HsaINT0174176 @ hg38
Intron Retention
Gene
ENSG00000123607 | TTC21B
Description
tetratricopeptide repeat domain 21B [Source:HGNC Symbol;Acc:HGNC:25660]
Coordinates
chr2:165917257-165919433:-
Coord C1 exon
chr2:165919276-165919433
Coord A exon
chr2:165917482-165919275
Coord C2 exon
chr2:165917257-165917481
Length
1794 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAGT
5' ss Score
11
3' ss Seq
TATTAAATATTATTCTTCAGGTG
3' ss Score
8.9
Exon sequences
Seq C1 exon
GTGATATTGAAGCAGCTTTCAATAACCTTCAGCACTGCTTAGAACACAATCCCTCTTATGCTGATGCTCATCTGCTGCTAGCTCAGGTTTACTTGTCTCAAGAAAAAGTCAAATTGTGTTCTCAGTCTCTTGAACTTTGTCTGAGCTATGATTTTAAG
Seq A exon
GTAAGTATTCCAGACTGAAGTGGATAAGACATATCACCCTCCTTGAAAGCTTACATATTCAAGTATTTTGTGTTTTAGCCTGTAGTATTTTGCTAACAGTTGCATTTTTAATGGAAAAAAAAATGGAACTCACAAGCAGTAGGAGGAAAAATTGAGGCAATTCAGGTATGGGTAAAAAACTATGTGGACTTGGTGACAAAAATCCTGAGGTTAATGTCTGGTCTTTCACTTCTCTCTGAGCCTCAGTTTTCTTTTCTGTAAAACTCATTTACTAATACTCTGCTGTTACAATGAGAATTAAATGCAATAATGAAGGTATATAAAAATGATGATCCTTATGTCAAATATTTTTATGTATAAAGATAATAATTGTCTGTTTATTTCTTGGACCTTAGTTTTTAATAACTTCTTTTTAGATTCATTGTGAAAGAACATCTTGTCATTTTGAAAGTAATTTTGTGGTTTGAGGATATAAAAACACAGTACTTTTCTATCCAAGATATTATGTGTTATATCCAGTATCCCCTCAACGTTAGGGAAAATCCTAGGTTCAGTTGCTTCCTGAACTACCTCAAGTCATGGAGGAGCTCTGAAAACTTCTGCTTTGCTTCACAGGGTCATGGACCCTGTTAAGAGAGAACCCTTCAGTGAATTAGAGAATCCTAATTAAGATTTGCAGAAGGCCGGGCGTGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCAGATCACAAGGTCAGGAGATCGAGACCATCCTGGCTAACACAGTGAAAACCCGTCGCTACTAAAAATACAAAAAAAGTAGCCAGGCGTGGTGGCGGGTGCCTGTAGTCCCAGCTACTCGGGAGACTGAGGCAGGAGAATGGCGTGAACCTGGGAGGCAGCGCTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGCGAGACTCCATCTCAAAAAAAAAATTGCAGAAAATATCACCTGCTTCTTATGATAGTGGTTTTCAAGACTAGTGGTATGTCAGAGCCTCAGTGCTGGTGCCCCACCTTTACTGAGTCAAAATCTCTGAGGAAGGAGCACAAGCGTGAGTCTCACACGAAGCTCTGTAAGCAAATGTGCAGGCTGCCTAAGGTTGAGAACCTCAGCATCAGGAGGATTATAGACTTCCTAATCGCTAGGTGGCTGCCACGTCACCTCGTTCTGAGTCCTCTCCTTCCCTTTGACTTCTTTTTCCCACCTCATTTTTATCATTTTCTTATGTTTTCTGTATATACTGTTGATAGCCAACGTAAAGATGGAAGCTTCAGAACTACATATTTAGGAGTAGTGTCAAAGGGGAAGGTCAATGTTTGATTAAAATGTCCTGAAACTTTTAATCTTCAAATTAAAAAAATAAAGGGGAGAAACAGTGTTTCTAGAAATCTAATAACTTCATATCAGTTGTAGAAGTGCCAGATAAAGAAATTCTTTTCCTGAAAATTCAAGTAATCTCTTAGAATGTATTTGCTAGCCTTATAAAGCTTGTTTGCACTTTCTCTTCTGTCACAGTAGAAATATGTAATCAACCTCTTTGTCATCTCAAAGGATGCAGGGAGAAGCAATTTTCCTGAATCCGATTTAATGTGATACATAATCAGAGGGTTAATAAGAGGGCAGAGATAGACCTCATGCATACAATCAAAGATGGACTGTTCTCAGTGATCTCATTATTTTAATGTTTGATGGATTGTAAATTATGTGTTGATGTTGTAAGCACTCCAAGGAAATATTAAATATTATTCTTCAG
Seq C2 exon
GTGAGAGACTATCCTTTATACCATTTGATAAAAGCTCAGTCACAAAAGAAAATGGGAGAAATAGCAGACGCAATTAAAACACTGCATATGGCAATGAGTTTACCAGGAATGAAAAGAATTGGAGCTTCCACAAAATCAAAAGACAGAAAAACTGAAGTTGATACAAGCCATCGTTTATCGATCTTTCTTGAATTGATAGACGTTCACCGCTTAAATGGAGAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000123607:ENST00000243344:13
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.120
Domain overlap (PFAM):
C1:
PF134141=TPR_11=PD(78.1=94.3)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCTTCAGCACTGCTTAGAACACA
R:
TGCTCTCCATTTAAGCGGTGA
Band lengths:
357-2151
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains