HsaINT0187282 @ hg19
Intron Retention
Gene
ENSG00000185219 | ZNF445
Description
zinc finger protein 445 [Source:HGNC Symbol;Acc:21018]
Coordinates
chr3:44491005-44492065:-
Coord C1 exon
chr3:44491939-44492065
Coord A exon
chr3:44491116-44491938
Coord C2 exon
chr3:44491005-44491115
Length
823 bp
Sequences
Splice sites
5' ss Seq
TGGGTAAGT
5' ss Score
10.24
3' ss Seq
CATTCTCTTCTCTTCTGCAGTGG
3' ss Score
9.19
Exon sequences
Seq C1 exon
GAGACCATGACTTTCAAGGATGTGGAGGTGACCTTCTCCCAGGACGAGTGGGGGTGGCTGGACTCTGCTCAGAGGAACCTGTACAGGGATGTGATGCTGGAGAATTATAGGAACATGGCTTCCCTGG
Seq A exon
GTAAGTAATCGATATCCTCATGCTTCTATCCATCTTTATTTCTGCCTTCTTGGGTTGTTCTGTGCTGCATAGAAAGGTACCTGACCTGGTTTTAGATCCTGGCTCTGTAACTGCTGACCAGATCACTTAATCTAGCACCTTGGTAGCCTCTTTTGAAAAATGGGGAGAATAATGCCTGCCATTCTGGATTATTGTAAAGATTAAAGGTGGCTGGGTGTGGTAGCTCACACCTGTAATCCCACCACTTCGGGAGGCCCAGGTGGGAAGATTGCTTGAGCTCAGGAGTTTGAGACCAGTCTGGGCAACATAGTGAAACCCCATCTCTACAAAAAATACAAAAATACAAGCATGTGGTACGCACGCCTGTAATCCCAGCTACTTGGGAAGCCGAGGCTGGAGAATTGCTTGAGCCCAGGAGGATGAGGCTGCAGTGAGCCAAGATCGCACCACTGCACTCCAGCTTGGGTAACAGAGTGAGACCCTGTTTCAAAACAGACAAATAAAAACAACGGATTAAAGGTAATATGTTTTAAGTTCCTAGTCTGTTTAGACATTCAAAAAATGTTGGCTGATGTAACCAATTAAGTAGACGTGTGGTTCTCACCTCTGGAAAATTCTAGTAATCCTTTTGTGGGCAACTTCTATCAGTCTCTCTTATCTCTGCTCAGGGCTATTTGAAATGACTGGGCCTCCTTCGCTAGCTTCTGCTGCCTGCCTTCCTGGTCTTTCCCACCTTCCCACCAGGACTTCAGGCCCAGAGGTCCTGAAGAGTAGTTCTGTGTCATCCATCTCCCTTCTCATGCCATTCTCTTCTCTTCTGCAG
Seq C2 exon
TGGGACCATTCACCAAACCTGCTCTGATCTCCTGGTTGGAAGCAAGGGAGCCATGGGGCCTGAACATGCAGGCAGCTCAGCCTAAGGGGAATCCAGTTGCTGCTCCTACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000185219-ZNF445:NM_181489:6
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.045 A=NA C2=0.474
Domain overlap (PFAM):
C1:
PF0135222=KRAB=WD(100=95.3)
A:
NA
C2:
PF0135222=KRAB=PD(0.1=0.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGACCATGACTTTCAAGGATGTG
R:
CTGTAGGAGCAGCAACTGGAT
Band lengths:
238-1061
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)