HsaINT1015505 @ hg38
Intron Retention
Gene
ENSG00000159399 | HK2
Description
hexokinase 2 [Source:HGNC Symbol;Acc:HGNC:4923]
Coordinates
chr2:74886490-74888058:+
Coord C1 exon
chr2:74886490-74886673
Coord A exon
chr2:74886674-74887902
Coord C2 exon
chr2:74887903-74888058
Length
1229 bp
Sequences
Splice sites
5' ss Seq
GAGGTAGGC
5' ss Score
8.99
3' ss Seq
GAATGTTACTTGCATTGCAGGTT
3' ss Score
6.72
Exon sequences
Seq C1 exon
GCACGGGCAGCAATGCCTGCTACATGGAGGAGATGCGCAACGTGGAACTGGTGGAAGGAGAAGAGGGGCGGATGTGTGTGAACATGGAATGGGGGGCCTTCGGGGACAATGGATGCCTAGATGACTTCCGCACAGAATTTGATGTGGCTGTGGATGAGCTTTCACTCAACCCCGGCAAGCAGAG
Seq A exon
GTAGGCACCCAACTGGGGCCCTGTTAAGTGTATCCCAGGACTGGATGGCAACAAGTGATCAGAGCTTCCACAATGGCATCTCCCAGGACGCCGGTTCTCGTGAGATGTTAATAAAGGAGGTTTTCTTGGAAAGGGTTTCTTGTCGAATGCACCTGGAAAGTTCTGAGTTAGTAAATGTAAGAAGCATCTCCCACCCAAAAGCCTAGGAGAACAGGTGGGAGAATACTAGACCCTAGGTCTGGCACTCTAAGGAGAAACAAGTAGAAAGTTGAAGCACCTGCTGCTGACAGGCTGAAGAGCATCTCTTGGGTGATGCAGACAGGAGCAAATCCTCTCCCTCCTCCATCTTCCAGCGCCGAGCACCACCTACTGTCAGAATTGAGCAAGGGGCCAGCCCCAGTGTCACAAGGTCCTGTGCATGGTAGGGGAGCGGGGTCTGAGCTAAGAGACAATAGCTTAAGATCTAACACACTTCTCATTAAGATGTTGTCTGTAGTGTTTCCTAACTAGATTAATCAAACACCCTAGTCCTGCAGAATACGCTTTGCAAAACATGTGTCTAGAATAGAAGTTACAGACTAAAATGCCTCTAGGGGCCAGGCAGGCAACATTAATGAAGGAAGCAGGCTGGGTCAAGATAAGATGGGGTGGTGATGGGCTATTGGTTGAAACTAGGGACCTCGTTTTTTTTTCAAGGCAGGATTCAGGACCAAAAGACCCTCAAGCCACTGCATAATAACGTTTAGTTCCAGTGGCCAGGATGGGGGCCCTACAGCTGGCAGTAGTTACTTGAGTAATGATGGTTAGGTCCAAGAGAATGTATACTGAATGCCTAGTGAGGTTAAAGATTAAGACTCAGCATTCTCCCCTGCTCCGAGAAGTCCAGTGGGGTTATGGTGTGTTCCTTCTCGAGTTGCTTCTTGAAATTTCGAAATAAGCCTTGGAAAGGAAATGAGTTCCTTTCCCTGTGGGTTCCTTTCCAAGGCTTATTTCCCCAGGAGCCCCACGGGCCTCGGGCACTGTGGTCAGTGTTGCTGAAGGTTGTGAATTAGCATGCAAAGACACCAGGGATCCTGCCCAAGTGAATCAAGTAGCAATTCCTTTCCCATCAGGGGAGTCTGCCTGTCTGCCACTGCTGATGCACTGGGGGTGACTAAGCTGGCCTGTCCTGTCTCAACACATCCCTCCACCTTCCTACTTAACCTCCATGAATGTTACTTGCATTGCAG
Seq C2 exon
GTTCGAGAAAATGATCAGTGGAATGTACCTGGGTGAGATTGTCCGTAACATTCTCATCGATTTCACCAAGCGTGGACTACTCTTCCGAGGCCGCATCTCAGAGCGGCTCAAGACAAGGGGCATCTTTGAAACCAAGTTCTTGTCTCAGATTGAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000159399:ENST00000290573:15
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0372711=Hexokinase_2=FE(25.4=100)
A:
NA
C2:
PF0372711=Hexokinase_2=FE(21.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGCTACATGGAGGAGATGCG
R:
TCAATCTGAGACAAGAACTTGGT
Band lengths:
321-1550
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains