTTGCTGCTCTGTGGCCCGTGCAGCATCTTGCTTCTAACACAGCCCTGGGGAAGTAAGTGTTAGGGGTGGGAGTGGTAGTTTTGTATCCCCACCTCAGCATCCTCATTTCTGGACAGGATGAGATCCCAGAATGGGTTAAAGGGCTTCGAAGAGAACTAAGTAGTCCTAAGAGGGAATTTTGGCCCGAGCAGCTCCTTGGGACTGGGTGGTGACCATGTGATGTGTGCACTGCCATTCTTCCCTCCTGTGCTAATGGTGGAGTAGTAGGTCACGACACTTCTCTTTCGTTGAACCTATTCTTGGCCTATGTATTTTTCTTAACTAAATTTACCAGGAAGTCTCTTCCAAGTAATCCAAAATGATGTTGGGGATGAAACTTGTGTGCCGTCCCTATCTTAGGGGTGAATTGAACCAAATTTGACCCGAGTTAGAAGCGGAAGATCTACCACAGTAGATGGGAATCAAGCCTGTTTTCTGTGCACAAAGTTAGTCCAGTGATCAGGGCTTCTCTGGATGATGGGTACGTTGTACTCTATACAAAATTGCCCCAGTGAGGCAGTGAAATCTAGACTGTGGCTTCCTGGCCAAGCTGTATGAAGGCTGTGTCTGTCTGGAGGAGGGGGTGGCCTCTTTCTATCTCAAAAGGGTGTAGAATGGGCTAGTGGTGTCCGTCAGCAATCACGGAGAGTTTCTCCACCTCATATGCCCAGCATGTACCCACCTACCAGTGTGTGTGCCTACTTGCCCAGCTCTTACAGTAGTTCTAGAACTAAGACAGCCAGTGCAGCCCACCAGGTCTCCAACTCTCCTACAATGCAGGAACTTAAAACTCCTTGATAAAAACCCCTCCTAAGATGAAGTCTTACTATTGAATGCTTCCATCAAGAGTGCTAGTAATCCATGCTTCAAAGCAGTCATATTGCTTTTAAGTTGAACCTAACACTTTTTGATCTATGACTGCGTTTCAAAAGCTGAGCGTCTCTTCAAAATGTAGCTTAAAAAATTACACAAAATGAATGCTTCCATTAGTTAACTAAATATTTAAATAAAAAAGAACCCCAGCCATTTCTTGGACTTACTGATTTCATGTCGTCTGATCCCAGCAGCGGTGTGATGGATTGCAGTAAGATTTAATGCACTCCGTCTCCCAAAGGCTAACATTCTTAAAAGCAAATGTCTACTATAAATCTGCCCACTGGGAAACTAATATCTGTAGAGTTGCTTACAAGAGTATTTTTTAAAATAACTTAGTAGGAATGATGTCAAAATCACTTGTTTAGGCCAAAACTGGTTTTTATTTTTAATTGTTTATAATTGTACTTTTATGGTCCTCTCTGAAAAGATAAATGACAAAGGACCAATGCCTACCAGCCAGGAATGCTTATTTCAGAAGTGTAAATCAGTGAAGCAAAACATACTGAAAGAACTTAGTCCAGCACTGATCCTGCCTCTAGGAACTGGTTTTCAGGCAATGATGGCTTTCCTGTAGCTTGTAGTTTATGTTCTTTATGTCACTTCATTCTCCAAGAATCCCTGGAAGCAGCAAATAGGAATGGCCCTTTTAAGCTAGCACTGATAACTTCCTAGTGTTTGTGCCCTAGACAGCATCTTGAAGCTGGAAGGCTGAGTTGTCCTGTGTGCATTTGCAGCTCAGGCTTCGAAGAAGACATAGCAAGCCAGCCAGCTGGTAGGAGAGTTTCTGGTCTAAGCCCTCATTCATCAAAGTGAAATGTACTCAGAATGCAGGCATTTCTAATTCTAGATTTATTTAGTCACACTTCTATTTTTATAAGAAAAAATTTCCCATAGATTTTTCAAACACATACACACACGCATGCACACACTTTATCTCACACACTCACACGCATGTGTGCACACACACATACCCAGACATATGTATATTCATGAATATATTCAATTATTTTAAAACAATTTGTTGTCATTGCCACTATGATTTTCTAAATGTTGAGACCTGAAAAAAAAGTTGAATGAAGTATTTGATTTGTATTTTTTAAAAAAAACCATATAGATTTGGCCAAGGAGTAGGGGTGTAAAGTGTTTTTCCAGGTGAAAAGAAATCAGACCAGGGAGGGGGCTTTCTATAGATGCGATAGAGCATTGCTGTAGAGGAACAGCATCTCTATTATAGAGGACTCCCTTGTGGATTGCTAAGTCTTGTTAGCTCAGTACCTCTTTCAAAGGACCTGTCCCTTTTTTTGCATGTAACTAATGAATGCTTGGGGCTTATTTAGCCAAAATGAAGAGCCTTACATATTTCCTGTTGATTATGCTTTTAAGATGGGTTAAGTGACTGTTGCTCATTTAAAATGTGATAATGCCCAGTCAAGACTGGTCAGACCTTTTAGGAGGTCTCCTAGAAAGAGACTCAATGATTGTCTGTTTCTCTCTTCAAAAATTAAATGGATTCCTCCCTGTAGTTAAAGTCAGTGTTTCAGGAAAAGGATTCCCTATACATTTCCATTTGTTGATTAAGTCTTTATAAGTATATTTTTAACTTATGGGGCTTTGCACTCTCTGCAG
Seq C2 exon
AGGGAGTGAGGTGCATTTGCAGTCAGCTTTCGCTCACCACTAAGATGGATGCAGAGCATCCGGAACTCAGGAGTTACGCTCAGAGCCAAGGTTGGTGGACGGGAGAGGGCGAGTTCAATTTTTCCGAAGTCTTTTCTCCAGTTGAGGATCATCTAGACTGCGGTGCTGGCAAAGACAGCTTAGAAAAACAAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136193:ENST00000242059:4
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.085
Domain overlap (PFAM):
C1:
PF0357710=Peptidase_C69=FE(31.3=100)
A:
NA
C2:
PF0357710=Peptidase_C69=PD(24.4=80.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development