HsaINT0174178 @ hg19
Intron Retention
Gene
ENSG00000123607 | TTC21B
Description
tetratricopeptide repeat domain 21B [Source:HGNC Symbol;Acc:25660]
Coordinates
chr2:166770084-166771949:-
Coord C1 exon
chr2:166771711-166771949
Coord A exon
chr2:166770157-166771710
Coord C2 exon
chr2:166770084-166770156
Length
1554 bp
Sequences
Splice sites
5' ss Seq
TAGGTAAGT
5' ss Score
9.66
3' ss Seq
AATGTTGGTCTGATTTCCAGAGA
3' ss Score
5.77
Exon sequences
Seq C1 exon
CATGAGGCAACCAAAGTTTTACAAGATGCCATCCATGAATTTTCTGGAACATCTGAAGAAGTGCGGGTTACCATTGCTAATGCAGACCTTGCTCTAGCCCAAGGAGATATTGAACGGGCTTTAAGCATCCTTCAGAATGTTACAGCCGAACAGCCTTATTTTATAGAGGCCAGAGAAAAAATGGCAGATATTTATCTGAAGCACAGAAAAGATAAAATGTTATATATCACTTGTTTTAG
Seq A exon
GTAAGTAATTGTCTTAACCCATTATATTTTGATACATTTAGCCACTAGTATTAATTCCCAATTTTTTTTTAACTTTCTTTCAACTGCTTCACAAATACTTTACAGATCGTTTTCTGAATGTGGTCCTGATTCCTTCTACCACCAACTGCAATCACTCTAACCAAGTTATTTGCTCTCCCTAAAACATAATTATGATTCCTTCAAACTGGCTTGCTGTAGTTTCTCAGCTCTCCTTATCAAATATTATTTTTAGACCCTAGATCTTCCTGTTTGAGAAGGGAAATTGTACCCTGTGTTCTAATAACTTAAGAGCATCATGTAATATAACAATAATCTACGGGATAGGCAGGTGTATTTATTAGTCGATATAGTAGTTGTAGGAAAAAAAAAGTTATTTTAGTATGTACCATGCTAACGTGTGGATTACAGATATTTCTTGGTGAAAGAGCATGACCTTAAAAGTATGTCACACTGATGCCCTTATGAGTTATTGGGATACACAACACACACACACACACACACACACACACACACACACACACAGATTGCTCTTCCTCTTCTCCCCAAACAGAAGGGTAAACATAGAAGCATACACTCTATGTAAGAGAAAATTAACGTTTTTAGCTCTTGAGATCATAGTAAACTGTTGATGAAGTAATTCAGTATTGGCTCATCTATATTATATCAAACTCAAAAAGCTGCTCAGATTCTTTTAAGCACTGAGTGATTCAGAGAAACTGAGCAGCACCGCATGTTTAGACAGATGGACTGGAGTTCCTAGATTGTGTTTTCTAAGGTATTTCCAGAAGATTATCACTGTCATCTCTAATGATATGAAAATAATTCAAAATAGGGTTGATTTATTTTTGATGTACTATAATGTAATAGTTAAAAGTATAGGTTTTGTTTCAGGAAGATCTGACACATCAGCTGCAACTCTTAACATCATCTGTAAAACTGGGATAATAATTCTCAAGAGTTTTTGGACCAGTTAGATGAAATACTGTATGTTAAAGACTTAACACCACATTATTATTTCAATAACTTTGGTAATTTGACCTTTAGTAGTCTACATTTTCAGGTCAAATGTAAGCAACAAATACTGAAATAGAAGATTTTGTATTTTTTTAAGGTAATTTATTTCAGCATATAATTTATGCCATGAGTATCAGAGCTCAAGATGCATAGGAGGACAGTAAAATTTTATTCTCCCATCATTTTTTTGGTACCTTCACTCCCACATCATTTCAGAAGTAAACATAGCAAAATGTGTAGGTCCAAATAAGGAGAACCTAGATATTTACTATCTATCTGAACTCAGTTACCTGCATTTCAGAAAATGGAAAGATTCAGTGACAGAAATAGCTGATCTAGCATAAACAATTTGGGTGTGGGTATGCATGAGGTTTTTATAATATTACACTGTTGGGTATATAGAGATACTCTGAAGGCTACTGGCTAACTAAAATAAGGGAGCTTATTTTTTATTTTATTTTATTTTTGGAAGAAGATATCTGTGTTCAATATGCTAAGTAATGTTGGTCTGATTTCCAG
Seq C2 exon
AGAAATTGCTGAAAGAATGGCTAACCCTCGGTCTTTTCTTCTCCTTGGTGATGCATACATGAATATTCTAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000123607-TTC21B:NM_024753:15
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF134321=TPR_16=WD(100=60.0)
A:
NA
C2:
PF134141=TPR_11=PU(25.4=68.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CATGAGGCAACCAAAGTTTTACA
R:
CTAGAATATTCATGTATGCATCACCA
Band lengths:
310-1864
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)