HsaINT0187995 @ hg19
Intron Retention
Gene
ENSG00000167395 | ZNF646
Description
zinc finger protein 646 [Source:HGNC Symbol;Acc:29004]
Coordinates
chr16:31087567-31094833:+
Coord C1 exon
chr16:31087567-31093022
Coord A exon
chr16:31093023-31094291
Coord C2 exon
chr16:31094292-31094833
Length
1269 bp
Sequences
Splice sites
5' ss Seq
CCGGTAGGG
5' ss Score
7.63
3' ss Seq
TCCTCTCTCTCTCCCCCCAGGAG
3' ss Score
14.18
Exon sequences
Seq C1 exon
GCCTTGGCCCCTCCACCAGAGGAAGGTGCTGCCACGTGTCTGCTCCTTCTGAACCTCCAGGTTTCTGCTACGTTGCCCCATGGAGGACACACCCCCCTCACTCAGCTGCTCCGACTGTCAGCGCCACTTTCCCAGCCTCCCAGAGCTCTCTCGGCACCGAGAACTGCTCCATCCATCTCCCAACCAGGACAGTGAGGAGGCTGACAGCATCCCTCGGCCCTACCGTTGTCAGCAGTGTGGGCGGGGCTACCGTCACCCCGGGAGCCTGGTTAACCATCGTCGGACCCACGAGACTGGCCTTTTCCCCTGTACCACCTGTGGCAAGGACTTCTCCAATCCCATGGCTCTCAAGAGCCATATGAGGACACATGCTCCTGAGGGCCGCCGCAGGCACAGGCCCCCACGCCCCAAGGAAGCCACTCCACACCTCCAGGGTGAGACGGTGTCCACTGACTCCTGGGGCCAAAGGCTTGGCTCTAGTGAAGGCTGGGAAAACCAGACAAAACATACAGAAGAGACACCTGACTGTGAATCTGTACCTGACCCCAGGGCAGCTTCGGGTACGTGGGAAGATCTGCCCACCAGACAAAGAGAAGGCTTGGCAAGCCACCCAGGTCCTGAGGATGGTGCAGACGGCTGGGGACCCTCCACTAACTCTGCCAGAGCCCCTCCTCTCCCCATCCCAGCCAGCAGCCTTCTTAGCAACTTGGAACAGTATCTGGCTGAATCAGTAGTGAACTTCACAGGGGGCCAGGAGCCCACCCAGTCCCCTCCTGCTGAGGAGGAGCGGCGGTACAAATGTAGTCAGTGTGGCAAGACCTACAAGCACGCCGGGAGCCTCACCAACCACCGCCAGAGCCACACGCTGGGCATCTACCCCTGTGCCATCTGTTTCAAGGAGTTCTCTAACCTCATGGCTCTGAAGAACCACTCTCGACTGCATGCCCAGTATCGGCCTTACCACTGTCCCCACTGCCCCCGTGTCTTCCGGCTCCCCCGGGAGCTGCTGGAACACCAGCAGTCCCATGAGGGTGAAAGGCAGGAGCCACGCTGGGAGGAGAAAGGGATGCCCACCACCAATGGGCACACAGATGAGAGCAGCCAGGACCAGCTCCCCAGTGCACAGATGCTGAATGGCTCTGCGGAGCTCAGCACCTCTGGGGAGCTGGAGGACAGTGGCCTGGAGGAATACCGGCCTTTCCGCTGTGGGGACTGTGGCCGTACTTACCGCCATGCTGGGAGCCTCATCAACCATCGAAAGAGCCACCAGACAGGTGTCTACCCCTGCTCACTCTGTTCTAAGCAGCTGTTCAATGCGGCTGCCCTCAAAAACCATGTGCGGGCTCATCACAGGCCCAGGCAAGGAGTTGGGGAAAATGGGCAGCCATCAGTCCCACCAGCTCCCCTGCTGCTGGCTGAGACCACCCACAAAGAGGAAGAGGACCCCACCACCACCCTGGACCATCGGCCCTATAAGTGCAGTGAGTGTGGTCGTGCTTACCGCCACCGGGGGAGCCTGGTGAACCATCGCCACAGCCATCGGACTGGAGAGTACCAGTGCTCACTCTGTCCCCGCAAGTACCCCAATCTCATGGCCCTGCGCAACCACGTGCGGGTACATTGCAAGGCTGCTCGCCGAAGTGCAGACATCGGGGCTGAGGGTGCCCCCAGCCACCTCAAGGTAGAACTCCCGCCTGACCCAGTGGAGGCAGAGGCAGCCCCGCACACAGATCAGGACCATGTGTGCAAACATGAAGAAGAGGCCACGGACATCACCCCAGCAGCAGACAAGACAGCAGCACATATCTGTAGCATCTGTGGGCTGCTCTTTGAAGACGCTGAGAGCCTTGAACGTCATGGCCTGACTCATGGGGCAGGGGAAAAGGAAAATAGCAGAACAGAGACCACAATGTCACCTCCTAGGGCCTTTGCCTGCCGAGACTGTGGAAAGAGCTATCGCCACTCAGGCAGCCTTATCAACCACAGGCAGACCCACCAGACAGGAGACTTCAGTTGTGGGGCCTGTGCCAAGCACTTCCACACCATGGCTGCCATGAAGAACCACTTGCGCCGGCACAGTCGGCGGCGGAGCAGGCGGCATCGGAAGCGGGCTGGCGGTGCCAGCGGTGGGAGAGAAGCCAAACTCCTGGCAGCGGAGAGCTGGACCCGGGAGCTAGAAGACAATGAAGGCCTGGAGTCTCCCCAAGACCCTTCAGGGGAAAGTCCTCATGGGGCTGAAGGCAACCTGGAAAGTGATGGGGACTGTTTGCAGGCTGAATCTGAAGGGGACAAATGTGGGCTTGAGAGGGATGAGACCCATTTCCAGGGTGATAAAGAGAGCGGAGGCACTGGGGAAGGACTGGAAAGGAAGGATGCCAGTTTACTTGACAACTTGGACATCCCAGGTGAGGAAGGTGGTGGCACTCACTTCTGCGATAGCCTCACTGGGGTGGATGAAGACCAGAAGCCAGCCACTGGCCAACCCAACTCCTCTTCCCACTCTGCCAATGCTGTCACTGGCTGGCAGGCTGGGGCCGCTCACACATGCTCTGACTGTGGGCATTCTTTCCCCCATGCCACTGGCCTGCTGAGCCACAGGCCCTGCCACCCACCAGGCATCTATCAGTGCTCCCTCTGCCCGAAGGAGTTTGACTCTCTGCCTGCCCTCCGCAGCCACTTCCAGAACCATAGGCCTGGGGAGGCGACCTCAGCACAGCCTTTCCTCTGCTGCCTCTGTGGCATGATCTTCCCTGGGCGGGCTGGCTACAGGCTTCACCGGCGCCAGGCCCACAGCTCCTCTGGCATGACTGAGGGCTCAGAGGAGGAGGGGGAAGAGGAAGGAGTGGCAGAGGCAGCCCCTGCACGCAGTCCACCACTGCAGCTCTCGGAAGCAGAGCTGCTGAATCAGCTGCAGCGGGAGGTGGAAGCGCTGGACAGTGCAGGGTATGGGCACATCTGTGGCTGCTGTGGTCAGACCTACGATGACCTGGGGAGCCTGGAGCGTCACCACCAAAGTCAGAGTTCTGGGACTACTGCAGACAAGGCTCCCAGCCCCTTGGGAGTGGCAGGTGATGCCATGGAGATGGTCGTGGACAGTGTCTTGGAGGACATAGTGAATTCTGTCTCTGGAGAGGGTGGAGATGCCAAGTCTCAAGAGGGAGCAGGCACCCCCTTGGGAGACAGCCTCTGCATCCAGGGTGGGGAAAGTTTGTTGGAGGCTCAGCCCCGCCCCTTCCGCTGCAACCAGTGTGGCAAGACCTATCGCCATGGGGGCAGCCTGGTGAACCACCGCAAGATCCACCAGACTGGAGACTTTCTCTGCCCTGTCTGCTCCCGCTGCTACCCCAACCTGGCTGCCTACCGTAATCATCTGCGGAACCACCCTCGCTGCAAAGGCTCTGAGCCCCAGGTTGGGCCCATCCCAGAGGCAGCAGGTAGCAGTGAGCTGCAGGTTGGGCCCATCCCAGAAGGAGGCAGCAACAAGCCCCAGCACATGGCAGAGGAGGGGCCGGGGCAAGCAGAAGTCGAGAAGCTCCAGGAAGAACTTAAAGTGGAGCCCCTGGAGGAAGTGGCCAGGGTGAAAGAAGAGGTGTGGGAGGAGACCACTGTGAAGGGGGAGGAGATAGAGCCCAGGCTGGAGACTGCCGAGAAGGGCTGCCAGACTGAAGCCAGCTCTGAGCGGCCCTTCAGCTGCGAGGTGTGTGGCCGATCCTACAAGCACGCCGGCAGCCTCATCAACCACCGGCAGAGCCACCAGACCGGCCACTTTGGCTGTCAGGCCTGCTCCAAGGGCTTCTCAAACCTCATGTCCCTCAAGAACCACCGGCGCATCCATGCAGATCCCCGACGTTTCCGCTGCAGCGAGTGTGGGAAGGCCTTCCGCCTGCGGAAACAGCTGGCCAGCCACCAGCGGGTCCACATGGAACGGCGTGGGGGTGGGGGCACCCGAAAGGCGACTCGGGAAGATCGGCCCTTCCGCTGTGGGCAGTGCGGGCGGACCTATCGCCACGCCGGCAGCCTCCTGAACCACCGGCGCAGCCACGAGACGGGCCAGTACAGCTGCCCCACCTGCCCCAAGACCTACTCCAACCGCATGGCCCTGAAGGACCACCAGAGGCTGCACTCAGAGAATCGGCGGCGACGGGCTGGACGGTCCAGGCGCACAGCTGTGCGTTGCGCCCTCTGTGGCCGCAGCTTCCCTGGCCGGGGATCTTTGGAGCGGCACCTGCGGGAGCATGAGGAGACAGAAAGGGAGCCAGCCAATGGCCAGGGAGGCCTGGATGGCACAGCGGCCAGTGAGGCGAACCTGACTGGCAGCCAGGGACTAGAGACCCAATTGGGTGGTGCTGAGCCAGTACCCCACTTGGAGGATGGAGTCCCAAGGCCAGGGGAGCGCAGTCAGAGCCCCATCAGGGCAGCAAGCTCAGAAGCCCCAGAGCCACTGTCCTGGGGTGCAGGGAAGGCAGGTGGGTGGCCGGTAGGTGGGGGACTGGGGAATCATAGTGGAGGCTGGGTTCCTCAGTTCCTAACTAGGTCAGAGGAGCCAGAGGACAGTGTCCACAGGAGTCCTTGCCACGCTGGTGACTGCCAGCTCAATGGACCTACTCTGAGTCACATGGATAGCTGGGACAACAGAGACAACAGCTCTCAGCTGCAGCCAGGGAGCCACTCCTCTTGCAGCCAGTGTGGCAAGACTTACTGCCAGTCAGGCAGCCTCTTGAACCACAACACCAACAAGACAGACCGACACTATTGCCTGCTCTGCTCCAAGGAGTTCTTAAATCCTGTGGCCACAAAGAGCCACAGCCACAACCACATAGACGCCCAGACCTTTGCCTGTCCTGACTGTGGCAAAGCCTTTGAGTCCCACCAGGAACTGGCCAGCCACCTGCAGGCTCATGCCCGGGGCCACAGCCAGGTGCCAGCCCAGATGGAGGAGGCCAGAGATCCCAAAGCCGGGACTGGGGAGGACCAGGTGGTTCTCCCTGGTCAAGGGAAAGCCCAGGAGGCCCCATCAGAAACCCCCAGAGGCCCAGGAGAGAGTGTGGAGAGAGCCAGGGGAGGACAAGCGGTGACGTCCATGGCGGCTGAGGACAAGGAGCGGCCCTTCCGCTGCACCCAGTGCGGGCGCTCCTACCGCCATGCTGGCAGCCTGCTGAACCACCAGAAGGCCCACACCACAGGGTTGTACCCGTGCTCCCTCTGTCCCAAACTTCTCCCTAACCTGCTGTCTCTTAAGAACCACAGCAGGACCCACACGGACCCCAAGCGCCACTGCTGCAGCATCTGTGGCAAGGCCTTTCGGACAGCTGCCCGGCTGGAGGGCCACGGGCGGGTCCATGCACCCCGGGAGGGGCCTTTCACCTGCCCCCATTGTCCCCGCCACTTCCGCCGCCGAATCAGCTTCGTGCAGCACCAGCAGCAGCACCAGGAGGAGTGGACGGTGGCCGGCTCCG
Seq A exon
GTAGGGGGCATGAAGGGTCCCAGGAGGAGGTGGGCACACAGTGGAGGGGGAAGTCCAGCCCCAAAGTCGGTGGGGGAGCAAGGAGTGAGAGGAGAGAGCCCCGGGGATTCTAAGAGGTGGGTGGGGGCTTGGCTATGGGGTGAGAGAAGTAGCTTGAGGATGTGCTGAGCTGAGCACCCGCAAGTCAGGTATAACAAATAGCAGGGTGGGTTGGGCAGCACGTGGGGGCGTGGTCAGGCCGAGGCTGCTACCTGGGCTCCTCCATTACACTGTAGCCAGAATGGAATGGTCTTTCTGTTCAGGGGAAGGTCACTGGGTACCCCCTGGCTGCTGTGTCTGGAAACCCTCCTGAGTCAGCCAGTAAAGTAATGACTTCCAGAGAAAAAGAGGAAGCCATTGGTTTGGTCTAGGTTCCATTCTTTCCTGGAGCAGGCCGGGTGCCAGGGAACAAGGGATGGGGCATGGGCTCCACGGCTTCCCTGCTGACTTGGCCACGGAAACTGGTTCACTGGTTGGCACCCTACTCCCTGTCCCTCTTTCCCTGCGCCTTGTCTCTGCTGCTCCTCTCCTTGGAAACTAGACCTCTGGTCCTTCCCTGTCAGTGTTGCTCCCATCTCTTCTCTAACCTTTATTCAGCCCCTTTTCCCTCTGCTGCCAACGGCCTTTTTAGGATCCAACCAAACCACCCTTTCTACCTGCGCACCCTGCCACCCTCTGCACACCTTTAACTGGAGGACTGAGTCACAGATAATTGTTTCCTTGAAGTCCAGGCCCAGCTGCAGCAACAACAGTCATTAGCCCGTGTCACATCCCTGATCAGAGGGCATCTCCGTGGGGAATCGCCTCCACCCAGCACTGCTGGAAGCCGCAGCTGCCAGGGAGTGGGGCGGCCGGTTCCCTCAGCAGGACCTGGGCTGGCCTCTCCACCTCCCCTAGTAGAGGCGGACCCATTCCATCTAGTGGCCACCGAGGGTGGGTGGCCCTGAGATGGTGGGCCCTTGACAGGCCTTGTCAGAGCAGAGGGCAGGTGGGAGTCACCTGAAAGCTGAAGGAATGGCTTTAAGGATAGAAGATTTCTCATGACCTCAAGGGATATGAGGGAGGAGCCAGTTTGCCAGGGCTGGGAAAATAATTAGGAGGCCTAGAATCCCTGTTCTCATCTGGGCCTCCGGGGCCAGGGGCAGGGGAATGGCCTGCAGGGCTGGGAGGGGGTACACGCTGTGCGGGGTCTGCCCCTCAGTTGGTGACCTCCTCTCTCTCTCCCCCCAG
Seq C2 exon
GAGCCCCAGTGGCACCAGTGACGGGCAGAGGGGACTTGCCATTGCCCCCTCCACCCACCCCCACGACCCCACTCCTGGATCCTTCACCCCAGTGGCCTGCAGACCTCAGCTTCTCCCTCTGAACTTCAAGTCTCCAAAGATCAGAATCTGGGGGAGGGAGCGCGTGCAGGGAGGGGCTTGATCTCCACATTTTCTCAGGAGTAGTTCGGGCATCCCCATATCTTCTCCTCTCCCCTTGTGAAGAGGACCCAGATCTGGCTTCTTTCCCAAGGAGGGGGTGGGGTGTTCCTCGCGTCCCTGTCCTTGAAGGACCTCCTTCCCCCAGCCTCATCACCGTGCTCTTCTCAGCGCCACCCTCAGCAGCCAGATTGCAACACCAGGGAGAGGCGGATGCAGAGCCCCACCGGTGGGAAAGTTGCCTGTGGAAGGGAGCCTTTTGCTACAATTTGTAACTTATTTTCTAAAGTCTATTTTGTAACAATTTATTTAAGTTTAAAAAAAGGAAAACTGCTGCCCCCCAAAAAAAGAAATTTTCAAAACAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000167395-ZNF646:NM_014699:2
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.613 A=NA C2=0.750
Domain overlap (PFAM):
C1:
PF0009621=zf-C2H2=WD(100=1.3),PF0009621=zf-C2H2=WD(100=1.3),PF0009621=zf-C2H2=WD(100=1.3),PF0009621=zf-C2H2=WD(100=1.3),PF0009621=zf-C2H2=WD(100=1.3),PF0009621=zf-C2H2=WD(100=1.3),PF138941=zf-C2H2_4=WD(100=1.3),PF0009621=zf-C2H2=WD(100=1.3),PF138941=zf-C2H2_4=WD(100=1.3),PF0009621=zf-C2H2=WD(100=1.3),PF121713=zf-C2H2_jaz=WD(100=1.2),PF138941=zf-C2H2_4=WD(100=1.3),PF0009621=zf-C2H2=WD(100=1.3),PF0009621=zf-C2H2=WD(100=1.3),PF0172213=BolA=WD(100=3.2),PF0009621=zf-C2H2=WD(100=1.3),PF0009621=zf-C2H2=WD(100=1.3),PF0009621=zf-C2H2=WD(100=1.3),PF0009621=zf-C2H2=WD(100=1.3),PF0009621=zf-C2H2=WD(100=1.3),PF0009621=zf-C2H2=WD(100=1.3),PF0009621=zf-C2H2=WD(100=1.3),PF134651=zf-H2C2_2=WD(100=1.5),PF0009621=zf-C2H2=WD(100=1.3)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TAAGAACCACAGCAGGACCCA
R:
CAGAGGGAGAAGCTGAGGTCT
Band lengths:
342-1611
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)