HsaINT1010458 @ hg38
Intron Retention
Gene
ENSG00000231852 | CYP21A2
Description
cytochrome P450 family 21 subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:2600]
Coordinates
chr6:32038415-32039248:+
Coord C1 exon
chr6:32038415-32038624
Coord A exon
chr6:32038625-32039093
Coord C2 exon
chr6:32039094-32039248
Length
469 bp
Sequences
Splice sites
5' ss Seq
AAGGTGAGA
5' ss Score
8.68
3' ss Seq
GCCCCCACCTCCTCCTGCAGACA
3' ss Score
9.45
Exon sequences
Seq C1 exon
GTCTCGCCATGCTGCTCCTGGGCCTGCTGCTGCTGCTGCCCCTGCTGGCTGGCGCCCGCCTGCTGTGGAACTGGTGGAAGCTCCGGAGCCTCCACCTCCCGCCTCTTGCCCCGGGCTTCTTGCACCTGCTGCAGCCCGACCTCCCCATCTATCTGCTTGGCCTGACTCAGAAATTCGGGCCCATCTACAGGCTCCACCTTGGGCTGCAAG
Seq A exon
GTGAGAGGCTGATCTCGCTCTGGCCCTCACCATAGGAGGGGGCGGAGGTGACGGAGAGGGTCCTCTCTCCGCTGACGCTGCTTTGGCTGTCTCCCAGATGTGGTGGTGCTGAACTCCAAGAGGACCATTGAGGAAGCCATGGTCAAAAAGTGGGCAGACTTTGCTGGCAGACCTGAGCCACTTACCTGTAAGGGCCGGGGGCATTTTTTCTTTCTTAAAAAAATTTTTTTTTAAGAGATGGGTTCTTGCTATGCTGCCCAGGCTGGTCTTAAATTCCTAGTCTCAAATGATCCTCCCACCTCAGCCTCAAGTGTGAGCCACCTTTGGGGCATCCCCAATCCAGGTCCCTGGAAGCTCTTGGGGGGGCATATCTGGTGGGGAGAAAGCAGGGGTTGGGGAGGCCGAAGAAGGTCAGGCCCTCAGCTGCCTTCATCAGTTCCCACCCTCCAGCCCCCACCTCCTCCTGCAG
Seq C2 exon
ACAAGCTGGTGTCTAGGAACTACCCGGACCTGTCCTTGGGAGACTACTCCCTGCTCTGGAAAGCCCACAAGAAGCTCACCCGCTCAGCCCTGCTGCTGGGCATCCGTGACTCCATGGAGCCAGTGGTGGAGCAGCTGACCCAGGAGTTCTGTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000231852:ENST00000435122:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.022
Domain overlap (PFAM):
C1:
PF0006717=p450=PU(24.8=58.8)
A:
NA
C2:
PF0006717=p450=PU(11.2=80.8)
Main Inclusion Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCTCGCCATGCTGCTCCT
R:
GAACTCCTGGGTCAGCTGCTC
Band lengths:
358-827
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains