HsaINT1005391 @ hg38
Intron Retention
Gene
ENSG00000204256 | BRD2
Description
bromodomain containing 2 [Source:HGNC Symbol;Acc:HGNC:1103]
Coordinates
chr6:32976562-32977570:+
Coord C1 exon
chr6:32976562-32976936
Coord A exon
chr6:32976937-32977441
Coord C2 exon
chr6:32977442-32977570
Length
505 bp
Sequences
Splice sites
5' ss Seq
AAGGTACCC
5' ss Score
9.16
3' ss Seq
GATGCTGCCTCCTTCTGCAGCGG
3' ss Score
9.38
Exon sequences
Seq C1 exon
AAAAAAGGCGTAAAGCGGAAAGCAGATACTACCACCCCTACACCTACAGCCATCTTGGCTCCTGGTTCTCCAGCTAGCCCTCCTGGGAGTCTTGAGCCTAAGGCAGCACGGCTTCCCCCTATGCGTAGAGAGAGTGGTCGCCCCATCAAGCCCCCACGCAAAGACTTGCCTGACTCTCAGCAACAACACCAGAGCTCTAAGAAAGGAAAGCTTTCAGAACAGTTAAAACATTGCAATGGCATTTTGAAGGAGTTACTCTCTAAGAAGCATGCTGCCTATGCTTGGCCTTTCTATAAACCAGTGGATGCTTCTGCACTTGGCCTGCATGACTACCATGACATCATTAAGCACCCCATGGACCTCAGCACTGTCAAG
Seq A exon
GTACCCACTGCATGGGGCAGATGGGATGCTCAGGCAGTGATGGGAGCCTAGGTGCAAAACAATAAGTCTCCTTATGTGGGCACACAGCAGTCTTTGGTTCTTGGCATTTTACTTTTATAAAATAATAGTGGAACAGAAGGTCTGGTGTTTTGAGAATTTGTATTTCTTGGAGTTTGAAACAGTAGGGTGGGGTTTCTTTGTCTTGAGAAAAATACTGTCTATAATTAAGTACTAATGTGGCAGTGTTGGGTTAAGGAAGTTATAGGGTGGAAAAACAGGCATAGGCCACCTCTCTGTCACTTAGAAATGATTTCTTTTTCTAGACATAAATATTTCTTCAACCCACCCAAATTCCTTTGACTTCAAACTTGAACCCCAGGGCACAGATCCTTAAGGTCATCCCCACTGTGCTCTCAAGAGAGGGCTCTTCTTGTGGTGTCTGGGGTTGGCAGGGAAAGGTGAGTCTTCCTGCCTGTGCAGCTTCTGATGCTGCCTCCTTCTGCAG
Seq C2 exon
CGGAAGATGGAGAACCGTGATTACCGGGATGCACAGGAGTTTGCTGCTGATGTACGGCTTATGTTCTCCAACTGCTATAAGTACAATCCCCCAGATCACGATGTTGTGGCAATGGCACGAAAGCTACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000204256:ENST00000374825:7
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.646 A=NA C2=0.340
Domain overlap (PFAM):
C1:
PF090735=BUD22=PU(20.2=52.0),PF0043920=Bromodomain=PU(52.8=37.6)
A:
NA
C2:
PF090735=BUD22=FE(13.0=100),PF0043920=Bromodomain=PD(44.9=93.0)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATCTTGGCTCCTGGTTCTCCA
R:
GCATCCCGGTAATCACGGTTC
Band lengths:
356-861
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains