HsaINT0187325 @ hg19
Intron Retention
Gene
ENSG00000197808 | ZNF461
Description
zinc finger protein 461 [Source:HGNC Symbol;Acc:21629]
Coordinates
chr19:37147350-37149327:-
Coord C1 exon
chr19:37149201-37149327
Coord A exon
chr19:37147446-37149200
Coord C2 exon
chr19:37147350-37147445
Length
1755 bp
Sequences
Splice sites
5' ss Seq
TTGGTAAAG
5' ss Score
4.05
3' ss Seq
ATTTCTTTTCTTATAACTAGGAC
3' ss Score
9.79
Exon sequences
Seq C1 exon
GAGTTGGTGATGTTCAGAGATGTGGCTATAGATGTCTCTCAGGAGGAATGGGAATGCCTGAACCCAGCGCAGAGGAATTTGTACAAGGAGGTGATGTTGGAGAATTATAGCAACTTGGTGTCACTTG
Seq A exon
GTAAAGTTATCTAAAAATTAAGAACCTGACAATTCAGAATTCCGCTAACAATTCACAATCTACTTCTTGGAATTTCTGCTTTCCCCCCTATTAATTTAGGGCTAGCTTTCAAATAACTGGATGAATTTTCTCTTTATGTATTGTAGAAACCAGCACAGCTAAATGGAGGTACATTTTCATTTTCCCCATCCTTACACGTTCTTTTGGTCCTTTCTTATAATAACTCCTCCTTGATGTTTAAGGGGCAGAATTGGAAATCTGCAATGTTAAAGCATAACACTGTCAAAGAAAGCAGACTCTGTCTTTTGTTTCACTTCCACTGTGCTAAATCTGCTAGTGTACTAGCATAAGATTAAAACTAGACACATGGGTTCCAGGAGTGAAGCTTTTTTCTTTCCTGGGTAATAGAGTGATAGGCTGGAGTAATAAAGGTTCATTTACTATTCTCAAATGAGCACCACTCCATTTCCTATAATAAATGTAATCTTTCACTTTTTATTTTATTTATTTATTTATTTTTGAGACGGAGTTTCGTTCTTATTGCCCAGGCTAGAGTGCAATGGCGTGATCTCGGCTCACCACAACCTCTGCCTCCCAGCTTCAAGCAATTCTCCTGCCTCAGCCTCCCGAGTAGCTGTGATTACAGGCATGTGCCAACACGCCTGGCTAGTTTTGTATTTTTAGTAGAGATGTGTTTTTTCCATGTTGGTCAGGCTGGTCTCAAACTCCCGACCTCAGGTGATCCACCTGCTTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCACCTGGCCTTTTTAATTTTTTTTTGAGACAGAGTTTCACTTTTGTTGCCCAGGCTAGAGTGCAATGGCATATCTTGGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGTGCCCGCCACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAATTCCTGATCTCAAGTGATCCACCCGTCTTGGCCTCCCAAAATGCTGGGATTACAGGTGTGAGCCACCGCGCCTGACCTGTACTCTCTTTTAAGTGATTTGCCTTTGGAAGTTATTTTTAAAGAACTTTGTACAGTTAACATTAAAAAAAAAAAGGAGGCTGGGTGCTGTGGCTCATGCCTGTAATCCCAGCACTTTGGGACGCTGAGGCAAGTGGATCACCTGAGGCCAGGAGTTTGAGACCAGCCTGGCCAATATGGGCCAAACCCCGTTTCTACTAAAATACAAAAATTAGCCAGGCAGAGTGGTGTGCGCCTATAATCCCAGCTACTTAGGAGGCTGAGGCAGGAGAGTCACTTGAACCCGTGAAGTGGAGGTTGCAGTCAGCCAAGATTGTGCCATTGCACTCCAGCCTGGACAACAAGAGCAAAACTCCATCTCAAAAAAAAAAAAAAGAATAAATATCTCAAGAAGCTTCTTTTTTTTCCTCACAGCAAAAAAGAGAAACCTTACATAAATTTAAGTACTATTTTATCGCCTGTTTGTTTGCTTTGTTTGTTATGATCCTGTGTTCATCTGAATATGAGTGTTTCATCTCTTCTCCTTTATTTCCTCTGTATCCCTTATCAAGTACCATTTTTATCTGTGATTTATTTTTATTTTAATCAGTTCTAAATCACTGTATTTGGATACATTCATTTCCATCTCATCTCAATTTCTTTTCTTATAACTAG
Seq C2 exon
GACTTTCTGTTTCTAAGCCAGCCGTAATCTCCTCATTGGAGCAAGGGAAGGAGCCCTGGATGGTTGTGAGGGAAGAGACAGGAAGATGGTGCCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197808-ZNF461:NM_153257:3
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0135222=KRAB=WD(100=100.0)
A:
NA
C2:
PF0135222=KRAB=PD(6.5=22.2)
Main Inclusion Isoform:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGTGATGTTCAGAGATGTGGC
R:
GGCACCATCTTCCTGTCTCTT
Band lengths:
216-1971
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)