HsaINT1011918 @ hg38
Intron Retention
Gene
ENSG00000175065 | DSG4
Description
desmoglein 4 [Source:HGNC Symbol;Acc:HGNC:21307]
Coordinates
chr18:31406077-31409591:+
Coord C1 exon
chr18:31406077-31406373
Coord A exon
chr18:31406374-31409451
Coord C2 exon
chr18:31409452-31409591
Length
3078 bp
Sequences
Splice sites
5' ss Seq
TTTGTAAGT
5' ss Score
7.4
3' ss Seq
ATTGTCACTTTCTTGGGCAGTGG
3' ss Score
6.35
Exon sequences
Seq C1 exon
CTACCTCGGCAATCCTTACGGCTAAGCAGGTTTTATCTCCAGGATTTTATGAAATCCCAATCCTGGTGAAGGACAGCTATAACAGAGCATGTGAATTGGCACAAATGGTGCAGTTATATGCCTGTGATTGCGATGACAACCACATGTGCCTGGACTCTGGTGCCGCGGGCATCTACACAGAGGACATAACTGGTGACACGTATGGGCCTGTCACTGAAGACCAAGCTGGAGTTTCAAATGTTGGTCTTGGACCAGCAGGGATTGGCATGATGGTTCTGGGCATCCTGCTACTGATTT
Seq A exon
GTAAGTACTCAATTAAATCCTTCTTTTCAATAGTTCTTCAAAATAGGGCTGTTACGAGGCTCGCTGGGATGGTTAGGTTCATGGAGCCATTTCTTTTTGGTATCTCTAGCAATTTTTGAGTGCCTTAGAAATAAACAATGGGACTGACAAATATATGCGCTTAATCCACAATGATAACTAAGAAAGCCTAGGGTGAGTGACAGTCCTAAAAATGGGAAACACATGCAAATCACTACATATACTACCTAAAAGCACAAAACAAATCCCATCATGGAAATTTCCTTAAAATGCTTTAAGAGTAGAGAGGCAGAAGCAATTAAGTCCATGTGGAAAAGTTAGGACAATCTTTTGGAAAAGTGGATTTTGAGGTGAGCCTGAAAAGCTGAGGATTTTTTTTTTCTTTTTTTCTTTTTCTTTTTTTTGAGATGGAATCTTGCTCTATTGCCCAGGCTGGAGTGCAGTGGCGCAACCTCGGCTCACTGCAACTTCTGCCTCCCAGGTTCAAATGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCACCACCACGACTGGCTAATTTTTGTACTTTTAGTAGAGACGGGGTTTCACCATGATAGCCAGGATGGTCTTGAACTCCTGACCTCGTGGTCCACCTGCCTTGGGCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACTGCACCCTGCTGAGGATTTCTTTTAAAGGAGGATGATGTCTAAGGAAATTTGAAAGGTAATCAAACACACACACACAAAAAAAAACCACACACACAAACAAAAGGGAGCAAGATATGGAAGAGCATAGCACACCTAGGAAGCAGAGAGGCAAAAGGGAGTCTGGGAGCCAGCATGGAGGCATGTTCATGACACACCAGGCATTCTGGGCTTCAGTACAATGGCACAGAAGAGTTGATGAGGGCTGATGAGCGCAGGTGACCCTGCGGTAGGAAGCAAGTAGAAGAGACTAGAACAGAGAATTAGCCTCTGGGCTCTGGGTGAGTGCCTAAACTAAGACTGGTCACAGAAGTGGAAAGATCACCAAACAAAAATTTCCCAAAAAGGGCCCTCCTTTCCCCATAGAGTTTTTTTAAACATATAGATCCTCAGAGGAAGAATACTTCATACATTTTAGGTTGCCCTTGCAATATTTAGGTTTCATGGGGATCAAAAGCTGGGTTCTAAAATTAAAGAGAAGTAAATTTGTCAAACTGTATTGTTGCTGTTTTCAGGGATGAGCACTAATTAAAATGTAATCATTTCAAGGCATAAAAAATAACAGCTGACTTTTGGTGAGGATTTCTTTTTTGAAATAATCTGTGAGGTTTCAAAGCTATGCAAAGATCATGAGTGATTCTCACAATGATATTAGACACATTTTCCCAGAATATAACTCTACAGCAATTGAGTAGTGGTTTCGGGTAAGCTTTGAGTTAGCGGTTCTCAACCCTAGTTGTACATAAGAATTAGTTAAAGGTCTTCCAAAATTACTCATACTAGAGTCATACTCAAGATGAGACCAAGCATCAGCATGTTCAAGCCCTTTGGTGAGACTAATGTGCAGTTCAGGGCTAAAAACCCAGTGCCAGCTGCATTTCCAGAACGTTAGCACTAAGAATTTCAAGACTTTTTCCTGACCCAGACAAAGAAAGCATGAGAGTTGTTCAACTGATGGATTGTAGAATAGGAGAGGAATACCCCTATGGACACTTGTTTTCAATGGAGAAGCCCATGGTCTATTTTAGGAGAGAGGGGGCAGTGTGATGGTAGTGGGAGGGATCTGAGCCCAAACCTATGTTCCCAAAGGGCCTCAAATTGACACTTTTGATGTTAGCTCCAAATGAGATTACACATACAGTAATTGTATTGGGTATGTGCTAAAAACACTTCATTTCATTTATTAGATAGTGCCTTTGTTAGAGTTCAGGCCTGCAATGGTACATGATCCAGCTCACATTTAAATTCACAGAAATATAGAATAGGCAGAACCATGGCCTAGGGGCTACCAATTTTAGTTTTAGTCCTTTTCCAGAAAATGCTATGGAAATGTATAACTTGACCTTTCACTGTTCATAGTGCAGATGGCAAAATTGCCAAATTAATTGTTGTAATAAGACTAAAGCTGATTTTGCAACTTTGATAGTCTCTTCTTTTGTATCTGTTTTTAATTTTTAATTTTTGTGGGTACATAATAGGTGTACATATTTATGGGGTACATTAGCTGCTTTGATACAGGCATGCAATGTGAAATAATCACATCCTGGAGAATGGGGCATCCATCCCCTCAAGCATTTATCCTTCTATTCTTTATCTTTAATTAACCCACTTAGTAAAATGCATGCCATGCTAGAGAATTAGGAAAGTATGAAAAGCAACCAGAGTGGGCCCAAAGAACTAAACAGAGTGTATTCTAGAATCTTAGAAAACTTAAGCAGTGTCTATATTTATGGATTAAAATACAGAATTGAGGTGATTATTAGGGTAACAAATAGGAAATTTCCTCTTAAGAAACACTTGGATAGCTAAACATTTTTGATAGCTTTAATTTTTCATTATAGTCTATAAACAAAGTCTTAAAATAATTGTAAATATCTCCATTAAATTTAGTGAGTATTATTTGACTTCTATTTTAAGTGTAACTGTAATAAGGATTGAAGATAGGTCCTATCTCCAGGTCCTATAGCTGAATCCTGTATTCAATCCTCTTGATAACATATATTCATGATGCGTTTAACTTACATGTATGTGTGCATCTGCCCCAACCAGTTCAAGAGTCTTAGACTAAAGACGACCTTACTTTCCTAATCTGTCAGCAAAGAAATTCAATTACCTGATCGCAAACTCCTTGCCATCTAGCGCTAAAGTTCTATGTGATTTGGTGGTGCTGTATTTATAAACTTGGATATGTATACTCAATCCCCTAAAGGAAAAAAATGAGATTTTCTTACATATATTTGTATTTTTGTTCTAAATATACTGCCACCAAATGCTCCCCAGAATGATTCATCCAGTGACTTCCTAAACCGAGCAATGTGTGTTAACTCGACATTGTCACTTTCTTGGGCAG
Seq C2 exon
TGGCTCCACTCTTGCTGCTCCTGTGTTGCTGCAAACAGAGACAGCCAGAAGGCCTGGGAACAAGATTTGCTCCTGTGCCTGAGGGCGGAGAAGGAGTGATGCAGTCTTGGAGAATTGAAGGGGCCCATCCCGAGGACAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175065:ENST00000308128:12
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.015 A=NA C2=0.266
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains