HsaINT0146207 @ hg38
Intron Retention
Gene
ENSG00000175356 | SCUBE2
Description
signal peptide, CUB domain and EGF like domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30425]
Coordinates
chr11:9021876-9025854:-
Coord C1 exon
chr11:9025702-9025854
Coord A exon
chr11:9021956-9025701
Coord C2 exon
chr11:9021876-9021955
Length
3746 bp
Sequences
Splice sites
5' ss Seq
ATGGTAAGC
5' ss Score
9.26
3' ss Seq
CATGTTCTTTATTCCAACAGAGG
3' ss Score
8.43
Exon sequences
Seq C1 exon
CTTCATCCAATTCTGTGACAACATATGAAACCTGCCAGACCTACGAACGCCCCATCGCCTTCACCTCCAGGTCAAAGAAGCTGTGGATTCAGTTCAAGTCCAATGAAGGGAACAGCGCTAGAGGGTTCCAGGTCCCATACGTGACATATGATG
Seq A exon
GTAAGCACAGCCTGCAGCACATGGAAAGAGCGTCTCTGCTTTGAACAGAGCCAACTTCGGAGCCAGCTGGCAAACTGCTGACAAGCACACATGCTCAGAAAGGCAGGCAAGATGAGGGGAAAAGACATTGCTGACTCACAAGTGCCAAATTTTAACAGGCATTTGGGGACACTGACAATAGGAGGAAAAGATGTTTTATAAAATATATTAAAAGTGAGCATAGCTTGGTGAGTAAGAACATGGGCACTGGAGTCAGACTGATTAGCCTGGCTATGATTTCTCTGTGACTGTGTATGCCACCATCTCTAAGCCTCAAGTTCTTAATGTGCGAATGAGGATAATCATTAGACTTATTTAAGAGTTCAGTGAGAGTTCCTAAAGGACGTGAGGCAGTGCCTGGCACATAGCAATTGTTCAGTAAATATTAACTTCTGATGATTGTGGCTTTTATTAGGTAGAATCCTGAGGCAGGGAAGGACCTTAGTTCTGGTCCTGGCTTTTTCACTGACTCACTGTGGGATCTTGGGCAAGTCAGATGACTTCTGTTTTAATTTTCTTCATGTTAGATGAAGAGGTGGCCCATCTGAGCCCTGGGGCTCTACCTAGCTCTGAGACTTGGTTGGAAAACATTGACTAGGAGCATAAAATGAACTGGATCTTTGTCCTGGAGGACTACACAGTCCTGTAGGAGAGGAGTCATTTGTTTCTTCCTGAGCTTATTTGTTCACCTAGCCAACAAATATTTAATGAGCATCTACTATGTCAGGCATTGGCCTAAGTGCTGGAAACAACATGGTTAGTGACAGAAACACAAAATATATATATTGTTATAGCTGCTATAACAGCCCAAAGCCCTATGTGAGCATGGAAGCAGCAGCAGCAGTTAATTTTACATGAGCTTTTAGAAGGAATAGAGCAAAGTCTTGAGAGATGTGGGTCTTGAAATAACATATACATTTTGAGCATAAATGGGGGAGAAGGACATTCAGAAAGAGGGAAGGACATAAGTCAAAGGATGAAGTACCCCGGTGTACGTGTGGACTGACGAATGGTCTTATTTGGTCAGTGGGTTGGGTGTGTGGGGCTTGGCAGTGAGAGAGGAGACTAGAAGGGAATGGGGTTCAGCTGTGAAGAGCCTTCAGGGCCAAGCTCTGGAGGATAGACTTAATCTTAGAGGAAGCCACTGAAGGATTTTAGGATGACAAGTGCCAAAATTGTTTGGGAAGACAATATTCTATGGCTTTCCTAAAAAGTAACAAAAGCACGGATCATCATCTTTGTCCTACAGATGCCTGAAATAATGTCAAACAAACACCCAAGACAAGGAGTTTTAGTATCTCTTGGGGTGGACCCAAATGCCTCCCACATGGCTCTGCTGAGAGAGACAGAGAGCCTCATCTACCCAAAAGCAACCAACTGGCAACCTCTCCTATCTGGAATCAGGAAGAAAGCAAAAAGACACTGAGACTTCAAAATAAATATGGCTGTTCTCAACTCTGCCTTTGTGACACATGAAAATGTCTTGATTTTTTTTAAAATGAAAAAGAGTTGTAGCTCCAACTGGGGAAAATTACGCATAATGCAGTGTATGCCCACGAGAGTGAGTCTTGCATGTGTCACAGTAGAGAATAGTTGGAAACTGCTATTTTCCCCACAGAGAAGCTCCCAAGGCCTTCACTCAGAGTTTTTTTTTTTTCAAACATATATTTCCAAAAAGTTTGATATCTTCTTTTCAAACCCAGAAGGATAGAAATCACATTTAGAAGGTGCACATGAGGCTGCTACAGACGGGCCCTCTGAGCGCTGGACAACGGTGAGAACTGTAGCTGGGGCTAACACACATTGAGCATTGCTGACTGCCAGGTACATGCTGAAGTGACTTTTACATGGTGCTTTCCTCACAATCACTCCATAAAGTAGACTTGATTATTTCCTGATTTTATAGATGAGGCCATTCAGGCTTAGAGATTTAAGGAACTGACCTAAGGTCCCAGCATGGCAAGGTTGCAAAGCAAGGTTTGAACCAGGACTGTGGGACTCCAGAGCCTGGATTCTTACCTGTAACTTTCCTGCGTTTCTAATGAGTTGGAGCAAGTAAGGAAACACAGTAGTTCTTAAAAGCAGAAGAAATATTTTTTTTAAACGATAGCAGTCGGGAAGCATTTGGTGGAGTGGCAAACAGCTGTCTAGTTTTCTATTACACCAGAACGCAGCACAGCAACCGACATTCTTAATGGTAAGTCCCATCAACAAAAAGAGGAGAGATACTGCCGCAGAGGAATTCAAGATGAAAAGAAAATGTATTCTCATATTTTATATTCACTAAAATAAAAGAAAGACACCACACTAATGGAGTACCAATGCTATTGTAAACATATCGAATTAGTAATTGTGACTATTATACCATTACTTTCCATTTGCCATCCCTTAACTGAGAGAAACTTTTCAAGAGTTCCTCTCACACAATTTCAATGATGTTCTCATAATGTGTTTGGCTTTGTCGCACATGATATGCATACAAAGAGGCATTTTTTCTGTGTCTGGAATTTGGAAAAGATTGTGCTTTGCATATGCTTAATTTGAATGATGCCTATAGGAAGTAAGCTAGACTTCAAAGGGGGAAGATTGGCATTTGGAGAAGTACAGCATGCACTGCATTTAATGTGTATATCAGGACAAAAAATATTAATGAGAGAACACACACAGTTTTCTTCCTCCCCGACCAGCCAAATTCTCCACCCTCCAGCCCCATTCAAATAAAGGAGAGAAGAGTCTTTCTTGGTGGATAAGAAGCTTGATTGTTTTACATAATACAAGAATAGAGAAAAAAGCGGGAGGTGGGGAGGTGAGAGGGAAAGGAGAGCCTGATGAGCTCAACAGGAAGTGAGTATAGACAGAGAAGAGAAGACCAAGGACTAAGCCCTGGGACCCTCCTTTGGTAATAGGTCAGAGAGAAGAAGAAAAGCAAAGAAGCCTCAGAGAAGTAACCGGTAAGGTAGGAGGAAAACCAAAGAGCATGGTGTCCTGGAAGCTCAGTGAAGAACTGGATCAAGGAGGAGGAGTGACCAGCCAGGTCAAAAGCTACTGATGCATCAAGGAGGATGAAGACCAAGAACTGGCCGTTGGGATTTAACAACATGAAGGTCATTGCTGGTCTCACCAAGCAGTTTTGGAGGAGTGATGGGGGCCAAAGCTGATTGGACTGGGTTTAAGAGAGAAAGAAAGGAAAAGAATTAGAGACAGTGGGTGCTGACAATTTTTTTAAGGATTTTTGCTGCAAAAGGGAGCAGGTAAGTGAGATGGAAGCTGGAGGGAGAAATGAGGTCAAGGGAGGGATTTTTAAAGTCAGAGACATACAGCATTTTTGCATGCTGGTGGGAGAGACGAATAGAGAGAAAAATGTATCATGTAGGAAAGAAAGAGCAGAATTACTAGAACAATGCTTTTGATTTGGGGAGAGAAGATGGACCTGGCATGCTAAGTGGAGGGATGAGCCTGGACTGGATGCACAGAGGCTCGTCTGAGGGAAGAGGGGACGGGGAAGATGGGTGCAGATGCTGGTAGGTGAAGAGAGGTGGTGGTGGGAGTCTGTGGAAGTTTTCTTCTGACTGTCTTCTCAGTAAGCAGAATGGTAAGTGATAGCAGCCACAGAAGGGGCATTTCTCAGAACCTTATCAAAAAGTGAAAGAGTGAGTTTGGAAGCAACTAAATCATAAGAATGCAAAACATGTTCTTTATTCCAACAG
Seq C2 exon
AGGACTACCAGGAACTCATTGAAGACATAGTTCGAGATGGCAGGCTCTATGCATCTGAGAACCATCAGGAAATACTTAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175356:ENST00000520467:20
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.012 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0043115=CUB=PD(41.8=88.5)
A:
NA
C2:
NO
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development