HsaINT0180819 @ hg19
Intron Retention
Gene
ENSG00000167987 | VPS37C
Description
vacuolar protein sorting 37 homolog C (S. cerevisiae) [Source:HGNC Symbol;Acc:26097]
Coordinates
chr11:60901508-60906307:-
Coord C1 exon
chr11:60906209-60906307
Coord A exon
chr11:60901680-60906208
Coord C2 exon
chr11:60901508-60901679
Length
4529 bp
Sequences
Splice sites
5' ss Seq
GAGGTAGAG
5' ss Score
4.86
3' ss Seq
CTGTTGTCCTGCCCTTTTAGGTC
3' ss Score
12.74
Exon sequences
Seq C1 exon
GGAAGGATGGAGACGCTGAAGGATAAGACCCTGCAGGAGCTGGAGGAGTTGCAGAATGACTCGGAGGCGATTGACCAGCTGGCCCTGGAGTCCCCTGAG
Seq A exon
GTAGAGGGAGGCTGGTATGGGACCCAACAGAGGCCAGCAGATGAGGCTTGTTAAGAGGCGCTTTTTAAGGATGCTGGCTTATTGGAAGTTTTGGCCAAATTCATCTCCCTTTTCTGTGAACTTCATCCTGGTTTGGACTCAGAGGAATCCCTGAGGCTTCAGACCAGTTCCTGGGAGTTCTTGGGAGTGCTGGGGAGTCCACTGCCTCCTGGTGCCTTCCCAGGACCCAGATACCCCAGGAGTCCCCACACTGTCGTTCCAGCCCAAATCTGGAGGCAGCTCCTCAAAGCACTGGTATGGTTTTGTACCCACTTTTCCCCAAGAGCCTTGTGCGATCCCATATCTCCAGGTGACTCTAAGGCTTCTAGGAGCCATTCTTGGGCTGAGATCTAGCTCGTCTCCCATTTGATCCTGTTTCTCCTCATAACTGGCCCCTAATCCTCTAGTTCTTAATCACAGACTCCTTGAGGAAAGAAACAGAATCCTGCCTGTGCAGAGATTTACACTTAATAAAGGACATTCCCTGCCCCTAGCATCTCCTGTGACCCTGGGATGTCCCCTGTGAGATGGGAGAGGTCAGGCCACACAGCCAGAAATATCCACGGTCACCCATTGAGTGGCTGCAGCTCATCCGTTGTGCTGGAAGCTCCCGCTTCCTATACCTAATGTGAGGGAGAGACACACACGCAAGCAATGCCAGCTCCTTTGATTTGCATTTGGAGTACATGTTTACTTGCACGGATGAGCAGGTATGGTGTGTCTCTTCTGTGAACTTGTATTTTGAAAAAAATAATGACGTTCCCCCATCCAGTGTCTCCGTGCTTCCATGCCATGGGGGGCGCCAGGCCGGTGAGTCCCCTGCTCCTGTTTCTGCTTGTGCTCTTGCTGCCTGCTGCCTGCTCTACTGCCTAAGTGAGGAATCTTAACTGGGGTTGGAGGTGACTGAACATTGGGTTGAAAAGATCTCCTGGTGGGGAGATTGTGAGGAGAGGTGGACACCATGGGCCACATCCTACCACCCTAGGGCTTTTTTAGTCCTCAGCAAGGACGTGGAGCAAAGCTTGCTTGTCGAAGCCCCAGGGCTGACTCAAATGGCTTGTGAGGCTGTGAGCTCTGCCAGGGCGTTGCTCCTGCCCAGCCTGGTGCTGGGCACAGTGCAGCTCTGCCTGCGTTCCTTTGTCACATATTAAGCACTGTGAGCATGGTGCCATGGGAAGCCCAAGGCCTGCTTCTAGAGTGTGCAGAGCTGAGCAGGCTGACAGAATCGTGACAAAGCAGAGAATCATGGAAAATGTGAGCAGAAGCGACCTCTTGGGCAGAAGGCACTTGAATTTTGTGGTGTGCAGCCACACCTGTCCCATCGATCTGAACTCTCTGAGGGGAAAAAACACTCGTGGATCAGGTAGAAATGAAGCAGGACAAGCCACTTAGACTTCAGACCATTGGCAAACTTTTTTATCGTGGGCTATAAGACAGTCATTGAGTCACAGTGGGATTGTGAGAAGAGACAGGAGCTCTCTATTAGTTCGGGACATGGACACGGCTAGGAGAGAAGGGAGTTGGCAGGGGCTCTCTCCGTGTAGAAGAGTGTGCATAGAGGGGTGTGTGGAGGGGAGCTGCTTTGGGTTGGGGGCCAGATATAGAAGGGAAACACCGTAACTTATTAAGGAAAGTTAGTCAAAATGGTTTTATCTCCCACTTTGCAACTTTTTTTAATTTTTGTTTTTTTAGGCAGGGTCTTACTTTGTCACCCAGGCTGGAGTGCAATGGCGCCATCATGGCTCACTGCAGCCTCCACCTCCTGAACTCAAACAATCCTCCCACCTCAGCCTCCCAAGTAGCTGGGACTACAGGTGCACACCACCACACCTGGCTAATTTCTAAATTTTACATAGCAACTTTTAAGAACTATTAGATACTTCTTGTTGAGTTTTGCTGTAGATTCAAAGAAAATTGATAATTATCTATAAAGGTTAGTAGCGACTCCTTCCTTTTCTAGCTATATATCTGTATGAGTATAGATTCTTCCTCCTTATTTCCACCAAAGTAATATACTAGGGCAGATTGAATTCAGAAGCAGCAAAACATGTGAAAACATCTTTTATTTACCTATTTTTAGTCTTACCTCTTTTCAGTGACTGGGAGGACTTCACACTGAACCCCTAATATGCATCGATATGCAATTTTCTAAATTGATGCATATTTTGCATATTTATGGGGAAGATGAGAATCTTTGTTGCATGCATAGAATGTGTGATGATCAGGCTGGGCGCGGTAGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGTGGAAGACCTGAGGTCAGGAGTTCGAGAGCAGCCTAGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGTGGCACGTGCCTGTAGTCCCAGCTACAAGGGAGCAAGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGCAGAGGTTGAAGTGAGCCGAGATTGCGCCATTGCACTCCAGCCTGGGCAACAGAGCGAAACTCTGTCTCAAAAAAAAAAAAAAAAAAAAAATGTGTAATTAAGGTCAGGGCATTTAGGGTCTCCATCACCTTGAGTATTTGTTGTTTCTGTGTGTTGGGAACATTTTACGCTTCTTGCTACTTTGAAATATACAATACATTGTTGCTGACCATAGTCACCCTACTCAGCTGTTGAACATTAGAACTTACTTCTTCTATCTACCTATATGTTTCTACCCATTGACCCACTTCGTGGAGAAAGATGTAAGAAGGCTGTGGAGACAGGGAGCAGAAATAAGTAGGGCAAGATTTAGGGGAAAATGATACAGCGTCGATTTGTTGGTTTAGACGCAGGGAAAAGGCAGTGGACCTATAGGGAGGCCAGAGGATCCATGGGGCCCTGCAAGGGATGGGTGAGCAGGAGGGCTTTAGGCCTTTCACTCTGGGTCAGCCATGTAAGTAAAGTTTCCATGGCTAATAAAAATTAGATTGAGAGTCACGTATGGTGGTTTGTGCCTGTAGTCCCAGCTATTGGAAGGATGGGATGGGAGGATTGTTTGAGGCCAGCCTGGGCAACGTAGGGAAACCCCATCTCTACAGAAAATAAAAGAACTTAGCCAGGCGTGGTGGTGCATGCCTGTAGTCCCAGCTGCTGGAAAGGCTGAGAAGGGAATATTGCTCGAGCTCAGGAGTTTGAGGCTGCAGTGACCTATGGTCATGCTATTGCACTCATTCTGGACGACAGAATGAGACCATGTCTGTAGAAGGCAGCAGCGTGGGCTCTAGGCTGGACAGACCCTGGGCCCTACATCCCTGAACCCTGGCAGCCTTGTCTGGAGGGCTCAGGGAGGGCAGGAAGCTGTGGTATCCCTCTTTCCAATCTGGAGCACAAAGAAGAGGCAATGGGCCTGCCCCAGAGTGCAGGACCTCGGCCCCTGTAGCTGGGACAGCAGAAGGGGTAGCCTTTCCCCGAGGCCGCCTCTTCCAGAATGCCCACGGGCTTCCTATGTCTCGTGGGGCATGAGCCAGTCTGGCTTGGTCTGTCACATGCTGACCATGGTGGAGAAGCTGCACAGAGAAGCTGCACAGTGAGGGCCTGACTTAGAGTCAGTCTTGCTGAGCTGTTCCCTGCGCCCTGTGGCGGGTGCCGAGGCCTCTCTTCTGGTGCCCCATGCTGCTGACAGTGTACTGTCACTGCTGGCTCAGCATGCAGGTCTGACTCCTCAGCCCTCCTCTTAGGAAGAGGACTCCTTGGCGGATGCATGGGGCGTCACATCACAACAGCTGGCAAGGGTGCCTTGGCTTCTGTCTCACTGGCTGGCAGCGACGAAGAGCCTGGCAGAGGGGTAAAGTGCCGCTTGGCTTGGGGAAGTGTTTGCAGCAGGGAATGTCCAGGGTGGCCCCTCTGGCTCATCTGTGCAGCTTCTCTGCAGGACACATGTGTGGCATAGGAGGCAGGTCCAGGTCTCTCCTAAGTCAGTGGCATGGTCTGGTCCAGGGACCTGGCTCTCTCACCCCTCACAATAACTTTATTTGGGGCCTCATTATATGTCTTGCCTGTGCATCTGGCCAGGACCACCTGAGCCCACCATGGTAGGTCTCTTGACTCTGAAGCTTGGGGATAAGTAATTGGGACTTTTGATCCCCTCCCTCCTGGAAAGCCTCTGCTTTTTCTCATGTAAATTGGTCCACCCCCTCCTTGGGGCTCTGCACATTCCATCATGGATATCAATCACATGGCCTTGGGCGAGCTCTTCACCTTCAGCGCCAGGTTCCCATGCGTCTCCACCTCGTGGGCTGTGGGTTAAGGATTAAGTGAGGCGCAGAGTACTTCATTCAGGGTTTGAACCTGGCTTTGTCTGACTAGTTGAGGGCTGAGTATTGCCCCAAGGATGAGCCTCTCCGCCCCAAGGTGAGCAATGTGTCCCCGAAGCCCCTGACCCAGGCTGCCAGGAGGTTAAGGGTGATGGACGTTTTCCTTAGGTTCTGTTGTCCTGCCCTTTTAG
Seq C2 exon
GTCCAGGACCTACAGCTGGAACGGGAGATGGCACTGGCCACCAACCGGAGCCTGGCAGAGCGGAACTTGGAGTTCCAGGGTCCCCTGGAGATCAGCCGCTCAAACCTCTCGGATAGATACCAGGAGCTCCGGAAGCTCGTGGAGCGGTGCCAGGAGCAGAAGGCAAAGCTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000167987-VPS37C:NM_017966:2
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.855 A=NA C2=0.121
Domain overlap (PFAM):
C1:
PF072008=Mod_r=PU(18.6=87.1),PF056227=HOOK=PU(31.2=96.8)
A:
NA
C2:
PF072008=Mod_r=FE(39.3=100),PF056227=HOOK=FE(59.4=100),PF0001021=HLH=PU(83.3=43.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)