HsaINT0167572 @ hg19
Intron Retention
Gene
ENSG00000146872 | TLK2
Description
tousled-like kinase 2 [Source:HGNC Symbol;Acc:11842]
Coordinates
chr17:60683491-60685509:+
Coord C1 exon
chr17:60683491-60683602
Coord A exon
chr17:60683603-60685401
Coord C2 exon
chr17:60685402-60685509
Length
1799 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAGT
5' ss Score
11
3' ss Seq
TGTTTGTTTTTATGTGACAGCCT
3' ss Score
6.41
Exon sequences
Seq C1 exon
GTATTTACCACCAGAGTGTTTTGTGGTTGGGAAAGAACCACCAAAGATCTCAAATAAAGTTGATGTGTGGTCGGTGGGTGTGATCTTCTATCAGTGTCTTTATGGAAGGAAG
Seq A exon
GTAAGTTAGAAGGTTGATGGAGAAGCTTGATCTCTTTCTTGGGTGGCACACACACACACAGTGCCTTGGTATGGATTAGTCTATTGGAGTTAATTATTGGGTTATACAAAATAGAATCCTGAAAGGAGTGGTTTAAAGAAAATACAGACTTAATAATACAAGCCTTATTCGTAAGCAGAAATCCTCAACCCTAGGGCACCTAATGAGTTCTGCGGGGCTGTTAAAAACATGCACTTTTGCTGTTCTCAATTAGATCTGGAACATGTATTTATTCTGATAGTGTGTATAGGGATTTACAAAAATCGTTTATTTATTAAAGTATACAATCTTCCCAAGAACCTGGGGGCCCCAAGAACCAAAACTCAAAATATCCCCAGAATCTTTATCGCCAGCCATCCCATTAGTTGAACCTATTATTAATGAAAGCGTGCTTTATATTTCTATACTGGGGAGATGGTGTCAGGATGTATTCATTGTTACCTCTGATCAAGGTGACATATTTCAACAAGTGGTAAACTACACCTAATGAATTGTCACATTTGTTTTTCCTTGTGAACATGCCTTATAAATGTATATATTAGGATCCATTTGTGTATTTATGTTCCTATTGCTGTTTTTGTGTGTTTGTTTGTTTCAGTGTTTCCCAGTAGGCTGTGGGTATAAGCCAGATGGGAGTTCTGTGTGTCCTTTGAATTCTTAATATTTTGATTACATTCCCCAGACCAGGCTCTTAATTCAGATTATACCTTCCTCTTTAGCTTCTCCTTGGTCTTTTTTTTTTTTTTTTTTCTATCTCACCTCTCTAAAACAGGGAAACTATTCAGAGGTAGTAGGCTTAATTATTATTTACATTCCCTGACAATGTTGAATTGCTGCCGATAACAGCAGTAGAAATTATCTAGAAATAACTGTTTGAGAGAGATCTCAGTAGAACCAGTATAGAGAGACTTGAGTTGAACTTGTTTTTAAGAGTTTATTAGAAAATGGCAGCTCGGTGACCAGGCGTGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACAAGATCAGGAGATCGAGACCATCCTGACTAACATGGTGAAACCCCGTCTGTACTAAAATTACCAAAAAAAAAAAAAAATTAGCCGGGCGTGGTGGCGGGTGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCATGAACCCGGGAGGCAGAGCTTTCACTGAGCTGAGATCATGCCACTGTACTCCAGTCTGGGCGACAGAGCGAGACTCCATCTCAAAAAAAAAGACAAAGGAAATGGCAGCTCGGCATAGTTGAAGCCATTAAGTAACCCCAACTCTTTCTTTTTCCCACTCTGTCCTTACCCCTCTTGGTTTTGACTTCCTTTCCTTCTCTTTTTCTGTTTTTTGAGTTGGCCTGAGGCACAGGTGTGTATTTCTTAGGGCCGCATGTATCCCTCAGAGCAGGTGAGGTTGCTGGGTCCTGCTCTAGATCTCCCTTTTCTCTGGTGTGAGCAAAGCTTAGCAGAGCATTAGGATATAGGAGATGCTGCTTCTGGTCCCCACTCTGCTTTGACCTGGTAGTTGAACTGTGAGCAAGTTACATATGCTCTGAGCTCTCAACCCCTTTTATCTATAAAGTGAGAGAACTAGAGGGGATTGTCTCCAGAGTTCCTTGCAGCAATTCAAATTAGAAGATGTCTTATCCTTTTCCTTCCCTGGGGTATTGAATTGTTTTCTCTATAATTTTCATCAGAGGCCTACATTATTTGTTTGTTTTTATGTGACAG
Seq C2 exon
CCTTTTGGCCATAACCAGTCTCAGCAAGACATCCTACAAGAGAATACGATTCTTAAAGCTACTGAAGTGCAGTTCCCGCCAAAGCCAGTAGTAACACCTGAAGCAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000146872-TLK2:NM_006852:20
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
No protein impact description available
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(13.2=100)
A:
NA
C2:
PF0006920=Pkinase=FE(12.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Rat
(rn6)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTACCACCAGAGTGTTTTGTGGT
R:
TTGCTTCAGGTGTTACTACTGGC
Band lengths:
214-2013
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)