HsaINT1010462 @ hg38
Intron Retention
Gene
ENSG00000231852 | CYP21A2
Description
cytochrome P450 family 21 subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:2600]
Coordinates
chr6:32039749-32040205:+
Coord C1 exon
chr6:32039749-32039835
Coord A exon
chr6:32039836-32040004
Coord C2 exon
chr6:32040005-32040205
Length
169 bp
Sequences
Splice sites
5' ss Seq
AAGGTGGGG
5' ss Score
5.87
3' ss Seq
GCTCCTTTCACCCTCTGCAGGAG
3' ss Score
9.48
Exon sequences
Seq C1 exon
TTCTTCCCCAATCCAGGTCTCCGGAGGCTGAAGCAGGCCATAGAGAAGAGGGATCACATCGTGGAGATGCAGCTGAGGCAGCACAAG
Seq A exon
GTGGGGACTGTACGTGGACGGCCTCCCCTCGGCCCACAGCCAGTGATGCTACCGGCCTCAGCATTGCTATGAGGCGGGTTCTTTTGCATACCCCAGTTATGGGCCTGTTGCCACTCTGTACTCCTCTCCCCAGGCCAGCCGCTCAGCCCGCTCCTTTCACCCTCTGCAG
Seq C2 exon
GAGAGCCTCGTGGCAGGCCAGTGGAGGGACATGATGGACTACATGCTCCAAGGGGTGGCGCAGCCGAGCATGGAAGAGGGCTCTGGACAGCTCCTGGAAGGGCACGTGCACATGGCTGCAGTGGACCTCCTGATCGGTGGCACTGAGACCACAGCAAACACCCTCTCCTGGGCCGTGGTTTTTTTGCTTCACCACCCTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000231852:ENST00000435122:5
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.015
Domain overlap (PFAM):
C1:
PF0006717=p450=FE(6.2=100)
A:
NA
C2:
PF0006717=p450=FE(14.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCTTCCCCAATCCAGGTCTCC
R:
GAGGGTGTTTGCTGTGGTCTC
Band lengths:
251-420
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains