HsaINT1007794 @ hg38
Intron Retention
Gene
ENSG00000256660 | CLEC12B
Description
C-type lectin domain family 12 member B [Source:HGNC Symbol;Acc:HGNC:31966]
Coordinates
chr12:10012785-10014741:+
Coord C1 exon
chr12:10012785-10012883
Coord A exon
chr12:10012884-10014522
Coord C2 exon
chr12:10014523-10014741
Length
1639 bp
Sequences
Splice sites
5' ss Seq
TGTGTAAGT
5' ss Score
7.65
3' ss Seq
TCTCCTGTCATGTCTTGGAGTTT
3' ss Score
-4
Exon sequences
Seq C1 exon
GGCATCCAGCTCCATCTCCCATTTGGCGTCATGCTGCTCTGGGTCTGGTAACTCTTTGCCTGATGTTGCTGATTGGGCTGGTGACATTGGGGATGATGT
Seq A exon
GTAAGTATATCAGCATCAAACCCAACAAAGGCAACTAGAAAACATATTGTAAACCATGTACTTTCAGCTTGGATTGTAGATGGGTCCTAGCATCCTGAATCGTCTGATACTTTTCTGCTGTCTCATATCTCTCCTATTCGTCATATCTTCCCAAAAAACCGGCAAAAGACATTATCAGGATTTGGTTCTAAATTCATTGTTTTATCTTGATAAGCTAAACTGGACTTAGACAAAGACTCTTTGTTTCCAGTTATTCATTAGAATAAAGAGCCTCTTTTCTGCCTAGACACACATTCACTTATCATTCCAATGCTGAGAAATAAAGTCAAGAAATATGTATTGAAGGAAGTGCTTGCTATTTTTATTTACCTGAAAGACTTAACACTAGACTAGGTTCAGTCTGCTTACATGAAACTTCTCTAGTGGAGAGAAATCTTCCAAGTAGCAGCAGCAGCCTGATTTCTATGAATGAGAAAGACATATAAACAAAGAGGAAGAGTGGCCTGATACACCTTACCAAGTAAGAGAGTTGAACCATCTCCACATGACAATGGAAGCTCCACTCTCAAGCACCACAGCCACAAAGGAACATTCTATTGATTCTGACCCATCCTCGGGAAGTTGGGGATGAACATGGTAGGGAGTTCTTGAGTAATGAGAAAAACATCCTGAGAATACAAACTTTATAGGGTTGTTAAGTATATGGTATACAGAGTAGTGAATTGGCATGGTATTCGCTTACAGGGAACTCACAGTCAAGAAAGTTAATTTGCTGAATGATACTAACATCTCCTCTGCTACATTCATTTCTTTTTAATGATTTAATGGATAATTTTTTAGGATTTAATGGTTAATTAGGATTTGGACATATCTTTGCCAACATAAAAAGAGACTAATGATGTACCTTGCTCTTTTGAAAAGGAATATGATGTTCAAGCAGCAGTAACAGATATTCTGGAGCCAATCAGTATGAGGATTAGCAGCCGATCTTCTACAATAATGTATATTTAAAAATTAAGTGAAAATGCAATAACGTACGTCCATTGGTTCGATATAGAAGGGTGACATTTCTTTTCTAAAATTTAGTGCTTTTGGTGCAGTGGTTCTTAAATTTGTTGTGCTGATGAAGCACCTTAAATGCTTATGAAAAGGGCATATTTCATGGACCCATGACGAGAAATGGTCTGATATGCCATTAAGATCTGCTTTTTCTTTTCTTTTGGTAAACAAGCATCTCAGGTCATCTGCAGAGTTTGAGATATCCATTGTCCCAAAGAATGCTGTTTTCATTAAAACAACAATTACATCATCTATCTCCAAATAAAATAAAACAAAAATAAAACAATTTCATGAAAATGAGTGGCAGAATGACTGGCCCTTCCTTAGATGTGATGTCAGAAATATATCATTATTAAATCATTATTTTAATATAGTGCAATAATAAAAATGTAAATAAAATTATAAAGAACTATAAATAATTTGGAATAGAAAGGCATCTGGTTTGTTTCTTTCATGATACCTCAAATACTAAGAGCTACTAATAAATCTTGAACAATTAAGAAATGTTTCTGTCACGAGAATTATCTACAGTTATAAGAATAGAAGAATATATGAACTTGTCTCCTGTCATGTCTTGGAG
Seq C2 exon
TTTTGCAGATATCTAATGACATTAACTCAGATTCAGAGAAATTGAGTCAACTTCAGAAAACCATCCAACAGCAGCAGGATAACTTATCCCAGCAACTGGGCAACTCCAACAACTTGTCCATGGAGGAGGAATTTCTCAAGTCACAGATCTCCAGTGTACTGAAGAGGCAGGAACAAATGGCCATCAAACTGTGCCAAGAGCTAATCATTCATACTTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000256660:ENST00000338896:2
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.118 A=NA C2=0.216
Domain overlap (PFAM):
C1:
PF083915=Ly49=PU(23.0=82.4)
A:
NA
C2:
PF083915=Ly49=FE(59.8=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGCATCCAGCTCCATCTCCC
R:
CTGAAGTATGAATGATTAGCTCTTGG
Band lengths:
318-1957
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains