HsaINT0179974 @ hg38
Intron Retention
Gene
ENSG00000134215 | VAV3
Description
vav guanine nucleotide exchange factor 3 [Source:HGNC Symbol;Acc:HGNC:12659]
Coordinates
chr1:107772735-107777296:-
Coord C1 exon
chr1:107777231-107777296
Coord A exon
chr1:107772844-107777230
Coord C2 exon
chr1:107772735-107772843
Length
4387 bp
Sequences
Splice sites
5' ss Seq
AGAGTATGT
5' ss Score
5.66
3' ss Seq
TATGATATCCTTTGTTGTAGTGA
3' ss Score
6.21
Exon sequences
Seq C1 exon
GCCCTTCCCAACAGAAGAAAGCATTAATGATGAAGACATCTACAAAGGCCTTCCTGATTTAATAGA
Seq A exon
GTATGTTGAAAATTTCAAGCAAAATTTAGCCACTGCCAATTTATGTGTCCATTGTGGGTTTTAACTGTGGATGTTAAAGTAAGCTATCTGAAGGAGGAAAAGTGGCTTAATTACTGATTAACCTTAAACTGGCGATGGAAAGCTTTACAAGAAAATGTACTTCAACTGGTTTTTAGTTCCTGTTTTGTGTCCCCATGAAGAATAAAGAAACTTACTCTAATGAAGTAAAATTTCAAAGTTTCTCAAAGGCATAACAGAAGTAGTAGATAAAACTGGAGTTAGGGAACAATTTAAAAGAAATAGAATCTGCTGCTGGAGTTGTGGGACACATAGTGCATGCCTTATAAGTTCAAGGAAGGGAGAGATAAGTGTGGGTTGGAGCTATTCGGGATGTTTTAGTAGGCGGTGTTTGTTCTGAACAGAGAATCTTTTTGGGCTCTATTATTTAATAGTCAAGAGAGGCAAAAGGTCCTTGCAGCCGATTATCTTCTGCTGATTGAGTGACTTGTACAGATTACAAATAAATATATGCGTGATCGTTACTCCTCAAGGAACTGATGACATGGATCAGGCATGTTTGCAAAGAATCATAATAAGAAATAGATTATGCCCCAAGACAGATTCAAATGCTATGGAACTTCATCCATTCATTCATCTATCCTTCCTCATACACCCAACACACTGGGCTTGTTTTAGCCTTGTGACCTTTACACCTGCTATTCTTTCTGCCTGTTTGACTGATCCCTCAGCGTTCAAGTTTTTGCTTAGATTTCCCTACAGAGAGGCCTTCTCTGACTATCCTGTCTAAAATTGCCACCACCCCCTTACATTGCTGTGTTTTTACAGCATTTGCCAATGCCTGAGACAGTCTTGGTTTGCTTCATTTATTGTTTGTCTCCTCATTAGAAGGTACACTTTTGTGAGGTGTGGGACTTTGCCTTGTTCATGGCTGTATTCCTAGAACTTCACAGTGTCTGGCATATAGTAGGTACTCAATAAGTATTTGTTTTCCAAATTAATAAGTCAAAACTGCATCTAGCATCTACTGTTTGCCAGGTATTACACCTGGCAATAATAATAAGAGCTTACTGAGTTTCCATTTGTGTGCTAACCAGGTTATATGCACTATCTTATGTAATACCACAATATTACTAGGTTGTTATTATATCTTCACAGTTTAAAAGTGAGAAAACTGAATTTTGAAAAGCCTAGTTACTTGCTGAGGGTAATATTGCTAGTAAATTGTAGTCTTTGGATTTGAACTCAGACACCTCTTATTCTAGAGCAGAGGTTGTTAGTCACAGCCCCAACTTCCAGATCCCTCTCAGAGCTTTTAGTAGAAGAGTAGAGGGGGTGAGCACACCCACTGCAGTCACACGATGGATGGCCAGCAGCTCTTTCCAGGGTAGGTGGCCTTGAGAATGATCTTTCAGTCTTATATTTTAAATATCTATTAAGAGTAGTTTCTTATCTCTTAAAATCTCTAAGAACTCACCAACAGTAAGCAAGATAGTGCCAGTTGTTTTATTGAATTGGTTGTAATCTTCATAAAGTGACTAAGATTATTGGTAATGTACTCAGATTGTTTAAGGGGAATATTTAATTTCTAGTGCCGTGATGCTATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTGTGACTGAGTCTTGCTCTGGCACCCAGGCTAGAGTGCGATGGCACGATCTCAGCTCACTGCAACCTCCACCTCCTGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGCCTGCCACTGCGCCCAGTTAATTTTTTATTTTTAGTAGAGACAGGGTTTCACTGTGGTAGCCAGGATGGTCTCGAACTCCTGACCTCATGATCCACCTGCCTTGGTGTCCCAACGTGCTGGGACTACAGGTGTGAACCACTGTGCCCAGTCGATATTCTTTTTTAACCCATACCAGTGGTGACTTACACCTATAAATTTTTATAGCTTCCCCATTTTGTTCTTTTCACTGTTATTTAGGCAGACATGATGTCAGGATAAATCCAGTGAGGATGCATTCCTAGCTAAATTTGGAGAAAACCTTGGTTTCCTGAATTGGCTGCTCTGAGATGCCAGCCCTTGCTCTGTGAGAGGCAGTCTGCTTTAAATTTCTACCTGGTGGCCGAAGGTCCGAATGTATTTGCAGGATTAAAGAAATTATTTATTTAATATGCCCAGGCTGGTCTCCAACTCCTGGGCTCAAGCAATCCACCCACCTTGGCCTCCCAAAGTTCTGGGATAAAAGGTGAAGTAGGGTTATCTTAAAAAAAAAAAAAAAGCAAATGTATTATCCCTAGACATGCTTGGTTTTGAGTTTGCTGTGACAGCTTGATTTTTATTCTCAGCTTTATTACAATTTCTATGGGTAAATATACTTAACTCTAAATTTTGGGGCTGCATTCACCCAAACGGAAGCCCTTGGAATAAATACTGGCCTGGTCCCCACTGTGGAGGCAATCATTGTTTCCTAAGTTGGGGAGAAAGCCACAGGATGGAGTGGAGAGGGCAGGTAATGGCTACACTGTACAGTGTCCTTTTAGTATCAGGGCGCCAGACATGCCCGTATGTAGGTGGCCTTACATGTCGATTGTTTTTGATTTATTGACCATTTGAAAAATATCACAGCTTTTTTCTTTCCTGGCTCAGAAATCAGGAATTGTTGACTAAGCTGTTAGCAAGAAAAGCAGCTTTAGTAAAGGATTGAATAACAAAAGCCAAACAGTTCTAGACCAGTCTTGTGTGTGTGTTTGCGTTTGTGCACTTGCATGCACGCATGCACTCACACATGCATGTCATTCTTACAGGTCTTAAAATAGAGAAAAGTCAGCCAGGCGCGGTGGCTCATGCCTGTAATCCTAACATTTTGGGAGGCTGAGGTGGGCAGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAACTGGGCATGGTGGTGCGTGCCTGTAATTCCAGCTACCCAGGAGGCTGAGGCAGAAGAATCGCTGGAACCCAGGAGGTGGAGGCTGCAGTGAGCCAAGACTGCACCACCGTACTCCAGCCTGGGCAACAGAGTGAGACTCTGTCCCCCAAACAACAACAACAGCAAAAATAGAGAAAAGTCTGTGCTAATTTATATGATTCATTCCTTTACTGTCATGGGAAATAGTGAAATGTAGGACTTCAGCAAGGTTGACTTTTTTGCAGGGGTGGTGATGTTAGGGATGACAAGCAGGAGTTCTGGGATTAGGAGTGCCAGGGAAATGAATTTCAGTCCATTTTGCTTCCAAACAGGATCCCCTCCAATGCAGAACCTGTTTTTTCATCATTTTATATCTCAGCTCCTTCATGAACTCACCAGACCTTCCTATCCTTTGATGTGGTACAGAGAATGTGCAAACCGATTTACCTGCCCTAATGTTCTCTGGCCAGATTGCCGCCTAAACCCCTCAGTATGGAAATTATGTTACTGCCAATATGGATCACCATCTCCCTGGTGTCCCAAAGTAGAAAGCTCCTTCCTCTTCCTTCCTCCTCCCTCCCTTATTCTCAGTGTTCACCAAGTCTGGTTGTCCCAGTCTCCTATCTCTGTCTGTTCCTCTCCTCATCTGTCTTTATGTTAGTTATGGCCCTGAATATAAAACAGATAAAGGAAGGGTCTGGTTGATGGGGGACTGGTGGGTTTCCTCTGAATGGGCTTGAAAGAGCATGGGTTGAAAACCACTGGATTAGATGCTGATTATAACACTGCAGTAACTGATGCTTTTATAAGACCACTTATGACATATTAGATACAATTTAACTCTCCTATCTTCTCCATATTATACCCATTAATACAGTTGATGAAACTGAGGTCTTGAAATATGAAAAGTGGGAGGCAGTATGATAGAGTGGGTAAAACACTCAGCGTTAAGACAGACTTGGTTTTAAATATTGGATCTGCCAGTGACTACCTGGGTTATTTGTAAAGTCAAATAGCCTTTTGGTCTTTCAACTTCCTCATCTCTTTAATGGATTAAATAATAATGCACACCTGATCATTAATGTTGGATGAATTATGTAAGATAATATATGTAGAATAATTATTTTTGTGCTTATACATAGTAACTACCCAGTAAATGATGGCTGCCACTGCCCTCGTTATTGGATTCTGTAGTTGTCATTGTACCTATTAAGAGGGACAAAGTTGTAATGTAAACCTTTTGAACTCTTTCCACTAATTCCATTTTATTTCCTTTCTGGATTTTTTACTAAAATCCAGTAGGCTATTTGTAGCTATTGCATTTACTGCATAATAGAAAATGACCTTATATGATATCCTTTGTTGTAG
Seq C2 exon
TGAAACCCTTGTGGAAGATGAAGAAGATCTCTATGACTGTGTTTATGGGGAAGATGAAGGTGGAGAAGTCTATGAGGACTTAATGAAGGCAGAGGAAGCACATCAGCCC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000134215:ENST00000370056:4
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.106
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains