HsaINT0175326 @ hg38
Intron Retention
Gene
ENSG00000104833 | TUBB4A
Description
tubulin beta 4A class IVa [Source:HGNC Symbol;Acc:HGNC:20774]
Coordinates
chr19:6501515-6502584:-
Coord C1 exon
chr19:6502156-6502584
Coord A exon
chr19:6501624-6502155
Coord C2 exon
chr19:6501515-6501623
Length
532 bp
Sequences
Splice sites
5' ss Seq
AAGGTGCTC
5' ss Score
3.68
3' ss Seq
CCGACCACCTCTCTCTCTAGTTT
3' ss Score
7.93
Exon sequences
Seq C1 exon
ATTTCTGCGGGTGGCCAAGCCTGGCTGGGGGCTGGGACGGGGGAGACTGCACTGGTGGCTCCCTAAGGGGCCTCACCCCCAAGGCAGGGGTCGGAGCACGTGGCGTCCCGGACTTCTCTGGGAGGCCCCCTGGGGAGGGAGGTCCCTGCACCACCTCCCCCCACCCCAGCCCCCTCCATCATCCCGGGGCGGGACCAAGGGGCGGAGCGGGAGGGTGACCGGCCGTGACGCGTGCCCCGCCCGCTCATATAGCGGCTCCCGGGGGCGCAGGGACCGTGCTCCGCCGTCTCCGCCGCATCTTCCACCCTCGCCGCCGCCGCAGCTCCCCGCGCTCGTGCCACCGCCGCCGCGTCCACCCTCAGCGCCACCGCCATGCGGGAGATCGTGCACCTGCAGGCCGGCCAGTGCGGCAACCAGATCGGGGCCAAG
Seq A exon
GTGCTCGGGGAACGGGGCCCGGGGAGGCAGTGGCGGCCCCGGGGAGCACCGCGGGGTCGGTCCCCGGAGCACCCCGCAACCTGGGAGTCTTTGGAAAGGAATGAGGTCCCCAGGAGGCCAGCGCGCCCCAGGGGCCTTGGGGGAAGGGTCGCGGGGTGGGGGTGGCAGGGCCAGACTGGGAACAAAGAGGCTGCGGAGAGTGGGAGCCAGCCTTCTGTCCGCCTGTCACAGCTGGGCCCACAGCTGGGCCACTGTCCCCTCCTCACGCACAAAGAGCCCCGGTGCCTCCCCCGGGCTGCAGCCTGGGTGCGCTGGCACCAGCCGGCCCCGCTGGGTGCTGACTCGGCTGCACCCCGCCCCCACCGCTCCTTCTTGCTGCCTCATCCTCGCCCCGACACCATGCCTCTAGGTCCCCCGTTCACCTTGCTGGGGGAGAGGTGGCAGCTAGGGAGCTAGTTGGGGGCTGGGGGCAGTCCTCGGCTTGGCCACCGGCTTCCCCTCTCTCAACTCTTCCGACCACCTCTCTCTCTAG
Seq C2 exon
TTTTGGGAGGTTATCAGTGACGAACATGGCATCGACCCCACAGGCACATACCATGGGGACAGTGACCTGCAACTGGAGAGGATCAACGTGTACTACAACGAGGCCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000104833:ENST00000264071:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.042 A=NA C2=0.147
Domain overlap (PFAM):
C1:
PF106444=Misat_Tub_SegII=PU(30.9=89.5)
A:
NA
C2:
PF0009120=Tubulin=FE(16.2=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGACTTCTCTGGGAGGCCC
R:
CGATGCCATGTTCGTCACTGA
Band lengths:
354-886
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains