HsaINT1024120 @ hg38
Intron Retention
Gene
ENSG00000264424 | MYH4
Description
myosin heavy chain 4 [Source:HGNC Symbol;Acc:HGNC:7574]
Coordinates
chr17:10447818-10448520:-
Coord C1 exon
chr17:10448396-10448520
Coord A exon
chr17:10448127-10448395
Coord C2 exon
chr17:10447818-10448126
Length
269 bp
Sequences
Splice sites
5' ss Seq
GAGGTACAT
5' ss Score
6.75
3' ss Seq
TAAATGTTGCTTTTATTAAGGCA
3' ss Score
4.37
Exon sequences
Seq C1 exon
AGGAGATTTCTGACCTGACAGAGCAAATTGCAGAGGGTGGAAAGCATATCCATGAACTGGAGAAAGTAAAGAAACAACTTGATCATGAGAAGAGTGAACTACAGACTTCCCTAGAGGAAGCAGAG
Seq A exon
GTACATTTTTCATTTGCTTAGCTCTGCATTATAAATAAATTGAAAATTAATAGCAACTGAGATCTCTATCATGTTGCAAATCTTTAGGGAATAACACAAGTAATTCAGTGAAAAATACTGAATTGTACCTTGAGAATGCAGAGCTAATAGGCTACATTAAGACGTATGATAGTTTATGGGTTTTTTAATGCCTTCTTGGGGAAATTATCATAATGTGAAAGAAATAAAAAGCTCTTTAGGTAACCTAAATAAATGTTGCTTTTATTAAG
Seq C2 exon
GCATCTCTTGAGCATGAAGAAGGCAAAATTCTTCGCATTCAACTTGAGCTAAATCAGGTGAAATCTGAGATTGACCGAAAAATTGCTGAAAAAGATGAAGAACTCGATCAGCTAAAGAGGAACCATCTCAGAGTTGTGGAGTCAATGCAGAGTACACTGGATGCTGAGATCAGGAGCAGAAATGATGCTCTGAGGATCAAGAAGAAGATGGAGGGAGATCTTAATGAAATGGAAATCCAGCTGAACCATGCCAACCGCCAGGCTGCTGAGGCACTAAGGAATCTTAGAAACACACAAGGAATACTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000264424:ENST00000255381:33
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.810 A=NA C2=0.456
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(4.8=100),PF0003816=Filament=FE(13.8=100)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(11.9=100),PF0003816=Filament=PD(12.1=35.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGACCTGACAGAGCAAATTGC
R:
TGCTCCTGATCTCAGCATCCA
Band lengths:
293-562
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains