HsaINT0171696 @ hg19
Intron Retention
Gene
ENSG00000131323 | TRAF3
Description
TNF receptor-associated factor 3 [Source:HGNC Symbol;Acc:12033]
Coordinates
chr14:103352526-103355971:+
Coord C1 exon
chr14:103352526-103352606
Coord A exon
chr14:103352607-103355896
Coord C2 exon
chr14:103355897-103355971
Length
3290 bp
Sequences
Splice sites
5' ss Seq
GAGGTAGGG
5' ss Score
7.81
3' ss Seq
ACGTCTCTTTCCCGTTGCAGTTG
3' ss Score
10.22
Exon sequences
Seq C1 exon
AAACACGAAGACACCGACTGTCCCTGCGTGGTGGTGTCCTGCCCTCACAAGTGCAGCGTCCAGACTCTCCTGAGGAGCGAG
Seq A exon
GTAGGGGCGGCCGGGCCCGGCCGGGAGTCTGTGGAGTCCTCAGGGCTGCGTGCCTGGCTCCCCTTCCCTGCATAGCCGAAGCCTCACGTTTTCCCAGTTCGTGAGAGTCATGTGTATGGCAGACAAACAAAAACCACAGCAAAAAGCCTTATGCCATTTTTTGGAAGTCAGAAGCAAGCATTAGGGTTAAAAGCTACAGTGTATGGCCGGGCACAGTGGCTCACACCTGTAATCCCAGCACTTTTGGAGGCCTAGGCAGATGGATCACCTGAGGTCAGGAGTTCAGAACCAGACTGGCCAATGTGCTGAAACCCCGTCTCTACTAAAAGTACAAAAACTAGCCAGGTGTGGTGGCGCGCACCTGTAATCCCAGCTATTCAGGAGGCCGAGGCAGGAGAATCATTTGAACCGGGGAGGCGGAGGTTGAACAGAGCCGAGATCACACCACTGCACTCCAGCCTGGGCAACAAGAGTTAAACTCCGTCTCAAAAACAAAACAAAACAAAACTACACTGTGGTAAATTCAGAGCAAAGATTGTGAAGCATTAAGAAAATGGGAATATTTTACATACAGTACAAGCAAAGGTGACGAGGGGTTTTTAAAGCAATTTTAACTCTATAGAATAGTAATTGCTGTAAGATTATCTCAAGAACATGAATTAACTTAGAGACACTTCAGAACCATTTTGCTCACACATGCCGGGTGGAGGACAGCTCCCACATTTTAGGGCTGCCAGAAGGGCCCCTGTGTGGCCTCTCCCAAAGGTTGCACGTCTCACATTGCGCTTGGCACTCTTTCTTTGAGACAGGTAGATTTTGCATTGACTTCACTTGATCAGGATATGTCCAGTTGGGAAAATTTCAAGGATTCTTAATGTTTCTGCATCTGTCCTGACGGGGAGCTCCTTTAGTTAGTATTCTGGGAGTCATCTGGGGCTACCCTGGGCTCCCTGGATGTGTGGTACGCTGATCTAAGGAGCCGGCTCACCTTTTCACCTCAGCATTTTTCAACAGCCTGAAATTTTACCACTGGATACTGGGTAACAGGGAGAACCAGCCTCGCATGCCCCTGACTGAGCAAGAGGGCCCATGTGGGGCTAGGGCCAGGGACTCAGGGTAGAGGAGGGCCCAGAGAGCCACTCTCCCCCAGGGTGTGCCCTCCCAGCACCTTGAAGCTGATGGGTGAGGGCAAAGTCTTGCCTGATGACAGTGGCCTCTGGGCCCTGAATCTGCCCCTGGGAGGAGCTAGGGAAAAATAAATGTAAATTATTGCCACAACTGGACAATCCTCTGTTAATGTATAAAGAGTCTGTGCTGTTGAAATAATTTCTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCACTCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCAGTGCATGCTCTGCCTCCTGGGTTCACACCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCTGCCACCACGCCCGGCTAATTTCTTGTATTTTTTAGTAGAGACGGGGTTTCACCTTGTTAGCCAGCATGGTCTCCGTCTCCTGACCTCGTGATTTGCCCGCCTCGGCCTCCTAAGGTGCTAGGATTACAGGTGTGAGCCACCGCGCCCGGCCAATAATTTCTTATTTAAAACATTGTTAAACCTGCATTTCTGTTGGGTTTCTGATGAAAGGTGCTTTTGAGCTATAGATTATTCTTGCCCCTATTCCAGAGATCCTGTAGATTCCCCGAGACTCAGAATACTGATAATAAAACCAATTTAGAAAAAGACCCAACACCGAATTTACTCTAGTACACTGAAAATAACATACATCAAACCCAGTGTGTCAGTGTGTCCCTGGCTTAACATGTAATAGCGTTGACACTCAGGTTTGTTATTGCAGTAATGACACTGGAAGAATACATTCCAAGTTTTTAAATGAACCTGGTTCTGCGCAGTCTTCACACTGCGTTTCCTTGCCAGTCACCTGTCACGTGCCTTGTGGGCGCTTCCTGCAGGGGCAGCCGGTCTGGGTTCTGAGGAGCAGCAAGGGCGTCAGGCTGCCAGGTTCCTACCACCTTGACTCTGCCCTGGCTCTGAGACCTTCCTTGAAGGTTGACCCTAGCAGTGGCCGCATGGGCCCCTCAGTCCCTTCCCGCAGTGTCCCTCCTCCTTAGTTTCGCAGCAGGGATCCATTTTCCCCTCTGTTGTAAATATCCACCTAGAGGGAAGGACCGCCTTTGTCCTGGTAGACTGAGAAGTTGTAGAACTTAGCTGCGCCCTCCAGGAGGATGTGCTCTATGAGCCTTGGGAACACATGCATGCTGGCACACAGAAGAACACATTCCCGGCTGCTGCACCCACACACCCATCCTCCCAAAAAGAGTCTGTTTTCTGTGAAGAAGATCTATCCCTAGAGTTTCCTGATGGGAATTTCTTCAATAAAAGACAAAACTTCTGCTCAGTCTTGGGGCATGATAAAGAAAAAGACCAAACTATACCTCATTTGTATTAGCCTAACACATGACTCTAAGTCCTTAAAATGTAATCCTTTCCATTCCCTTTTCTCTTGTTAGGGCATCATAAGTAATTTTTATTTGATAACTCACCAGCATTTGAGCTGAGCAAGGGACTTTTTTCTTGCAAAACGAGTTACCTGCTCCCAGCCCCACCTAATTTTCCTGCCATCAATTAGAGTTGACAGTAGTAAGAGTGTATGGTTAGACTGATCTTAGAGGTCTTTGAAAAGCTACCTGAGTTTCTGGCCCTTACAGAGGGAAAAAGTCTTTTCAGATGAAGGAAAAACTCATCTGCACTTATCTCAAGTATTATGAGTAATGGTACATTGTGTAAGCTTGCTTTGAAAATATATTTATTTTTGTGTACCGTATATTAGGTGTGTGACCCAGTTGCATTCTGAATGCTTTCTATTTTTTTGTGTTTTCATGCAATTTTTGTTTATGGTCTTTAAATGTGCATTTCAGTTTATGTTTTTTCTTTCTTTTTTAAATTCTGGCACTACAGATGGCATGTCACATTGAACAATTTGTTCTAAAGAAACTGGAAGTTTAAGAAATGTTATAGTAAATGTATTCTTGTATATTGGCGTATATGTGTATACACGTGACTAGACCGTATATTTACTGCATAGAAGTCTAGGCAGCAGATGATATATACACACCTGTAGCGATAAACACCATTCTTAATAGTACAGCTCAGATGCTATCTGTGCCCTAATATGTTTGAACATTTTCATGCAAACGTTTGTGCCACAACTCACGTCTCTTTCCCGTTGCAG
Seq C2 exon
TTGAGTGCACACTTGTCAGAGTGTGTCAATGCCCCCAGCACCTGTAGTTTTAAGCGCTATGGCTGCGTTTTTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000131323-TRAF3:NM_145725:7
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0217613=zf-TRAF=PD(1.8=3.7),PF0314511=Sina=PU(15.4=37.0)
A:
NA
C2:
PF086146=ATG16=PU(6.2=28.0),PF041569=IncA=FE(12.4=100),PF101744=Cast=PU(0.7=4.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)