HsaINT1022037 @ hg38
Intron Retention
Gene
ENSG00000100068 | LRP5L
Description
LDL receptor related protein 5 like [Source:HGNC Symbol;Acc:HGNC:25323]
Coordinates
chr22:25357255-25360189:-
Coord C1 exon
chr22:25359827-25360189
Coord A exon
chr22:25357427-25359826
Coord C2 exon
chr22:25357255-25357426
Length
2400 bp
Sequences
Splice sites
5' ss Seq
GGGGTAAGA
5' ss Score
7.83
3' ss Seq
GACTTCTGCTTCTTCTCCAGCCT
3' ss Score
7.15
Exon sequences
Seq C1 exon
GGACCAATGGAGGGTCTCGCTGGACACACCGGACTTCACCGACATCGTGCTGCAGCTGGACGACATCCAGCATGCCATCGCCATCAACTATGACCCAATGGAGGGCCACGTCTACTGGACGGATGACGAGGTGTGGGCCATCCGCAGGGCATACCTGGATGGGTCTGGGGCGCAGACGCTGATCAACACCAAGATCAACGACCCCGATGACATCGCAGTCAACTGGGTGGCCCGAAGCCTCTATTGGACCCACACAGGCACTGAACACATCGAGGTGACGTGCCTCAACAGCACCTCCCACAAGATCCTGGTGTCAGAGGACATGGACGAGCCCCGTGCCATTGCACTGCATCCCGAGATGGG
Seq A exon
GTAAGACGGGTGGGGCCTGGAGCCAGGGCCAGGCCAAGCAGAGGGAGCTTGACCTGGACCAGTCATTCTGGAACACTGTCTTGCATCAGAACCTGGAGGAAGGCTTGTTAAAACACCAGCGGCTGGGCCCCATCCCCAGAGTGCTGATTCAGGAGCTCCAGGGCAGGGCTGAGGACTTGGGTTTCTAACAAGTACCCAGGTGGTCCGGTGCTGCTGCTGGGTCCATGCATAGAAAGCCCTGGAGACCTGGAGTGAGCCCTTTCTTCCCCTAGCTTCAGCTTCCTGATCTGTAGAATGGAACAGTCCACCTGGGTGATTTCCAGGACGACAGTAGTGGTAGTAAGGGCAGCCTCTGTGACACTGACCACAGTACAGGCCAGGCCTCTTTTTTTTTTTTTTGAGATGGTGTCTCACTCTGTCGCCCAGACTGGAATGCAATGGCACAATCTTGGCTCACTGCAACCTCTGCCTTCCGGGCTCAAGCAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGCCTGCCACCGTGTCTGGCTAATTTTTGTATTTTTGCTAGAGATGGGGTTTCTCCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCCACCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCATGCCTGGCCAGGCCAGGCCTCTTTTAACACTTTGCACACCATGGGTCTTTTCATCCAGGAGGGTAGGTAGTTATACAGTTGAGGACAGTGAAGCCCAGAGATGCTCAGGGACTTGGCCAGGGTCACACAGCAGGAGGTGGCAGGTGTGTGGCTGGGGCTGACAGCATGGCTCCAGCTTTCCAGCGTAGAAGTCTGTGAAAGCAGAGAGCTTGTCGGTTGGTTGAGACCCCCCCCACAGCGGCTCAGATTGCTGTAGCCAGGGGCCTTCCTGGGGGCTCATAACCCAGAACACTAAATGGGCAGACCCTGAGGGAGGAGGTGCAGTGGAGCTGGGGGTGCCGATGGGAAGTCCCGGAGGAGCTGGGAGGTCAGTCGCAGTGCTGCTCTCTGTGGAGCACTTAGTAGGCACCAGGTGTGTTTCCAGGTTCATGGCTCTGGGACCCGAAGCTCAGGTGAAGTGACTTGCCCAGGGTACCCAGCGGGCAGAGGATTTGCAGGCTATGAAGCCTGCGCTCATGGCCTGGCCCTGGGGGTTGCCAGTGTGCTGGCTGGGGAGCTTTTCCTGCAAGTGAGCTGGTGTCTAGAAGCCAGCATGTCAGGCAGCAGGCAGCGGGAGCACAGTAGGCAGATGGTGGGGCCCAAGCAGCCCTCCATGGACCCCAGGGCATGGCGGCACGTGGAAGAGAGCTGCTCCATGTCGGTGGCTGACGGGCTGGGTTGTGCCCCGAGGAGGGCGGATGATGGTAGGAAGTGGGGTCCCCCAGGGCTTTAGCAAGAGGAGGCACAGGAACTGGTTGCCAGCTGCAGTGAAGGGAACATGGCCCTGAGGTCAGGAGCTTGGTCAAGTCACTGCCTCTATGGGCCTCAGTGTCCTCATCTGTGAAAGAGGAAGGGACGGGGAAGCCAACTCCAAGGTCCCTCCTAGCCCTGGTTTCATGAGTCTGAGGATCCCAGGGAAATGGGGCTTGGCAGTCTGACATGTGAGGTCATGGGGTCTAGGGAGGGGCACCGAGCTGGAAGTGGGAGGCAGAGGGGCTGGCCGGCTGGGTCAGACACAGCTGAAGCAGAGGCTGTGACCTGAGGCCCCAGAACCTCCACCCCTGAGCTGCCACCCCAGGATCTGGGTTCCCTCCTTGGGGGGCCACAGGGAACAAGTCACCTGTCCTTTGCACAGGGGAGCCCTTCAGCTGTATGCAGAAGATTGCGCTCTGCCCCTTCCTCCCTCTGGGTGCTGAGCTTCTTCAGCCCACCAGTCAGATGTGAGGCTGCCCTAGACCCTGGGCAGGGTCATTGCTATCCACTGACGTTTGAGATGGGAGATGAGCTCCTGGCCCCTCAGAGTCCTAAGGGCTGGTGCAGTGAAGCCTGCACAGGGTGGAAGTGGGCACCACTGTCCCAGGGGAGCCCCCAGGGACTCTGGTCACTGGGCTTGTGGCTGGCATGCTCAGTCCTCCAGCACTTACTGACACCAGCATCTACCAACACCAACATTTACAAACACTGACATTGACCAACACTGACAATTACTGACACCGACATTTACCAACACTGATATTGACCGACGCCGACATTTACCTACACCAGCATTTACCAATGCCGATATTTACTGACCCCAACATTTAGCCATGTGATGGGGGCCGGCTCGGGGACGGGCCTTGCTCTTAGCAGTGGGGGTGCCACAGAAACTAGACAGATGCATGGGGTCATGGACTTCTGCTTCTTCTCCAG
Seq C2 exon
CCTCACGTACTGGATAGACTGGGGAGAGAACCCTGAAATCAAGCGTGCCAACCTGGACAGGCAGGAGCTGCGCGTGCTGGTCAATGCTTCCCTCGGGTGGCCCAACGGCCTGGCCCTGGACCTGCAGGAAGGGAAGCTCTACTGGGGAGATGCCAAGACAGACAAGATCGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000100068:ENST00000402785:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.020
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=WD(100=46.1),PF0005812=Ldl_recept_b=WD(100=46.1),PF0005812=Ldl_recept_b=PU(0.1=0.0)
A:
NA
C2:
PF0005812=Ldl_recept_b=WD(100=72.4),PF0005812=Ldl_recept_b=PU(38.2=22.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains