HsaINT1011469 @ hg38
Intron Retention
Gene
ENSG00000158486 | DNAH3
Description
dynein axonemal heavy chain 3 [Source:HGNC Symbol;Acc:HGNC:2949]
Coordinates
chr16:21049910-21051868:-
Coord C1 exon
chr16:21051670-21051868
Coord A exon
chr16:21050019-21051669
Coord C2 exon
chr16:21049910-21050018
Length
1651 bp
Sequences
Splice sites
5' ss Seq
CAGGTACAC
5' ss Score
7.29
3' ss Seq
TTCTATTTTCTTCCCCATAGGAC
3' ss Score
12.78
Exon sequences
Seq C1 exon
CCCGCGACGTGGTGGCCAAGTTATCTGAGGACAGGGTCTCCGATCTGAATGATTTCCAATGGATCTCACAGCTGCGCTACTACTGGGTGGCCAAGGATGTGCAGGTGCAGATTATCACCACAGAAGCCTTGTATGGCTATGAGTACCTGGGAAACTCCCCCCGGCTGGTGATCACACCCCTCACCGACCGCTGCTACAG
Seq A exon
GTACACTCTGGAGCTCCTAGATCTGAGGGGTGAACGGAGAACTCCAGGGGAAGAAGACTCTGGGGAGGAAAGTTAGGGATGTCTTGGGTTACCTTTACCCTTCACACTTCAGATTATTAGATTCTCCATAGTCCCAAAGATGGGCATGCAAACTAGGTCTTCAGGCTAGACATGAGAACCCAGTAGGAATTCTAGTGCAAATCAATGTATTTGAACCAACAAGTGGAATATTGGTGCACATCCGTGAACATGACACAGGACTTAACGTAGAGGGCTCTCCAATGGCAGGAATCAAGATGGTGCCTGGAGATCCTATGGCCATAAGATAGACAAGAAGTGAGGTCAAGAACGTAGCCAAGGGGTCTCTATGCTCTGCCAGCCAGTCTCATGAAAAAAGCTGGCCATTCTGTGCTCAGCAAAGTCCTCTGACATTTTCTGTGGAACTCAGCCTTTGAGATCGGGATTTTGTGAACTTGTCGGTTTTGTGATGTTTAGATGTTCTTTGCTTTTATATATTTCCTTACAGTGAGAGTTTTTTAGATTGTAAAACTAATACTTGGGAGTATTTTCTCCCTTCAAAATCCTCAACCACTTGTTTTTTATGGTCTATGATTTTTGCTCTTCATTCATTTATTTATTCCACTTATTATTCAACAACCATTTTTTGAGGTTTCCTGTGCACCATGCATGACCTCAAGAAACCCTAAATCTAACTGGGGGGTCGGGAGAGACATATTCAAATGATTACAAGATAGAGTGCTAAATGAAAACATAGAAACTCATACCATGGGCCATGGAACCACAGTTATTACATCATTCATTTCTAACATTTATCTTGCACCTATTACATGCCAGGAGCTGTATTAATTTACTGAGGTTATGAAATGGAATCAAATATGATTCCTGAACTTTAGAGTTCATAATCTAGCTGGGCATGGTGGCTCACGCCTGTAGTCTCAGCACTTTGGAAGGCCAAGGTGGGTGGATCACTTGATCCCAGAAGTTTGAGACCAACCCGCTTGGGCAACATGGCAAAATCCCATCTCTACAAAAAATATGAAAATTAACTGGGTGTGGTGGTGTGTGCCTGTAAGTCCCAGCTACTTGGGAGGCTGAGATGGGAGTATCACTTGGGCCCAGGAGGTCAAGGCTGCAGTGAGCTGTGACCATGCCTCTGCACTCCAGCCTGGGCGACAGAGTGAGAACCTGTCTCAAAAGAAAAAAAAGAATTCATAATCTAGTTGGAGAAATATATTTTAACCATTCCATTAGCACTGGTGATCTTTGGAATGTAGAGTTTATGAGTATTCTCACTTTTATTTGATTCATTTATATAGGTATGCATGTATTCATTTATTCATTCAAACAAATATTCATGGGTGCCACTCATGTGCTGGACACTGTGCTGGGCTCTGAGGTTACAATGCCGAGTAAAATACAGTGATATTGTATTGCTCATATAATTGGGAAAAATTTTAACTATTTGGTTGGTGCAAAAGTCATCGCGGCTTTTAGCATTACTTTCAATGGCAAAAACTGCAATCACTTTTGCACTAACCTAAATATTTGTATGAGTCAAAATAAATGAAAAGCCGGTTTCTTTCCTGTGTCTTAGACCTCAAGCACTGAAGTTCTATTTTCTTCCCCATAG
Seq C2 exon
GACACTGATGGGAGCTTTGAAGCTGAACCTTGGGGGTGCTCCAGAGGGTCCAGCTGGGACTGGCAAGACAGAAACCACCAAAGATTTGGCCAAAGCCTTGGCTAAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000158486:ENST00000261383:29
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.216
Domain overlap (PFAM):
C1:
PF127742=AAA_6=PU(9.5=32.8)
A:
NA
C2:
PF127742=AAA_6=FE(15.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGACGTGGTGGCCAAGTTATC
R:
CTTTGGTGGTTTCTGTCTTGCC
Band lengths:
278-1929
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains