HsaINT0176811 @ hg19
Intron Retention
Gene
ENSG00000144357 | UBR3
Description
ubiquitin protein ligase E3 component n-recognin 3 (putative) [Source:HGNC Symbol;Acc:30467]
Coordinates
chr2:170783830-170785378:+
Coord C1 exon
chr2:170783830-170783915
Coord A exon
chr2:170783916-170785236
Coord C2 exon
chr2:170785237-170785378
Length
1321 bp
Sequences
Splice sites
5' ss Seq
CTCATATCC
5' ss Score
-13.36
3' ss Seq
TTTCTTGACATATATATCATATT
3' ss Score
-3.24
Exon sequences
Seq C1 exon
GAATGTCTGATGATGAGATTCTCAGGGCCGAGATGGTAGCCCAGCTGTGTATGAATGACAGGACACACAGTTCATTGCTGGACCTC
Seq A exon
ATATCCTTTTAAAATTTTACTTTCTGTTAGTTGCAGGATCTAAAATAAGTATTTTTTATGATTAATAGTTTATCAATTTTTTGATTAATTTTTTTTCAAAGTTGAAAAATAATATAGAAAAAGAAGAACACCAGTTGTGTGCTCAAGTATGTATTCAAGCCTGGTGACTGTTTTTTTTTTTTTTTAACCTCCTGTTATTACCTCTTGGGGAACTCTTCTTAGACTTTAGGGTAGATTTCAGGACTGAATGATGGCTTTGGCCACCCCAGCATTTAACCTCCTAGTGGACAGCATTACTGAACGTTTTATAAAAGGCAGCTAGGTCCATTTTGTCTGTGTAGCCAGGATGCAATTCATGGTTAACAGTTAAAGGTATACCTTACGATTATTATTACCAGGATTTTAAACATTTTGAGGGTTTTTCTGTAGAATTTGGTCTTAAAGGATTTTTGAATTTATAGATTTTTGTGTACAAACAGGGAACCTGTGGTTCTTTGTATAGGACTGAACATACAATGAGAATCTGATTATCTTTTTAAGTTAATGTTAATAAAATTTTACACAAAGATTATCAAGTAATTTTGTGATAAAAATTCTGGCCGAATTTAGTATTTGTATATCTTATGACTATGTTTGGAAGAATTGGCTAAACTTTTTATTTTGTGAAATAAGTCCTATTAGAATGCCTGTTTGACAACCTTGATTTTTGTAAGCAGCCTCAATTTGATACTGTCTGATGATTTCCTTCAGTCATTATGAACTATGTGTCAGTGCTATTATAGAGTAAAAACGATCTCTGTGTCTTTCAATTTTAAAGATTTATGTGCTTTAATGTGAGGAGAGAATCTTTTTGGTTTGCCTCTTTGCTTATATTTGCTTAGTATTTTTTTCTTTGGGGATGAAATTTTGTGTTTTTGGAAAAACAATCTTTGCTCATAAAAATCTTGGCTAATTTTTCACAAGTTCTTTCTGTTTTTTAAGGAAAAGTTATTTACAAAATGGTAAAAATGAAGACACATTTTTAAAAGTTTTTCTATCGTTTTCTGAAATTTGATAAATTTATTTCGGGGAAAATATACCTGGGAACTACTGCAGCATACAATTTATTAGTAGGCTCCTAGATTAAACATATTTTCAAAAATCACAATTAAAAACAGTTATTATTGATCTGTTGTATTATATAGCCCTCTTGTGGCCAGCTTTGTATATTACAACCAATTACTATTTGTCTACTTCAGCAAAATGAGAAACTAGAGTACCTTGGAAAGGCTATAAATCTGGCTTTTTGTTACTAATATTTTTTTCTTGACATATATATCAT
Seq C2 exon
ATTCCAGAAAATCCTAATCCCAAAAGTGGCATTATTCCAGGCAGTTACAGCTTTGAATCAGTTTTATCAGCTGTAGCTGATTTTAAGGCTCCTGTTTTTGAACCTGGAGGTTCTATGCAACAAGGCATGTATACTCCCAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000144357-UBR3:NM_172070:17
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.069 A=NA C2=0.021
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTCTGATGATGAGATTCTCAGGG
R:
TGGGAGTATACATGCCTTGTTGC
Band lengths:
222-1543
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)