HsaINT0188266 @ hg38
Intron Retention
Gene
ENSG00000185252 | ZNF74
Description
zinc finger protein 74 [Source:HGNC Symbol;Acc:HGNC:13144]
Coordinates
chr22:20400632-20401372:+
Coord C1 exon
chr22:20400632-20400758
Coord A exon
chr22:20400759-20401276
Coord C2 exon
chr22:20401277-20401372
Length
518 bp
Sequences
Splice sites
5' ss Seq
TAGGTAAAA
5' ss Score
6.02
3' ss Seq
CACTTTCTCTCCACGAGCAGGAC
3' ss Score
6.12
Exon sequences
Seq C1 exon
GAATCGGTGAGTTTCAAGGATGTGGCTGTGGACTTCACCCAGGAGGAGTGGGGTCAACTAGACTCCCCTCAGAGGGCCTTGTACCGGGATGTGATGTTGGAGAACTACCAGAACCTTCTTGCCCTAG
Seq A exon
GTAAAATCCCCCCAGCCCCAGGCTGGGCGTCGGCTGTCAGCCTTCTTCTACATGGTAGATATTAAGGAGAATCCCTTCAGTGCCGGCCCTGGTGCCAGATATATCATGGGGTGGGAAGCAAGGCCTGTGCCTTGGGGCACTCATGGCCAGGGGCCTCGGCCACGCCAGAAGTCCCCAAGGGACAGCGTGGGAGCTGGTAGCATCCTTGCTTGGTGTTTCCCCTGGTCCTGGGATAGGGGCAGGGAGAGAAGAGAAGAAGGTGGGACCCTGGAGCCCAGCTGGCTCTGGAACAGTCCTCAAGCAATGAAGTAAGGACGTCAGCACACGTGGGGTCTTCAGAGTATACACTGGGATTTGGGTTCCAGTCTGAGACCCTCACTGCTTTTGGCCCAGAGGACCTCCTGTTCCCAGAGAGGGTGTCCACTTCACAGGCATTGTCCTTGTTAGGGGGCGGCCTGTAAGGTCGACTGGGCCTGGAGAGCTGCAGCATGCCCAGCCCACTTTCTCTCCACGAGCAG
Seq C2 exon
GACCTCCACTGCACAAGCCAGATGTGATCTCTCATCTGGAACGAGGCGAGGAGCCATGGAGCATGCAGAGGGAAGTCCCCAGAGGGCCCTGTCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000185252:ENST00000357502:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.344 A=NA C2=0.856
Domain overlap (PFAM):
C1:
PF0135222=KRAB=WD(100=95.3)
A:
NA
C2:
PF0135222=KRAB=PD(0.1=0.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AATCGGTGAGTTTCAAGGATGTGG
R:
CTGGACAGGGCCCTCTGG
Band lengths:
222-740
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains