HsaINT0174177 @ hg38
Intron Retention
Gene
ENSG00000123607 | TTC21B
Description
tetratricopeptide repeat domain 21B [Source:HGNC Symbol;Acc:HGNC:25660]
Coordinates
chr2:165915201-165917481:-
Coord C1 exon
chr2:165917257-165917481
Coord A exon
chr2:165915440-165917256
Coord C2 exon
chr2:165915201-165915439
Length
1817 bp
Sequences
Splice sites
5' ss Seq
CAGGTAGGT
5' ss Score
10.28
3' ss Seq
TTTTAATTTCATCTTTACAGCAT
3' ss Score
9.12
Exon sequences
Seq C1 exon
GTGAGAGACTATCCTTTATACCATTTGATAAAAGCTCAGTCACAAAAGAAAATGGGAGAAATAGCAGACGCAATTAAAACACTGCATATGGCAATGAGTTTACCAGGAATGAAAAGAATTGGAGCTTCCACAAAATCAAAAGACAGAAAAACTGAAGTTGATACAAGCCATCGTTTATCGATCTTTCTTGAATTGATAGACGTTCACCGCTTAAATGGAGAGCAG
Seq A exon
GTAGGTCAAGTTTTAATTTAAGGGCTCGGATGTGAACTTTCTTATTCTAACATATATATTAGTAGAAAATGAAAAGCTGCCCAGGCATGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGATGGATCATCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAATATGGTGAAACCCTGTCTCTACTAAAAATACAAAAAAATGAGCTGGATGTGGTAGTGCGCACCTGTAGTTCCAGCTGCTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTAGGAGGCGGAGGTTGCAGTGAGCCGAGATGATGCCACTGCACTCCAGCCTGGGTGACAGAATGAGACTCCATCTCAGAGAAAAAAAATGAAAAGCTAAATGTATTCCCTTGACCAGGTGGTAAACTTTAGAAAAATTTAATTTTCATTACCTTGCACTAAAAATAAACTTCCTGTAAGCCCCTGAAAGTTAAGCATAATTTGCTCCTGGTTGACCTTAAGTATCAGTGTGCTCATGTTGGCTACAATGGAACATAATAACATGATGTACAACTCTCTTGGTTACCATGAATGTAATAATATAATGCAGTTATAATCCTATGAATCTCTAAAAAGATTTATACACATAAACACAAACACACATTTATGCACACTCCAGAACTACTGAAATAAAAAGGAAGTACCAACCTGAAATTCTAGTAGATGAGGAGACAAAATACTTGATGAATACAGCTTTGGTAAACTCATAGGAATATTATAAAGTCAGATATTTTTAAAAATAATAATATATACGATAAGATAGAAAGTAATTCTGGGAGAATTACAACTTTGTAGAAAATGAGGAACTCAAAGTCATTTGTATCCGTTGTTTTAGGTTGCAGCACTTGCTAATCACTTATTTTTCATATTTTAATGAAAATTAAGAAGGCTGTATTTCTAAATATTTGCCAAATCACAAAGAATTTCCATTTATTTACTGTATTTTTTAGTGATAAGGTCTCACTCTGTCTCCTCAGCTGGCATCCAGTGATACAATCATAGCTCACTGCAACCTCAAACTCCTGGGTCCAAGAGATTTTACCATCTCAGTCTCTCAAGTAGCTGGGCCATGCCCAGCTAGTTTTTAAAATATTTTGTAGAGGGTCTCCCTATGTTATGCAGGATGGTCTCAAACTACTGGGCTTAAGTGATCCACCCAGCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGAGAATTTCTGTTTTACTAGTTAACTTAAAGTACATTTAACAAGTAAGGCCAATTATACCCTATAAAGTTGATTCTGAGGTACACTTAAATTACATTTTAACATTTCTGGAATTCTTATAATCTCTGAAGTTGAGATGACTCTTAAATGACATTTTAGATTCATCAAGGTACACATTTGGAAATGAGGTAGAATATTCACCCAAAGTGTAACAACAGTGTTCTGGTGGAGGGAATAATCTGCCACTTAATGAAGAGCCAGTGTGTACAGCTCTTCATTATTCAATGCTGGGTGCTTAGTAAGTGCTCATTAATATAGTAGCAGTGACCCTCTGTAGCAGCTGCTGTTGTCCTAGTTGTGAAAACATTTATCTAGCTAACAATATTTACAGGCTCATCTGATTTTGGTCATGGGTTTAGTTTTAAATTTTTGAGGTTTCAGAAAATTCTATCAATTTATTTCGTAAATATTATAAATGTACTAGCATTTATTCATTCTGCGTTATGAGAAAATCTCCCTTTCTAGTGTTATTTGTTCACTATTTTGGAAGAATGATTATTTTAATTTCATCTTTACAG
Seq C2 exon
CATGAGGCAACCAAAGTTTTACAAGATGCCATCCATGAATTTTCTGGAACATCTGAAGAAGTGCGGGTTACCATTGCTAATGCAGACCTTGCTCTAGCCCAAGGAGATATTGAACGGGCTTTAAGCATCCTTCAGAATGTTACAGCCGAACAGCCTTATTTTATAGAGGCCAGAGAAAAAATGGCAGATATTTATCTGAAGCACAGAAAAGATAAAATGTTATATATCACTTGTTTTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000123607:ENST00000243344:14
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.120 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF134321=TPR_16=WD(100=60.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTCAGTCACAAAAGAAAATGGGA
R:
GGCTGTTCGGCTGTAACATTC
Band lengths:
347-2164
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains