HsaINT0180188 @ hg19
Intron Retention
Gene
ENSG00000127831 | VIL1
Description
villin 1 [Source:HGNC Symbol;Acc:12690]
Coordinates
chr2:219303381-219305585:+
Coord C1 exon
chr2:219303381-219303449
Coord A exon
chr2:219303450-219305444
Coord C2 exon
chr2:219305445-219305585
Length
1995 bp
Sequences
Splice sites
5' ss Seq
GCTGTGAGT
5' ss Score
7.39
3' ss Seq
GGTTTCCTTTTCTTTCCTAGGAG
3' ss Score
9.77
Exon sequences
Seq C1 exon
AACACCAAATCCTATGAGGACCTGAAGGCGGAGCTTGGCAACTCTAGGGACTGGAGCCAGATCACTGCT
Seq A exon
GTGAGTCCGGGGCGGGGTGGCTGGGCCCTGCAGTGGCCAGCTGGTGGTCAGACCTGTGGGAGCCAAGAACGCTGCAGAGAAGACACCAGAGTCCTGTGCTTTCCCTCCTATTTCTCCCCCACTTCTCATTCTTCTTGCTGTTTTACTTCAGTGCCTCTAGTGGTTTTGTTTCCTCAATTTCCTAGTGAAATGGTTCTCAATTTTTTTTTTTTTTTTTTTTTTGAGACACAGTTTCACTCTGCCTCCCAGGCTGGAGTGCAGTGGCAGGATCTCAGCTCACTGCAACCTCCACCTCCTGGGTTCAAGTGATTCTCATGCCTCAACCTCCCAAGTAGCTGGGATTACAGGTGTGTGCCACCACGCCTGGCTAATTTTTGTATTTTTAGTAGAGACGAGGTTTCACCATGTTGGCCAGTCTGGTCTCAAACTCCTGACCTCAAGTGATCCACCAGCCTCGGCCTCCCAAAGTGCTAGGATTGCAGGCATGAGCCACCACACCTGGCCTGGTTCTCAAATTTTATCATGCATAGAAGTCGGGGAGATGGGGGCAGGGAGTGAGGGGGAAGCATATTAAAATGCAGATTCCAAGGCCCCATTCCCAAATATTCTGGTTTATAGACTTAGAATTGGCACCTAGGAATCTGCATCTTTTAAATCTTATTTTAAAAAGGTAATTTCATGTAGTTAGTCCATGGACTACACTTTGAGAAATAATGCTGTCTCTATACTCCATCACCTTTGGGATCCCTTCTCTAGGTAGAATAACTACAACTCCTTTGGTCTTTCAGTGAGTTAACAGAAGTGTATTTAGGCTGGGCACAGTGGCTCACGCCTGTAATCTCAGCACTTTGGGAGGCCGAGGTGGGTGGATTGCTTGAGCCCAGGAGTTTGAGACTAGTCTTCGTAACATGGGGAAACCCCATCTTTACAAAAAATAAAAAACAGCCAGGTGTGGTGGTGCGTGCTTGTGGTCCCAGCTACTCAGGAGGCTGAGGTGGGAGGTTGGTTTGAACCCAGGAGGCAGAGGTTGCAGTTAGCTGAAATTGTGCCACTGCACTCCAGCCTGGGCAACAGAGTCAGACCCTGTCTCAAAAAAAAAAAAAAAAAAAAACCCGAAAAAAGAAAAGAAAAAAAATGTATTTAGCCTTTAGGCCTGGGACACGGGAATATGAAATCAAAACCTTTGCTTTGAGAAGTTCACAGGCTTATAGAGAGAACAAGACAGAGCTAACTCTGAGGAATGTGTCCAGAATTCAAGAGCAAGTTCACAAGCACACTGGGGTATAATCAACAGATGGTCAAAACCTGCAGCACTCATGAAACCCTTCTTGGTGGACTGACAGTACAGACTGGCATGTATAGATAGGTCAAGGTTAAGTGAATTTATAGATGACAATTTCACAACAGATAAGAGAGACAGGGTCATAAATATCCAGGCTAGATCTCCAACTCTGGGGAAAGCCATGGGAAAGTTAATGAATCGTTAAAGAAAAGAGTCATTTTCCACCAATGGACTTCGGTCAGAACAGACCACTAAGCTCTATGTTGTTGTTGTTGTTGTTTTGAGGAGTCTCTCTCTGTTGCCCAGGCTGAAGTGCAGTGGCGCAATCTCAGCTCACTGCAACCTCCACCTCCCAGGTTCAAACGATTCTCCTACCTCAGCCTCCTGAGTAGATGGGATTACAGGCGCCTGACACCACACCTGGCTAAGTTTTGTATTTTTAGTAGAGATGCGGTTTCACCATGTTAGACAGGCTGGTCTTGAACTCCTGACCTCAAGTGATCCACCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGCACCCAGCCTATGTTGTTCTTATGAGTGTGTGTGTGGCAGGGTGGGGTGGGACATGGGAGGCTTCTTGAAGGTGGTGCCCTAGAGACTTCAGAGAGAAAGGCAGCCTGGGAGGTAGCTGTGCACCAGCTAAAGTAACCAGTGGTTTCCTTTTCTTTCCTAG
Seq C2 exon
GAGGTCACAAGCCCCAAAGTGGACGTGTTCAATGCTAACAGCAACCTCAGTTCTGGGCCTCTGCCCATCTTCCCCCTGGAGCAGCTAGTGAACAAGCCTGTAGAGGAGCTCCCCGAGGGTGTGGACCCCAGCAGGAAGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000127831-VIL1:NM_007127:18
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.043 A=NA C2=0.319
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCTATGAGGACCTGAAGGCG
R:
CTTCCTGCTGGGGTCCACA
Band lengths:
198-2193
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)