HsaINT1022756 @ hg38
Intron Retention
Gene
ENSG00000157890 | MEGF11
Description
multiple EGF like domains 11 [Source:HGNC Symbol;Acc:HGNC:29635]
Coordinates
chr15:65895079-65898934:-
Coord C1 exon
chr15:65898728-65898934
Coord A exon
chr15:65898095-65898727
Coord C2 exon
chr15:65895079-65898094
Length
633 bp
Sequences
Splice sites
5' ss Seq
TTGGTAGGT
5' ss Score
7.03
3' ss Seq
TTTTTCACTATATTTCTTAGAGC
3' ss Score
7.57
Exon sequences
Seq C1 exon
ATTACATGAAAGAATCCGTGTGCAGTTCTAGTACTTGTTCCTTGAATAGCAGTGAAAACCCTTACGCCACAATTAAGGACCCACCCATCCTCACCTGCAAGCTTCCAGAAAGCAGCTATGTAGAAATGAAGTCGCCTGTGCACATGGGGTCTCCGTACACAGATGTGCCATCCTTGTCGACATCTAATAAAAATATATATGAAGTTG
Seq A exon
GTAGGTGTCTCAAATAAGTAACTTAGTGAAATCAGGGCAATAGTGCAGCATTTGAAGTAAAAGCAAGCCCTCTCCACTCACCCCACCTTGACCACACATCCTTCTTTTGTTGCTTTTAAAGGCATCTCTAAGGTGAACTGTCTTTCCTAGGACTACCCTCCTAGCTAATGCAGGAAGTCAAATTATTGTACCAACTCTGCTTTAAAAAACACCAGGACTAATATGAAACAAATACTGGGGGTGGGAAATGGGCACATGCACGTGCACGCGCGCACACACACACACAGATTGTTGATACAAATCTCATTTTAAAAAAGAAAGCAATCAGAGACATCAACAAGTCTCTAAATCACCTTCTACCTTCTCCCAGTTTATGTCCCTGGGCTCACTGGTAAGACTCCTACCTCTAGGATATTTTAAATCCTTTGGTGTTGATGAGAGGCTTGGATGTTGACAGCACATTCACTTAGTTTTCCATCTCCTGAGCAAGCCTCAGTCCTAACCCTCATGTATTTGCCATAGATTTATAAATCCCTGGCTCCTTTCCCCAAGTTAAGTAGAACTCTCTTCCTCTCCAACAAGGCAACCAAAGCTAATCTGTTCTCTGAACTCATTTTTCACTATATTTCTTAG
Seq C2 exon
AGCCCACAGTCAGTGTGGTCCAAGAAGGTTGCGGTCATAACTCCAGCTATATCCAGAATGCATACGACCTACCTAGGAACAGCCATATTCCTGGTCATTATGACCTCCTCCCAGTAAGACAGAGCCCTGCCAATGGGCCGTCCCAGGACAAGCAATCTTAAGAGGGATAAGCTTCTCTCTTGCAGTGTGCTCTACTGAATATTCTGACTCTGAAAGAAGACAGTCCCTTGACTTGAAGTAATGGTACAGACTGGCTCCAGCTGCATGTTAGTTATTACGTTCACCTGGAACTAAAGAAGAGCGTCCAGGTGGGACTGGGATAATTGTTCAAGGAATTGTGTTCTCAAAGGCAAATCCTATCACCCACTCAGCCCCAAATGCCCTGGATTATATGATTTTTAAAACATTTTAAGATACAGCTACTCATCAACATCAGCTAAATATAGCTGATATATATATATATATTTATCTGAAACGTGATATTTTAAAAACATGTAGGTTTAACAAACCTTCCTAGGACAAAAAGGAGACTGGGGAGGGAAGAGGATTACTTTAAAGCACCTGAAACGTATATGTACTTTTGGTTGCTGTTACCATCAACATCTGTTTTATTACCGAAGACAATTAGTACACAGACATGAACTGTTCTTAAACAGAACAGTCTTAAAATGTCTGTACATATCTGTCTGGTCCATCAAATTACAACAGCCAAGATTACAGAATCTATATAGTCTAATGCTGACAACTTCTATTTTAAAAAACAAGACTTTACTTTCTTCTGCCCCCTAAGTGATAGGTTTAAACACACAGAGACACACACACACGTTTCCAAAGTGCAGCAGTGTCTCTTTCAGTCTACAATAAGATTCCTAGGGCAGCTTTATCAAATTTTGCCAATTCAAAGTTCAAGGACATTACAAGTTAGTCCTGGCTTTGTCATATCTACTTAGTCCATCCGACACCTGAATCATTCCATGTAAAACAGAGCTCTAAGATGATCCTTTAAGCAAGCAGTCATAGACTGGTCGGGATTAAGTAAAAGACGGCTAGTTGGCCTCCTCATTTTATTTGGTCAGCATCCCTTGACTCAAGAGTACTTGCTTTCAAGTTCTTCATAAATCTTGAGATTGACGTAGTATGAAACCTAAAAGTATACAGGAAATTGGACAAATGTGGATACAGCAAGTTTACACTGCTTAAAGTACATTATGCTTTTTAATGGAACTAAATGATCAAAAAAAGAATGGACTGTAACCAGTTGCTGTAACGTGATGTAAAAACGTTACTGTAAACAGCATGAGGATATGAAGTCCTTCCACCTTCTATCTTAAAACTACTACTTACTGAGCTAGCCCAATATGCATTACAATGAGCTAATGCTCCAGATCCCAGTATTCAGATGTGTCTATACCTTCCACTATGAACACAGATAAACTGAGGCTCAGATAAGTCCAAATGAAATGAAATCAACTCCCAAGCCCTAAAGAGAACCTTCTCACAAGAATTAAAAACAAAAAGGGCAAACCTAGGAAGCTAACGGCTACTCCTGTACCACTCTATTCACTGGTACAGTCCAGCCAGTAAAAAACACTTCCAAAAAGATACACAGAAGAGGAACTAAATGACTGCGAAGCTGGAATACTGCTACAGGAAGTATGAGAGTTCTGAAACCCTTGATAGAAACTGGAAGCCTGCCATGGAACACAATACTTTGGGCAATAATCAGAAAAAGCAAAAAAATAAATAAATGAGTACATCTCCCCTTCCCACATCACTCAAGGCATAAGCAGATTTTACTGTTAGAGGAAAATATGTAATACTTACATGAATGTTGCATGTGTGCATGGGAGCAACTGAGTAGCAATAGTAAATTTACTTTCCAAAAAAGCCTTATTAAAATATAAATATTAGAAAATTACTTTGGAGACCCAAGTAAATATTTCTCATACATATGTAGAAAGAAATATAGGTAAGCAGCTTACCTCAGTATTTCAGGGCAGCAAGTGTTTGTGAAGCAAGGATGAGCAGCATGAAGATGTCAGATCAGCAAGGAGAAACTTCAACTCAATCCCAGGTTTTCTCTTCTTCCCTTATCCTGCATGTACAATAACTGCTGCCTGGCAAACTGCAAACAAGCAGCATCACTCAAGTTTGAAGTTTCGCCGCTTTTGTCAACTATCCTCTGGGCAAAGGTATTCAGCAAGAGGTGGAATGGCTAGACACTGAATCAAGAGATTTCAGTGTTACTCTGGTCAAGTTAGTCGCCCTCTCTGGGCTCCCTTTTTTCCTATGCATAAAAAGGGGAGAAGCAGAGAGTGGGAAGACAGCTCTACTAACCCTTCAGCTCTAGCAGTCCATGACTTTTTAAGGAAATGTAATACAAGTCAAACCAGGCAATACAGAGGAGAAGGGAAAGGCAGAGGGTGTGATTATGGTGACAATAGCTGCCTTCCCCTATCGAACAGTTATCAGTAAAAGACATTTCAATCTTACAAAGCAACTGTTAGAAACTTCTGTCTAACACCATCACAAATAGGTTCATGGTCAGCCTAAACATGTATACTGTGCATTTTATGGGTGACTTTGAAAGATCTGTTCAATTATTTTTCAGAAACTAAATTTTCAAAAAATTAATATGTGTACAATTAAAATGAATGAAAGAAAAACCATTATTGTACAGAGGTATTAATGAGACTATGAAACGGCAATACTTTTTTAAATCACAGATTTGTAATATATGTTCACTGTGCAGAGGGATTGTACCTTGTACAAAATAAAACAAATTTCTCAAACTAATTTAACAAGAATGCCTACTGTTGTGTTGCAAATGGAAAACGTGCTTATAATCTACACCTTAAGTTTAAGGGTAGAACTAACCTACATCCTGCTTGGGCACTTTGAACACCTGGAAGAATGAAAATTATTCTAGTAGATGTTTGAAAATAAGTGAAAAACTTGTATCAAATTTTTGATAGACGAGTCTCTTTCTTTAAAGTAATAAATGTGAGCACCATAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157890:ENST00000409699:22
Average complexity
IR
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.300 A=NA C2=0.472
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAATGAAGTCGCCTGTGCACA
R:
AACTAACATGCAGCTGGAGCC
Band lengths:
357-990
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains