HsaINT1015511 @ hg38
Intron Retention
Gene
ENSG00000159399 | HK2
Description
hexokinase 2 [Source:HGNC Symbol;Acc:HGNC:4923]
Coordinates
chr2:74877166-74878921:+
Coord C1 exon
chr2:74877166-74877321
Coord A exon
chr2:74877322-74878687
Coord C2 exon
chr2:74878688-74878921
Length
1366 bp
Sequences
Splice sites
5' ss Seq
AGGGTGAGC
5' ss Score
7.75
3' ss Seq
GCTATCTTTCTGTTTCCCAGGGA
3' ss Score
8.59
Exon sequences
Seq C1 exon
GTTTGAGAAGATGATCAGTGGGATGTACATGGGGGAGCTGGTGAGGCTTATCCTGGTGAAGATGGCCAAGGAGGAGCTGCTCTTTGGGGGGAAGCTCAGCCCAGAGCTTCTCAACACCGGTCGCTTTGAGACCAAAGACATCTCAGACATTGAAGG
Seq A exon
GTGAGCTTCTGGCCAGCCCCCTCTATTTGCTGGATCACCACACGAGTTGACGGGTAGTTGGGGAATGAGGAGGGGGCTGTACCTTTTGACTCTTCAAGTATAGACTGCAAGAGGGTCTCACATGACGTGGACCATGGCGGGCCTGTGGCTTCACTTCACTTACCAGTCTCCACTCTTGTCGATTTCGATTGTGATTGCTACCAGTGACTCATGGTACTGGGAACGGTGGTTGGCCTCCATATGCAGGGACTTGGGCTGTTGCACTGGGTTTAAAGCTGGAGGACCCCAGAGGGCCCCCGAAAGACTTAGCTGCATCTGCCTCCTTTTCCTTCTCCTGAAGCTCTGACATCTGATTCCCTATTGGCAATTCTCAAAAAGGACTCTGTCATGACCCCTGCTTCATAATAGAAAGCTAGGTCTTTGAATTGGCCAGAGATATAGCTACCCAATTAATTCTAATAAGCAGAGCTGGGGCCTGCATTTTCACAGCCCAGCAGGGGCAAGAGTGAGGATGGCTTGATTTTTGTTGTTGTTAACAATATCCCAAGAGTCAGGCGGGCCTCGTTTACTGTTCTTGAGATTTCCACTTGTAGATTGAAGAAGTCCTGGTGTTTCAGGGACCAGATGGTGGAGAGGAGGTGTCTTTGGAGCCAAATGGAGCAGTGGAACAGTGCCAATGACTTTGTTTTAAGGGGAAACTCTTGAAGGAATGGGGCCTACTTGTTGCTATACCCCAAGGTGATGCAAGTACCCCAAGGTGATGCAAGATTTAGTTCCCTTGAGAAGGGTGCTAAGGTTATAGCACTAGCCCCTTACCAACCATCTTTAGACACAAGCTAAAGCAGTGCCAAGTCCATGGTGAAATGCAATAGACTCCTACTGCTTTAGAGAGAGAAACCAGGTGGGCATCACCGCAGGGTTCACATGTTGAGAGTGGCTGACAGCAGAGACACTGTCTGTCTCCCCTAACACAAGCAGATGTAACACAAACTCTCACACACACAACTTGGTGGTAAAGCACCAAGAACAGGGCCTTGTTTTTACATAGCACATGCATAAGAAATACTTGTGTTTCTCAACTCCGTGTGTCTCTGTGTGTGTGTGTGTGTGTGTGTGTGCGCACGCACATGCGTGTGCGTGTGTGTGTGGTGTCTGGGAGAGGAGCCTCAGGGTGGCTGTGCTATATTTTGCACCCCCTTCCTCCTCCTCCTGCCCCTGCACAGGTGGACTAAGCAATGAAGAGGGATTCTGTCCCCACTGGGTGGTGAATTTGCTGGAACTAAAGGGCTTCCTTGCCACCCCCCGACACACACACTGGCCACAGTGGGTCAGACACAGGCCCACATGCTATCTTTCTGTTTCCCAG
Seq C2 exon
GGAGAAGGATGGCATCCGGAAGGCCCGTGAGGTCCTGATGCGGTTGGGCCTGGACCCGACTCAGGAGGACTGCGTGGCCACTCACCGGATCTGCCAGATCGTGTCCACACGCTCCGCCAGCCTGTGCGCAGCCACCCTGGCCGCCGTGCTGCAGCGCATCAAGGAGAACAAAGGCGAGGAGCGGCTGCGCTCTACTATTGGGGTCGACGGTTCCGTCTACAAGAAACACCCCCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000159399:ENST00000290573:8
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.006 A=NA C2=0.049
Domain overlap (PFAM):
C1:
PF0372711=Hexokinase_2=FE(21.7=100)
A:
NA
C2:
PF0372711=Hexokinase_2=FE(32.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGTGGGATGTACATGGGGGAG
R:
TCGACCCCAATAGTAGAGCGC
Band lengths:
347-1713
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains