HsaINT0172233 @ hg19
Intron Retention
Gene
ENSG00000121060 | TRIM25
Description
tripartite motif containing 25 [Source:HGNC Symbol;Acc:12932]
Coordinates
chr17:54978780-54981849:-
Coord C1 exon
chr17:54981616-54981849
Coord A exon
chr17:54978940-54981615
Coord C2 exon
chr17:54978780-54978939
Length
2676 bp
Sequences
Splice sites
5' ss Seq
GAGGTAGGT
5' ss Score
9.65
3' ss Seq
AACCCCCTGGCATGTTCCAGAAA
3' ss Score
4.98
Exon sequences
Seq C1 exon
ATGACTGCAAACAGAAAGGTGGAGCAGCTACAACAAGAATACACGGAAATGAAGGCTCTCTTGGACGCCTCAGAGACCACCTCGACAAGGAAGATAAAGGAAGAGGAGAAGAGGGTCAACAGCAAGTTTGACACCATTTATCAGATTCTCCTCAAGAAGAAGAGTGAGATCCAGACCTTGAAGGAGGAGATTGAACAGAGCCTGACCAAGAGGGATGAGTTCGAGTTTCTGGAG
Seq A exon
GTAGGTCGCCACAAGGCATTGTTGAATGTTTTTTTTTTTTTTTTGCCTGATGTCATGCTGTTGATGATAGGGCCCTCAAGGAGCGGGAGACTGGAAGAGGTCACTGGAAGCATCCCTGAGACACACGCTGTATTAGTTTTCTGAGCTGGGCAACAACTTACCACAAATGTAGGGGCTTCAAAAAACACATATTTATTCTCTCAGAGTTTCTCTGGCTCAGGAATCTGGACATGGCTTTATGGGTGGCCTGCATAGGGTCTCACCAGGCTACAGTCTGCGAGGGATGGCCAGGCTGTTTCCTTTGGAGCTCAGGGTTGTCTTCCAGGCTCATGTGGTTGTTGGCAGAATTTAGTTCCTTATGGTTGTAGGACTGAGGCCCCCCGCAATTTCCTGCTGGCTGTCTCTCAGATTGATAGCTGACTTCTTCAAGGCCAGCATGAGAATTTCTCCTCTAGAAAGATGCAATCCCTCTTTTAAGGTCTTTTACCTGATTAAGTCAGGCCCACCCCAGATAATTGCCCTTTGATGAACTCAAAATCAATTGATTTGAGATGCTAATTACACCAGCAATATTCCACCCCCTTTGCCACATGACATAACCTAATCACAGGAGTGATATCCTATTTCATTCACCGTCCTGCCGATACTGAAGGGGAGGGCATACTATAGGGTATGTACATCAGTCGGGGTCGGGGGCTTGAGGGCCATCTTAGAACGTTGCCTGCCACTCACACTCCACCTCTTCCTCCCATCCTTCCTCCAGCAGCTCCTGGAAGTGTGTGTTAGTAGTCCCTTTTGCATTGCTATAAAGGAGTACCTAAGACTGAGTTATTTATTTATTTTATGTATTTATTTTGAGATGGAGTTTCACTCTTGTTGCTCAGGCTGGAGTGTAGTGGTGTGATCTTGCTCACTGAAACCTCTGCCCCCAGGCTCAAGTGATCCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCGCACGCCACCATGCCCAGCTAATTTTGTATTTTTAGTAGAGACGAGATTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCCACCCACCTCGGCCTCCCAAAGTGCTGAGATTACAGGTGTGAGCCACTGCGCCCAACCAGACTGAGTAATTTATAAAGAAAAGAGGTTTATTTGGCTCACAGTTCTACAGGTTGTACAAGCATGGCACCAGCATCTGTTTGGCTTTTAGTTAGGCCTTTGGTGAGGAAGGAAGCTTTTACTCATGGCAGAAGGTGAAGCTGGGAGCAGGCATGTCACAGGGTTAGAGAGGGAACAAGAGACAGAGGAGGAAGTGCCAGCCTCCGTTAAACAACCAGTTTGTGCAAGAACTCACCTGTTACCATGGGGAGGGCACCAAGCGGTGCATGGGGAATCCACCCCCACGACACGAACACCTCCCACCCTGCCCCACCTCCAACACTGGGAATCACATTCCAACATGAGATTTGGAGGGGACAAACATCCAGACTGTATCAAAGTATCTGTCTAAAGCATGGGCCCCCTGCTGTTTCTGGCCTCATGTCCCTTAACATGGCCTGCAGGGTCCTAGGTGACTGGGCCCCGCCTGTGCCAGCAGTCTCATCTCATATCATCCATCCCTGGCTCATGCCCTATGCACTCACTGTTCCCCAGACACAGTGGGTGTGGGTGGGATGCCATGCTGGGCATTCTTGCCTAGTGAGTCGTATCCTTCCAGGGCCTTGGATCCCATTGCCATGCCGTATCGGTGTTCCCAAGCATGCCACACTGTTTCTACAGTAACATTGGGTGATGTTGTTTCAGATGTGCATTTTTTCATGGCTGTTTTGACTGTAAGCCCATCTCTTATTACCCCCATTCATCCTCCTGCCAATCTGACCAGCACATAGCAGAGTGCTTGGCATATAGTGGTGTGCCCCATTGATTGAGTGACCTGCAGCTATACCTGAAAGACCCAGATTCCTTGTTCAGATCAGGGGGTGGGGAGACAGTGCAGGAGTGAATGGGAACCTTGTCTCTGTGCACTGAGGCCTGATGCGTGCCTAGTCTGGATGGCGTTAAGTTTCATCCCAAGTGTTCATTCCTGTCTGTTGGAGCAGCTGCCCCGAGCTCTCGAAGGATCTGAGTGCACATCTAGGCTTCTTGATACTGTACAACCCTATTTTTCTCAAAGTTTGGGACTTCCAGGAAGACCCTCCCTTCCCATAAGATATTCCCTGGCTGCAATCCACATCCCTTGAGATGTCCCTGTCTGTTACCAGAATGTGTGATTAGAGCTGTTCCCCTAGGATTGGGGTGGTCCTGAGTTTCCTGTGCTTTTCCACCTTTAGCTGGAAAAGTGGAAAGAACATTGTCCTGGGGGATCGGAAGATCTCAGTCCCAGCTGTGTCTGTGCCCCTAGCTGGTGGAGTTCCTGCCATGTCTAGACCTCAGTTTCCCCATCTGTAAGATGAGTGACCTCTGGGGTCCCCTCCAGCTCCAGATTACTGTGTCTTCAAGTGTCATTTAAACTCCTGGTGACCTCTGGCCTGTAATTTGAGAAGGCCAATTGGACTTAGCACTCTTGGGCATAGGGGAGAGCCTCCTGGGGTTGGTGAGGACTGAGCCCAGGTCCCCGTTTCACCAGAGCTGCCTGCACTAACCCCCTGGCATGTTCCAG
Seq C2 exon
AAAGCATCAAAACTGCGAGGAATCTCAACAAAGCCAGTCTACATCCCCGAGGTGGAACTGAACCACAAGCTGATAAAAGGCATCCACCAGAGCACCATAGACCTCAAAAACGAGCTGAAGCAGTGCATCGGGCGGCTCCAGGAGCCCACCCCCAGTTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000121060-TRIM25:NM_005082:3
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.295 A=NA C2=0.315
Domain overlap (PFAM):
C1:
PF0003816=Filament=PD(58.1=96.2),PF033408=Pox_Rif=FE(48.7=100)
A:
NA
C2:
PF033408=Pox_Rif=PD(25.9=75.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)