HsaINT1015573 @ hg38
Intron Retention
Gene
ENSG00000196126 | HLA-DRB1
Description
major histocompatibility complex, class II, DR beta 1 [Source:HGNC Symbol;Acc:HGNC:4948]
Coordinates
chr6:32581557-32584378:-
Coord C1 exon
chr6:32584109-32584378
Coord A exon
chr6:32581839-32584108
Coord C2 exon
chr6:32581557-32581838
Length
2270 bp
Sequences
Splice sites
5' ss Seq
GAGGTGAGC
5' ss Score
8.7
3' ss Seq
CTACGTTGTTTTTCTCCTAGTCC
3' ss Score
7.44
Exon sequences
Seq C1 exon
CACGTTTCCTGTGGCAGCCTAAGAGGGAGTGTCATTTCTTCAATGGGACGGAGCGGGTGCGGTTCCTGGACAGATACTTCTATAACCAGGAGGAGTCCGTGCGCTTCGACAGCGACGTGGGGGAGTTCCGGGCGGTGACGGAGCTGGGGCGGCCTGACGCTGAGTACTGGAACAGCCAGAAGGACATCCTGGAGCAGGCGCGGGCCGCGGTGGACACCTACTGCAGACACAACTACGGGGTTGTGGAGAGCTTCACAGTGCAGCGGCGAG
Seq A exon
GTGAGCATGGCCGCGGGCGGGGCCTGAGTCCCCGTGAGCTGGGAATCTGAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGAGAGAGAGACAGAGAGAGACAGAGAGAGGAAGAGAGAGAGAGAGCGCCATCTGTGAGCATTTAGAATCCTCTCAGTCCGGAGCAAGCAGTTCTGAGAGCACAGGTGTGTGTGTAAAGTGTGGATTTGTCTGTGTCTGTGTGTCTGTTGTGGGAGGGGAGGCAGGAGGGGGCTGTTTCTTATCCTTGGAGACCTCTGTGGGGAGGTGACAAGGGAGGTGGGTGCTGGGGGCTGGAGAGAGAGGAGACCTTGATTATCTCGGTCCTTAGAGATGCAGGGAAGGGAAATGTAAGGTGTGTGTGGTTGGGGTGAAGGTTTAGGGGAGGACTGCTGAGGGGTAAGGCAGGTTTGGGATAATGTGAGGAGGCCAGTTCCAGACTCTCCCTGGCATACACCCTTCGTGTAATCTCTGAATTAAAAGTGTGTGCTGTTTGTTTGTAAAAGCAATAGATTAATTTCTAGAGGAACTGAGTAGACCTCTGAGGCACCTCTGAAGCTTCTTTAGATCTAAATTTCTTCCTAGTTTTTTGTTTTTTTCAGTGTGTATATTTTTACATAGTAGAAATGACTGTGAAACTAACTTTTTGAATTAAAGTTTTGACACGGTTACTATTTTATTATAATGCTGGTAGTTTTCTAGTAGTTACATATTATTCTTTTATATATAATATTTGTGACACAACTCACCTCACTTTCCCGTTTGTTGACCTTTATTATGACATTCACCAGAAGTTGAAATTGTGTGTTTCTGGTTAATTTTTAATTTATATTTTTTATTTGTAATTCCTTTGAATTATTTTGCCCTATTTATTGGCCGATTATAATTATTGCTCTAAGAATTCCCTATTGTATTTGGTAGGTAATGGACAATGATCTACGGTCTAATATCTTGAGGGCTTAGTATTTTTCTCAGTGACTTTCTGCGTTCTTTGTACTATAAGATTATTAACACTTTATTGATATTTGATCCAGCATTTGCTCCAGTTTGTGGTTTGTATGTGGATTTTGAAAATTCTTTTCCATGTTAAGAATTTGAACATTTTTATTTAATAAAATATATTGCAACATTTTTATTAATGATCTACAATCCATCTGAAATCTGCCATTTTGTGGCATTGTTGTCTCCAGGTTTCTCCTTACTTCTAAAAAAATAGTTGTATTTATTGAGAGTATGCTAGTGTCGGGGATTTTCCTGGGCATAAGCACCCCAAGTAACGAGTCCCAGACACTGCCTTAATCCAAATGTGATTCTGGAAAGAAAAATCATTTTACAATGATAGGCCTAATAATAATTATGCTTGTGTTGCACGGGAGATGCATTGATCAGCTAAATGTAAATATAAGAACTTTCAAAACTTAAATGACGTTCCCTAATCCTTCTCTCTGCTTCAGGACTCATGCTTTTCTAGGAAAGTAAAAATTTGGAGAATCATTTCTGTCTGTCCCACCTTCCCAGGGGCAGAACAATTTCTGTTGTGTTCTAAGGTGTGAGTGCATGGGAGTAGTATTCCTAAAATTCATACTTGGTTTCCTCATGTACCCAACTCTGTCCCTTTATCTATGCATATTGCTTTAAATCATATTTTTCTGTCAAGGTGTACAAGGATGATAAATAGGTGCCAAGTGGAGCACTCAAGTGTGATGAGTGCCCTCACAGTGGAATGGAGTGAGAAGCTTTCTGACCTCATAAACTGAAGGCTATCTTCAGTCATTGTTTTATATATTTTACGTGCATTAATCCTCATATAACCCCAAGAGGTAAATTAGTATAATTATCCTTCATTGTAGGTGACAAAGTTGAGACACAGAAGAATCAAAAAACTCTTCCAGGATCAACCAGTAAAAGGCAGACCTTGGATTCGAACCAGGCAACCTGGCTCAAATATCAGTTTTAATTACTACACTCTGTACTTTCCAAGATTTGTAAACAGTTTGACAATGCATGCCGATTTAAAACTATGAAGAAACAAACACAATTTTTCACAACACCTCTCAAATCTAATGGGTCCTCACTGTCAAGATTAAATTCCAGGCTGATGACACTGTAAGGTCACATGGCCAGCTGTGCTATAGGCCTGGTCAAGGCCAGAGCCTGGGTTTGCAGAGAAGCAGACACACAGCCAAACCAGGAGACTTACTCTGTCTTCCTGACTCATTCCCTCTACGTTGTTTTTCTCCTAG
Seq C2 exon
TCCAACCTAAGGTGACTGTATATCCTTCAAAGACCCAGCCCCTGCAGCACCACAACCTCCTGGTCTGCTCTGTGAGTGGTTTCTATCCAGGCAGCATTGAAGTCAGGTGGTTCCTGAACGGCCAGGAAGAGAAGGCTGGGATGGTGTCCACAGGCCTGATCCAGAATGGAGACTGGACCTTCCAGACCCTGGTGATGCTGGAAACAGTTCCTCGAAGTGGAGAGGTTTACACCTGCCAAGTGGAGCACCCAAGCGTGACAAGCCCTCTCACAGTGGAATGGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000196126:ENST00000360004:2
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.011
Domain overlap (PFAM):
C1:
PF0096914=MHC_II_beta=WD(100=82.4)
A:
NA
C2:
PF0765410=C1-set=WD(100=87.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains