HsaINT0182229 @ hg19
Intron Retention
Gene
ENSG00000196363 | WDR5
Description
WD repeat domain 5 [Source:HGNC Symbol;Acc:12757]
Coordinates
chr9:137020462-137020889:+
Coord C1 exon
chr9:137020462-137020495
Coord A exon
chr9:137020496-137020814
Coord C2 exon
chr9:137020815-137020889
Length
319 bp
Sequences
Splice sites
5' ss Seq
AAGGTGAGC
5' ss Score
9.6
3' ss Seq
CCTGTCCCCTCCTGTTTCAGTGC
3' ss Score
11.98
Exon sequences
Seq C1 exon
CACTCTGAAGCTCTGGGACTACAGCAAGGGGAAG
Seq A exon
GTGAGCCCCCGCAGGCTTGGGCCCCCATGGTGCACCATCCCTGGGTCATGGCCTCTGGTGGGGACAGAGCTGGCCCCGGTGATGACAAAGGAGAGGAGCTCAGAGAGCCATCTCCGCTGGGTTTGGTGCGAATTCCTGAAAGACCTGGGTATTTGTAGGGTGGCAGTCTGCAAGTTAAATCTTCGATTGTGTGGGTTTGGTACTTGTACTTTTCAGAAATAAGTGAAGTGAGTAGTGAAACGCCTTGCTTAGAACGTAGAATTACACAAAATCAAGGGGAACCATGACTCTGTGACCAGCCTGTCCCCTCCTGTTTCAG
Seq C2 exon
TGCCTGAAGACGTACACTGGCCACAAGAATGAGAAATACTGCATATTTGCCAATTTCTCTGTTACTGGTGGGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000196363-WDR5:NM_017588:11
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF085535=VID27=FE(9.9=100),PF0040027=WD40=PD(15.0=50.0),PF0040027=WD40=PU(2.4=8.3)
A:
NA
C2:
PF085535=VID27=PD(7.2=32.0),PF0040027=WD40=FE(57.1=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)