HsaINT0178172 @ hg19
Intron Retention
Gene
ENSG00000183696 | UPP1
Description
uridine phosphorylase 1 [Source:HGNC Symbol;Acc:12576]
Coordinates
chr7:48134360-48139384:+
Coord C1 exon
chr7:48134360-48134424
Coord A exon
chr7:48134425-48139266
Coord C2 exon
chr7:48139267-48139384
Length
4842 bp
Sequences
Splice sites
5' ss Seq
CAAGTAAGG
5' ss Score
7.66
3' ss Seq
ACTTTCTTGTTTTTTAACAGTGA
3' ss Score
9.77
Exon sequences
Seq C1 exon
GGTCCTGCCTCAGTTGGCGGAATGGCGGCCACGGGAGCCAATGCAGAGAAAGCTGAAAGTCACAA
Seq A exon
GTAAGGCTCCATTTCATTCCAGGTTGGGTTGGGTGGGGTTGGGTTGTTTATAGAGCATATGTTGTGCCACACATTTTTCTAAGGACTTGACATATATTAACACATTTGATGCTTGTGAAAGAGACTGAGGCCTGGAGGGATTAATGACTCAGGAGGTTCGTACATTAGATGGTTAAAGACCTCCGGGGTCGGGTGCTGGGGCCTCAGCTCTTGATTCTTAGGACATGTTGTTTCAGAAAACCAGACAAGTCCCTGCTCAAATCTCTGTCTAGTAGGTTTTTCCTCTATGTGCCAATTTCTTAAACAAAATCCCCTGCTTATCACTCAGCTCTGCCTTGGTTCTGAATTTTAAATGCCTTCTTATTTCTTTGCAGTTTGTCATACTTCTGGTATGCTTGGCATGACACCACTTGTGTTTAGGCATTGCTAGAAAAGCAAGAATTTCTTGTCTTCATTCTGATTCCTATGTGAACTTTAATCCGCTGATTATTCTTATTTTCTCACCCCCCCAGTTGTCTCCCACCTCTGCTGGGGTTACCTGGGCAGGCCTTCTGTCCTGCCGCCATGGCCTCTCCCCAGTCTTGGTGGCCTCTGACCTTGGCACCACCCAGGGTTGTGGTGACCTCTGGCCCCCCTTGCTCTGGACTCCTGGTCCTTTGTTCCTCTGTAACTTCCCTGAGACCTCTCTGAAGTCTCACATGTGACAGCTGCATACCCAGGTCATAATTCCATATGGACAATGCTCTTCTCCTCCTCCATTCCCCAGAAGTCCTGGTGTCCATTTTGGAGTTTCTGGTGCCTGTGGACATTCCCTGCAGTGATTTTTTTTTTTTGAGATGGAGTTTTGCTCTTGTCGCCCAGGCTGGAGTGCAGTGAGTGGCGCAATCTCAGCTTGCTGCAACCTCTGCTTCCCAGTTTCAAGCAATTCTGGTGCCTCGGCCTCCCAGGTAGCTGGGATTACAGGTGCAAGCCAGCACACTTGGCTAATTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCCACCCGCCTCAGTCTCCCAAAGTGCTGGGATTACGGGCGTGAGCCACTGTGGCCTGCCTCAGTGATTATTTTTTAATTGAACTAATAGTATTCCTGGTATTTTCAGTCATTGACAGCCAAAAATGCCTTGTCCCCAGTTTCTGGAGCTCCCCTCCTTCCTCCTCCTGCCATGGCTTGAGGTTGAGGCCTAGTAGGAGGCTGGTGGGGGTGGAGGGGAGTGGTAGAAATGAAGGCTGGAGAAAACAGGGCCGGCACACCAAGTGCCAAGCAACTCAGTGAGGGTTTCCTCCCCTTCCCTCTCTTCAGTAATTATTTTACCCTCCCTTGTTTTATCCTCAGCTATCTGCTAATCATGTTCCACTTGCTGAAAGGCAGTCAGGTGTAGAGCTCAGGAGTACAGCCTCTTAGGAAGGATGTGACCTTGGACTTTGAATGGGGTTACTGATGGTACTTAGTTTATACTGAGAGTATTAAATGAATTGATATGTGCTAGCTATTAATAACTTCATTTCTACCCCAAGTCGAAAGCCTTCCATGAGTGGAACTGGATCTTACTCATCTTTATGTTCAGTACACCCAGCACAGGATGCTTGGCTGTTGCGAGATGCAGCCAGCATTTTCTGGAGCCCTCCCACTTCCCCTTCCCCAGTACCTCAGGCCCCTGTGTCTCACCCATCTCATTTTCTTCTTGTCTCCACATGTGCTGGTCCTAAGCTATTTGGGCAAGTTTATATAAAGGTTGATACTGCTTTCTCTTCCCTGCTGATAAACTCCTGGAATCAGAAGCCAGTTTTCATTGCTTTCTTTTTTTTCCTTTTTGTCTTTTATTGAGACAGGGTTTCGCCCTTTTACCTAGGCTGGAGTGCCGAGGTGTGATCTCAGCTCACTGCAACCTCTGCCTCCTGGGCTCAAGTGATCCTCTCACTTCAGCCTCCTGAGTAGCTGGGACTACAGGCATGCACCACCACACCCAGCTAATTTTTGTATTTTTCACAGAGACAGGGTTTCACTGTGTTGTCCAAGCTGATCTCAAACTCCTGGGCTCAAGTGATCTGCCCGCCTCAGCCTCCCAAATTGCTGGGATTACAGGCATGAGCCACCGCGCCCAGACAGTTTTCATTTCATTTCATATATTTCTTTTACATGGTAGATGCTCAATGAATATTTGCTAGATGAATAAAGTGGTAGAATAAAGCAGAATAAAGTCACTTGAAATTATGTGTAGACTAGAGAAATATTTTTTTCCAGGTAGTATGTCTCTGACTTGTTATTTTAAAATCCTTCAAAAAATAAATTGGGGCATCTACTGGTTCATTATGGTACATGTTAAATTTACTTTTTAAATTTTACTTTATTTTTTATTTTTAGACAGTCTTACTCTGTTACCTAGGCTGGAGTGCAGTGGTGTGATCAGGGCTCACTGCAGCCTCAACCTCCTGGGCTCAGGTGATCCTCCCACATCAGCCTCCCAGGGAGGTGGGACTATAGGTGCATGCCACCATGCCTGGCTAATTTTTACATTTTCTGTAGAGTCAGGGTTTCACCATGTTGCCCTGGCTAGTCTCGAATTCCTGGGCTCAAGTGATCCACCTGCGTTGGCCTCCTAAAGTACTGGGATTACAGGAGTGAGCCACTGTACCCGGCCAAATTTTCATGTTTTAAAATAATTGCCTGTCTTCACGGTTACACCCTACTTCCTTCTTCTTCATTTCTCAGAATCAAGGAGAAAAGACAAGTATTTTATTTTGAAATATGTGACAAAGTTGTCTTAATCACATCCTGTTTTGTTATTTTGAAGCATGACTCTTAGCCCTTCTATGTTGTACTCTGTGTATTTCTAACATCCTGAAGGAGGAGAATGGAAATGTTACTTACATGAAAAATAGTTGTCACTAAAGGATCCTAAAATACTGTGGGGTGTGCAGATCGTCAGAATTTCAGATTGGCCTAGAGATCAAAAAGGTTTTCTGAGAAAAGTTCAAGGATGGTCCTTACCACACGTGATTCTGGATTTGGTCGCTTGAAAAATGGCCTTGCCCCACATCCCAGAGTAGAATGAACCCTGATTCTGGAGATCCCCCCAATAGCTTGTCAGGAAGAGGTGGGCTTAGGGGCAGGCGGGTGTGGCTCTGTGCTTCAGGCAGGCTGCTGTGCCTTCCTGAGCAGGGTTTTCAGCAGATTCACTAGTGCAGTCAGCAGAGTCCCTGCCTGCCCATACAGGAGACAGTCACCTAGCCCCCTGTCCCCTTATACAAAGATCTCCCTGTCTCTGTGTATAACCCTTTGTACTTATGTTTTCTATATCAGCCTTTCTGAAATGTTCAGGTGTGAGCTCACCTGGGCCCCACTCTAGGGGAATTGATGGGAAGGAACATTTGACAGTCATGAAAGGAGGAAGCAGTCAGGTATAGGCCATCTGTGTGTTTGGAGCCTGGGTGTCTGCTGTTGATGAGTGCCAGATAGAAATAGGGATTTGATAAAATGATAGATAAAATAGGATGGGACCATCTCAACCTTGTTTTTCTTGTCTGTGGTGTGTTACGTGGGATTCAGAGATATATAAGACGTGGTCATGGCCTCCAGAAATTTTTGTTCTGGAGGTAAAGTTATTACATTAATTATGTATACCAGTGTTAAAATATAGATAAGGTGTAACAAGCATCGTGTGGGGAGAGAATGGACAATGTCTGTGAGGGGGGTGCATCCCTTATTTAACAGTTATTTCCAAATCCGTGGCAGCTGAGACCTTGCCTCTCTTGTGTCTTTTTCTTTTCTCATGAGTTAGAATGAGGAGGAGACATGACCACGGGGTTCAGGGCAGAAAGTCAGACTCAGAAGGAAGAAAAAGAAGTCCCCAATTGCTCTGACATCAGCATCCCATGTCTGCCTCTGTTTCCTGTAAGGGAGCCCACCCATCTCTAGGACTCAGAAGGCATACATTGTTGAAGGAGCTACGTTTGAGGCTGGCTCTAAGGGACTTCGACAGGCTTGAGGGACTCATCTAGACCTGGGGCATTTGTTTTGTAAGGAAGGTTTTATTGGAACACAGACACACTCACTCATTTGTGTGCTATCTGTAGTTGCTTTCACATGTCTACGGTGGACTTGAGAAGTAGCAGAAATCATGCAGCCTGCAAAACCACATGTATTTATTATCTGGCCTTTTATGAAGAAAAGTTTGCTGATGCTTGCTCTAGACCAGCATGTGCCACGAGCACATTTTCTAGCAGATAAACAGATGTCTTATCTTGTCACTCCTATTGGATATCGTGCTGGAGAAGTGGTAGCTAGTGTAACAAAAACAAAAACAAATTGAAGGTATGCAGATTGGAAAGGTTATCTCTGGGAGGTAGGATTAGAGGTTGTTTTTCCTTCTATTTCTGTTCATATTTCCTATGGTAAACATAGTAGTTTTAAAATAAATTCAAGTTTATACATCGAATGAACTTGATTAGAGGAGCAACTGGCTATACTCCCTACTCCTTGTATGGGTAGATCAAACATTTCCATCTGTGTACTTTCGTGTGCTCTTCTGATTTCATCCCTGTTGCCCTCCAAACAGAGCCATGGGAGCAACAGGGGTTAAGAGGGAGGAGAAGGGGGAAGAACAGAGGGGAGGCAAGTGCGGACCTTGGCAATGTTGGGGTTGTCTTATCTCCGGGATCTGGCCCTGTCTTTCTCCCACCATGAGCCTCGTGTCTGACATAGGCCACTTCTGTGATAATGTCGGCTGTCGGGCACTGATGTTCTATAAGCCTTCCACTTTCTTGTTTTTTAACAG
Seq C2 exon
TGATTGCCCCGTCAGACTTTTAAATCCAAACATAGCAAAAATGAAAGAAGATATTCTCTATCATTTCAATCTCACCACTAGCAGACACAATTTCCCAGCCTTGTTTGGAGATGTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000183696-UPP1:NM_181597:4
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.417 A=NA C2=0.011
Domain overlap (PFAM):
C1:
PF0104815=PNP_UDP_1=PU(1.2=22.2)
A:
NA
C2:
PF0104815=PNP_UDP_1=PU(0.1=0.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)