HsaINT0174184 @ hg38
Intron Retention
Gene
ENSG00000123607 | TTC21B
Description
tetratricopeptide repeat domain 21B [Source:HGNC Symbol;Acc:HGNC:25660]
Coordinates
chr2:165899770-165901910:-
Coord C1 exon
chr2:165901722-165901910
Coord A exon
chr2:165899881-165901721
Coord C2 exon
chr2:165899770-165899880
Length
1841 bp
Sequences
Splice sites
5' ss Seq
AAGGTCAGT
5' ss Score
8.68
3' ss Seq
TCTAGCCCTTTGCTCTACAGATT
3' ss Score
8.48
Exon sequences
Seq C1 exon
GCTCGAGAATTACAAGCTCGGGTACTAAAACGTGTTCAGATGGAACAGCCAGATGCAGTTCCTGCACAGAAACATTTAGCAGCTGAAATTTGTGCAGAGATTGCAAAACATTCTGTTGCTCAGCGAGACTATGAAAAAGCAATTAAGTTTTATAGAGAGGCTCTGGTTCACTGCGAAACAGATAATAAG
Seq A exon
GTCAGTACCTTTATAAAATTTTAAATACCTTTTATTCCAGATGTCTTCTAATTTCCTCAGATGTAAAATTTTTACCAGCTTATTTTAAAAGAAGATGTAGGCAGGGTGCAGTGGCTGATGCCTATAATCCCAGCCCTTTGGGAGGCCAAGGCATGTGGATCATCTGAGGTCAGGAGTTTGAGACCAGCCTGACCAACATGGGGAAACCTTGTCTTTACTGAAAATACAAAAATTAGCCAGCGTGGTGGGGGGCGCCTCCTGTAATCCCAGCTACTTGGGAGGCTAAGGCAGGAGAATCGCTTGAACCTGGGAGGCGGAGAGGTTGCAGTGACCCAAGATCGCGCCACTGCACTCCAGCCTGGGCAACAGAGCGGGACTCCATCTCAAAAAATAAAATAAAAAAATAGAAACAAGATTTTAAAAGAAATGTAACAAAAATACAAGTTAAAAGATTAATATTATTCCTCAAAAACTTTCAAAATCTTACATGATGCCTTACATTAAGAATATTAGAGTTTAAGGCTGGATGCAATGGCTCATGCCTGTAATCCCAGCACTTTGAGAGGCCAAGGCAGGCAGATCACTTGAGTCCAGAAGTTCAAGACCAGCCTAGGCAGCATGGGTAAACCCCAGTCTACTAAAAAATACTAAAATTAGCCAGGCATGGTGGCATATACCTGTAGTCCCAGCTCCTTGGGGTGCTGAGGCAGGAGGATCACCTGAGCCCAGAAGGTCAAGGCTGCAGTTAACCATGATGATGCCACTGTACTACAGCCTGGGTAACAAAGCAATACCCTGTCTCAAAAAAAAAAAAAAAGAAAAGAAAAAAGAACATTACAATTATTTAAAAACTATAATGGAACACGTAATATAAAGCAACCTGCAAATTGTTTTAATATTTATGTTTTTAATTATCAAAATAATTTAAATAATTTTCAAATTTATTGTATCAATTTAGTTTATCAAAAATTAATTTTAAAATAATTTAAAATAATTTCTCAATCACAAATACCTGGATTTAGATAATTCAGTTCCTTTTACTAAACAGCTGTTGTACACTCTGTATTTCAATTGGTGTTTAGTACTAAGGATGCAAAAATGGCTAGGCTCAATCTATGACCTCATATAGCACAGTGGGAGAATAAATGTAAAGATAATTTTGGTGTAGCACATTTACATACATGACTGATTATATAAAAAGTTTTTACTCTGTCAAGATCTGAGAGGATTTGGAGAGATTATTAATTTCTGAAAATAATTAATGGCTAAACACTTAAGTAAGTGATCATGTACAAAAGACAACTATCCTCTAGAATTTAATAACTAGTTTGAACATTTTTATTAATATAATTTTTTCAGATAAACGGCAAAAACAACCTTTAGCAAGGCATAACCAAACAGATACCTTTTTCAGTGGTGGCTAAAGGAGTTGGAATCCTACTTTTAAATCTGAGGCATACCTTAGAGATTATCTGCTTGAAGCTTTTTATTTTACAAATGAGAAAGCAGGTTAAGGGAGGTAGAAGGGACCTGACTTGGCCCCGTTATGGGACTATAATCCAGTCTCATGGTTTTAAGACCAGTGTTCTTTTCACAATGCATTATGTCTCTCTACTTTTGAAGTGAGTTACTACCTGTTTCTCTGTTTTTTTTTTTTCTAGTGTAAGAGAAAATAGAGATGGGTATACATACTGTTGTTTTTTTTTTTTTTTTGTCTATTATACTTGGCATTTTATTGCAATGACTTTTGGTCAACTAAAGTTTAATCTGTACCCACGTATTTTCCTCATTGACTTTTTATTCTATACAGTGTCTGATGAATCTAGCCCTTTGCTCTACAG
Seq C2 exon
ATTATGTTGGAACTGGCACGATTATACCTGGCACAAGATGACCCTGATTCCTGCCTGCGGCAGTGTGCTCTACTGCTTCAGAGTGACCAGGATAACGAAGCTGCTACCATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000123607:ENST00000243344:20
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.009
Domain overlap (PFAM):
C1:
PF134241=TPR_12=PD(7.7=9.5),PF145591=TPR_19=PU(36.8=39.7)
A:
NA
C2:
PF145591=TPR_19=FE(52.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTCGAGAATTACAAGCTCGGG
R:
AGCAGCTTCGTTATCCTGGTC
Band lengths:
294-2135
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains