HsaEX0036457 @ hg38
Exon Skipping
Gene
ENSG00000100068 | LRP5L
Description
LDL receptor related protein 5 like [Source:HGNC Symbol;Acc:HGNC:25323]
Coordinates
chr22:25354596-25360189:-
Coord C1 exon
chr22:25359827-25360189
Coord A exon
chr22:25357255-25357426
Coord C2 exon
chr22:25354596-25354812
Length
172 bp
Sequences
Splice sites
3' ss Seq
GACTTCTGCTTCTTCTCCAGCCT
3' ss Score
7.15
5' ss Seq
GAGGTGAGG
5' ss Score
8.41
Exon sequences
Seq C1 exon
GGACCAATGGAGGGTCTCGCTGGACACACCGGACTTCACCGACATCGTGCTGCAGCTGGACGACATCCAGCATGCCATCGCCATCAACTATGACCCAATGGAGGGCCACGTCTACTGGACGGATGACGAGGTGTGGGCCATCCGCAGGGCATACCTGGATGGGTCTGGGGCGCAGACGCTGATCAACACCAAGATCAACGACCCCGATGACATCGCAGTCAACTGGGTGGCCCGAAGCCTCTATTGGACCCACACAGGCACTGAACACATCGAGGTGACGTGCCTCAACAGCACCTCCCACAAGATCCTGGTGTCAGAGGACATGGACGAGCCCCGTGCCATTGCACTGCATCCCGAGATGGG
Seq A exon
CCTCACGTACTGGATAGACTGGGGAGAGAACCCTGAAATCAAGCGTGCCAACCTGGACAGGCAGGAGCTGCGCGTGCTGGTCAATGCTTCCCTCGGGTGGCCCAACGGCCTGGCCCTGGACCTGCAGGAAGGGAAGCTCTACTGGGGAGATGCCAAGACAGACAAGATCGAG
Seq C2 exon
GCGATCAGTGTCGATGAGACGAAGAGGCAGACCCTCCTGAAGGACAAGCTCCCACACATTTTCAGGTTCACCCTGCTGGGGGACTTCATCTACTGGACCGCCTGGCAGCACCACAGCATCAAGCGGGTACACAAGGTCAAGGCCAACCGGGACGTCATCATTGACCAGCTGCCCGACCTGATGGGGCTCAAAGCTGTGAACGTGGACAAGGTCGTCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000100068_MULTIEX1-3/3=2-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.020 C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=WD(100=46.1),PF0005812=Ldl_recept_b=WD(100=46.1),PF0005812=Ldl_recept_b=PU(0.1=0.0)
A:
PF0005812=Ldl_recept_b=WD(100=72.4),PF0005812=Ldl_recept_b=PU(38.2=22.4)
C2:
PF0005812=Ldl_recept_b=PD(55.9=26.0)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTATTGGACCCACACAGGCAC
R:
CTTGTGTACCCGCTTGATGCT
Band lengths:
258-430
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development