HsaINT0174173 @ hg38
Intron Retention
Gene
ENSG00000123607 | TTC21B
Description
tetratricopeptide repeat domain 21B [Source:HGNC Symbol;Acc:HGNC:25660]
Coordinates
chr2:165929135-165929747:-
Coord C1 exon
chr2:165929650-165929747
Coord A exon
chr2:165929336-165929649
Coord C2 exon
chr2:165929135-165929335
Length
314 bp
Sequences
Splice sites
5' ss Seq
GCGGTACAG
5' ss Score
3.82
3' ss Seq
GAAAACTACTTATTTTCTAGGAA
3' ss Score
7.5
Exon sequences
Seq C1 exon
GATTTATCCAATGTCAGTTGATAGAAGGGCAATTACAGGATGCAGATCAGCAGCTAGAATTTTTAAATGAAATCCAGCAATCCATTGGAAAATCTGCG
Seq A exon
GTACAGTATTTTATTTTATCAGCTGGTAGATGCTAGCTGTTTATAAAATATGAAATTATTAATCAGTCTTATTGTTTTGTAATGGCTGTAAAGCACTAGTGTACACTAATTTTAATATGTAATTGCATTTATTTACCTCCATTCAAAACTAAACTTTATTCTTCTGAATGATTCTAAAAGTCTATTCAAGCTAATACTTGAGTTTGAACAAATAATTGCATATCAGTAGCACATTATATGCATTTGAAATCTAAGTGGAAATAAATGGCTTTATAACTAAATGGAATAATTTATGAAAACTACTTATTTTCTAG
Seq C2 exon
GAATTAATCTATTTACATGCAGTTCTTGCCATGAAGAAAAATAAACGACAAGAAGAAGTTATTAATTTGTTAAATGATGTCCTGGACACTCACTTTTCACAATTAGAAGGTTTGCCTCTTGGCATACAGTATTTTGAAAAGCTAAATCCTGATTTCTTGTTAGAAATTGTTATGGAGTATCTGAGCTTCTGTCCAATGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000123607:ENST00000243344:10
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF145591=TPR_19=PD(47.4=81.8)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATCCAATGTCAGTTGATAGAAGGGC
R:
CTGCATTGGACAGAAGCTCAGA
Band lengths:
294-608
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains