HsaINT1012819 @ hg38
Intron Retention
Gene
ENSG00000174279 | EVX2
Description
even-skipped homeobox 2 [Source:HGNC Symbol;Acc:HGNC:3507]
Coordinates
chr2:176082178-176083913:-
Coord C1 exon
chr2:176083350-176083913
Coord A exon
chr2:176082450-176083349
Coord C2 exon
chr2:176082178-176082449
Length
900 bp
Sequences
Splice sites
5' ss Seq
AAGGTAACC
5' ss Score
9.24
3' ss Seq
GTTGGTCGTTTGTTTGCCAGGGT
3' ss Score
5.87
Exon sequences
Seq C1 exon
CAATTTTTCCGCCTCCCTCCGAAAGCGATAATAATATTTAGAGGCGTTCGCTGGGGCTGAATGAGAATTAGCCCTAGGCGCAGCCTATCATTAGGACGGGACAGCAGGGCCACTGTGACATTTTTAAGAAAGCTGAGATGATGGAAAGAATAAGAAAAGAGATGATTCTGATGGAGAGAGGGCTGCACAGCCCTACGGCGGGCAAGAGATTCTCCAATTTGTCCAACTCGGCTGGCAATGCTGTGCTCGAGGCCCTGGAAAATTCGCAGCACCCGGCTCGCCTAAGCCCGCGCCTGCCGTCTGCCCCCCTGCACAGCGCTCTGGGAGAACTCCCCGCCAAGGGCAAATTCGAAATAGACACTTTGTTCAACCTGCAGCACACGGGCAGCGAAAGCACCGTCTCCTCCGAAATCTCCTCCGCCGCCGAGAGCCGCAAGAAGCCGGGCCATTATTCAGAGGCGGCCGCTGAGGCCGACATGAGCAGCGACGTGGAGGTGGGCTGCTCCGCGCTTCGCTCCCCCGGGGGCCTCGGCGCCGCTCAGCTTAAGGAAAACAATGGCAAAG
Seq A exon
GTAACCGCGCCGGCCGCACCGCGCTCTCCAGTCCCATCCTCTTTGCTCCTCCGCGGCCCCCGCCAGCCTTTCCCGGTGCCTTTTCCCCTCTCAGACCCTCCACAGGCAAGCTACACCGAGCTAGCACGGGCGGGGGCGGGACGCATGTCTGGGACCGTGCCTTCCAGTTCTGCTCCTTGAGCTTTCCCGCCAGGCTCAGGCCTGCGGAGCCTGGAACACCAGGCCCACCCGCCCTCGCTCCTGAGTCCGAGAAAATGTTTCTGCGCTCGTGTCTAAGAGCCCGAGCGAGCCGGTAGACCCCTAGTCAGCAGCCGAGTTGCTTTTGGGAAAGGTACCCTGGGCAACTACTCTGAACTCCCCTGCCCCTGTGCCCTCAGGGCTGGAGGGGGCATTCTTCTGGGTAAGTCGGAGGAAGCCTCGCCGGCGTCTCTGTTTAGGTCAGCGGGAGAAAGAGTTGAAAAGTATATTTCACCCCCTATTGGCTTGGGTTTGAGCTACTGCTGTGTTGGAACTCTTAAAATATTTGAAACCCCGAAGACTCAGATAAAGGTTAGAGGCCGTATAAAAAGCTGCCCTGCGGTCTCCAGACCATGGGAAACCCAGAGCTTCCCAAACTGCGCCCAGAGGTAGGCATTTTCCCTCGGCCACTTTTCCTCCTTGGTTGAAAATTTCTAATTATTAAAAAAGAAATCTCCTAATTCCGTTTCTATTATTTGCTTATGAAGGGCTCCCCAAACTTTATTGATTCCATTAACGGCAGCAATTTGTAAGCATGACAGACCCCATCAATTCCGGCAGCGACTCTCCTTCCTGACGGGGCTTCCCCGATCCGCGCGCAGCGCCAGCGCCGGGCTGTTGGTCCTACAGCCACTCATGCGCTGTTGGTCGTTTGTTTGCCAG
Seq C2 exon
GGTACGCAGAGAGCGGCTCGGCTGCCGGCACCACGACGTCGGCGTCGGGCTCAGGCCTCGGAAGCCTGCATGGAGGCAGCGGAGGCAGCGGCGGGAGCGCGGCGCTGGGTGGCTCCGGCTCTGGCGCGGATCAAGTGCGGCGCTACCGTACGGCGTTCACCCGCGAGCAGATCGCGCGCCTGGAGAAGGAGTTCTACCGGGAGAACTATGTGTCGCGGCCCCGCCGGTGCGAGCTGGCCGCGGCACTCAACCTGCCCGAAACCACCATCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000174279:ENST00000308618:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.706 A=NA C2=0.527
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0004624=Homeobox=PU(77.2=48.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAGCCGGGCCATTATTCAGAG
R:
CGCGACACATAGTTCTCCCG
Band lengths:
344-1244
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains