HsaINT0187234 @ hg19
Intron Retention
Gene
ENSG00000140987 | ZNF434
Description
zinc finger protein 434 [Source:HGNC Symbol;Acc:20812]
Coordinates
chr16:3432085-3434941:-
Coord C1 exon
chr16:3434459-3434941
Coord A exon
chr16:3433712-3434458
Coord C2 exon
chr16:3432085-3433711
Length
747 bp
Sequences
Splice sites
5' ss Seq
TTGGTAAGA
5' ss Score
8.85
3' ss Seq
GTGGGGTTTTTTTTTTTCAGGTT
3' ss Score
10.11
Exon sequences
Seq C1 exon
CAACAGGTGTGCCCTGGGGCTATGAAGAGACCAAGACGCTCCTGGCTATTCTTAGTAGTTCTCAATTTTATGGAAAACTCCAGACCTGTCAGCAGAACAGCCAGATCTACAGGGCCATGGCGGAAGGACTCTGGGAGCAGGGTTTTCTGCGGACCCCAGAACAGTGTCGCACCAAGTTCAAAAGCCTACAGTTGAGTTACCGCAAAGTGAGGAGAGGCCGTGTGCCTGAGCCTTGTATCTTTTATGAGGAAATGAATGCTCTTTCAGGCTCCTGGGCCTCTGCACCTCCTATGGCAAGCGATGCTGTTCCTGGCCAAGAAGGAAGTGATATTGAGGCTGGAGAGCTGAATCACCAGAATGGGGAACCCACGGAGGTAGAAGATGGCACTGTGGATGGTGCAGACAGGGATGAAAAGGACTTCAGGAATCCTGGCCAGGAAGTCAGGAAACTAGACCTGCCAGTGCTGTTCCCAAACAGACTTG
Seq A exon
GTAAGACTCCCTTGGCTCTGATGGTCAAAGGATGGCAAAGTCCACTTTAGAGGCCATTAGCCTAGCAGTTGAGTAGGAGCTGTCACTGATCCTGGCATCATCATCATCTTGATGTGTGACCCTATCCAAGTTTTGGTTTTCATGGAGTTAAAGGTTATTCCCCTTGCATTTTACAGCCCTGATTTTGCATTTGCCAACCTCTTTCAACTAAGTTCATGTCATCTTTTCCCATGGAGTTTCACTATGCATTGTCAGACTGCTGGTTAGGCCTCCAGACCAGGTCCATCTTCTCCCTTTTTCTCTAGCATGGCCTTGCCTTTCACAGCCTGAGCCTATGCTGGCTGGGTACTTAGCACCTTGCTTTCTTCCTGTTTGAGCTGGCCAAGCCCAGGGTTGCCTTTTGTTATTCTGCTGCTAGAAGTTAGAACATTCAAGAATTGAGGGTACACCTATAAACAGACTGGCAGATGATATAGTGCTTAATGTCTTGCCTCAGTTTGTCATTGTGTCAGAACATCCGAAAAAAGATAGGAGAAAAGTTGGAGTTTAGGGCATAATTTTCCTGTAATAATTTGGAGCTCAAAAATATTACAATGAGAAAATAAAAAGCTATTAATTAGCAGGAGACTTAATCACATGAAGAATTTCAATTAGATATTTCTTCTACGTAGTATAGTTATAACTTTGCATTCCATTGTTTTCCTTCTCTATAGTCCATTGTATTTCTGTGGGGTTTTTTTTTTTCAG
Seq C2 exon
GTTTTGAGTTCAAGAACGAGATTAAAAAAGAAAATCTAAAATGGGATGATTCAGAGGAAGTAGAAATAAACAAGGCTTTACAGAGAAAGTCCAGAGGAGTTTATTGGCACTCTGAGCTACAAAAAGGCTTGGAGAGTGAGCCAACATCAAGAAGGCAATGTAGAAATTCTCCAGGGGAGAGTGAGGAGAAAACCCCATCCCAGGAGAAGATGAGTCACCAGAGTTTTTGTGCCAGGGACAAAGCCTGTACACATATCCTCTGTGGGAAAAACTGCTCTCAGAGTGTGCACTCTCCCCACAAGCCAGCGCTCAAACTGGAAAAAGTATCTCAATGTCCTGAATGTGGGAAAACCTTTAGCCGAAGTTCTTATCTTGTTCGGCATCAAAGAATCCACACAGGCGAGAAGCCTCACAAGTGCAGTGAGTGCGGGAAGGGCTTTAGTGAGCGCTCCAACCTCACTGCCCACCTACGAACTCACACAGGGGAGAGGCCCTATCAGTGTGGGCAATGTGGGAAAAGCTTCAACCAGAGTTCCAGCCTCATTGTCCACCAGAGGACCCATACCGGGGAAAAGCCTTACCAGTGCATTGTCTGTGGAAAGAGATTCAACAACAGTTCCCAGTTCAGTGCTCACCGGCGCATCCACACTGGGGAGAGCCCATACAAGTGTGCAGTGTGTGGGAAAATCTTCAACAATAGCTCCCACTTCAGTGCCCACCGAAAAACCCACACTGGTGAAAAGCCTTACAGGTGTTCTCACTGTGAGAGAGGCTTCACTAAGAACTCTGCCCTCACCCGTCATCAGACAGTACACATGAAAGCAGTACTCTCATCACAGGAAGGAAGAGATGCGTTATGAGTGTGTCGGTAAACTGTCAGATTAAGTTCCTCAGGTCAGCATGTATGAGCTTTCTTCTGCTGTGGAGAGATCTAGCCAGTCCCTGACTTTGCAACAGACCTACTGACTACTGGATCTTAAGACCCATGTCTAGGACCAGGAGTCAGCATAAGGACGCTGACCTCTCCTGGCTGTGCCTGTGACTCCAGAGTCCTATCTTACTGTGACTTAAAGTTTGATGGAGAGAAAGCTGTAGGATCCATAAATTCTACCAGGAAACCAGGGTCTTCCTGTTCCTAGCACTGAGAATGGGCACCCAGTGGTCCAAGAACACTTTCTGGGCTAACATAGTCCTCACACAGGGCTGAGAAAGAAAGTGTCTCCTTTCCTGGAAAGCACATGTAAAAGTTAAGGGCCTGAATCTCTTCTAAACCAATAATTGACCTCTAGGCACCCACCGTAATACTGCTACCTTCAGGGCAGAAGACACTGCTCTTTGTAACCCAGCCACCACCAAAAAGCAAACAGAAAGAAGGAAGGATGGTTAAGCCATTGGATAATACTGAATCTGTTTCCCTAAGTGACTTAACCTTAGAGCAAGCACAACATCCAGGTTAATTTTTTGTAAGATTTCTCCTTTTATTATTGCCCTCATCATAGTTCCTGATTGTCTCTTAAAGTAAGTGGTTTATAGACATTACTATTTCTGATAATAATTTACAAACTACTATAAACAAATTTATAAACATTACTAATTTCTGATGAAAATAAAGTTGTTTCTCCCTCCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000140987-ZNF434:NM_017810:5
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.345 A=NA C2=0.280
Domain overlap (PFAM):
C1:
PF138371=Myb_DNA-bind_4=WD(100=53.1)
A:
NA
C2:
PF134651=zf-H2C2_2=WD(100=12.9),PF134651=zf-H2C2_2=WD(100=9.1),PF134651=zf-H2C2_2=WD(100=9.1),PF134651=zf-H2C2_2=WD(100=9.1),PF134651=zf-H2C2_2=WD(100=9.1),PF134651=zf-H2C2_2=WD(100=9.1)
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACCCACGGAGGTAGAAGATGG
R:
CCCTGGCACAAAAACTCTGGT
Band lengths:
356-1103
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)