HsaINT1027362 @ hg38
Intron Retention
Gene
ENSG00000225190 | PLEKHM1
Description
pleckstrin homology and RUN domain containing M1 [Source:HGNC Symbol;Acc:HGNC:29017]
Coordinates
chr17:45435900-45439634:-
Coord C1 exon
chr17:45439477-45439634
Coord A exon
chr17:45437970-45439476
Coord C2 exon
chr17:45435900-45437969
Length
1507 bp
Sequences
Splice sites
5' ss Seq
CAGGTATGC
5' ss Score
9.37
3' ss Seq
GCCTACTGCTCTCTCCCCAGGTG
3' ss Score
12.23
Exon sequences
Seq C1 exon
ATCGCAGACGGGGTGTATGAAGGATTCCTCAAGGCCCTGATTGAATTTGCCTCCCAGCATGTCTACCACTGCGACCTGTGCACCCAGCGCGGCTTCATCTGCCAGATCTGCCAGCACCACGACATCATCTTCCCCTTTGAGTTTGACACCACAGTCAG
Seq A exon
GTATGCGGGACACCCAGCCAGCCGCCTTCCAGCCCCACCCTTCCCCACACCCACAGCCTGGCCCAAGCACGCAGGGCAGCAGGCTTCGCTCTGTGGGCAGGAACTTATTGAACATCCACTTTGTGCTGTGCCAAGGGGTGGTGCAGTTGTTGGGGCAGCCCATGCTCTGGGCAGTCATGGCCAGCTCCAGTCCAGCTCAGGGGACAAGACAAGCTTTCCCAGGACTCCTCTGCCTCTATGGAACCATCTCTCTTCCTAAAGAAGAGGTGGCTGCCGGCTCTCTGAGTGGAGCCTCCTGGCGCCTCAGTGTATGCATGGGTTGAGGAGGGTTGTATGAGTTACCACCCTGCACTGTTGGCATGAGACCAGGCACAAAGTGGCACCTGGTGGGTGGTACCTGCCACTGCCACTGTGTCTGTTGCTGAAATGATCACTCTTGTTCCCAGTTATTGCTCATTATCCGCAACCTCTCAATGGAAAAATTTGTCCAGACCTTCCTGCAACCCATGTGGGAGCAGAAAACTGAACTGGGAACATTAGTTCTTTTTCTGTCGGTGTCCACTGGCCGGGATGCAGCCCTGAATGGGCCTGGGGCTGAGTTTTTAAAATTATACCATCTTGGCCGGGCGTGGTGGCTCACGCCTGTAATCCCACAACTTTGGGAGGCCAAGGCAGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTCCACTAAAAACACAAAAGTAAGCCAGGTGTGGTGGTGGGCACCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGGGAATCACTTGAATTCGGGAGGCAGAGGTTGCAGTGAGCCGAGATCGTGCCACTGCACTCCAGCCTGGGCAACAGAGCAAGACTCTGAAAAATAAATAAATAAAGTAAGTAAAAAAAATTTTTTTTTTCTTTTTGAGATGGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAATGGTGCAGTCTCGGCTCACTGCAAGCTCTGCCTCCCGGGTTCATGCCATTCTCCTGCCTCAGCCTCCCCAGCAGCTGGGGCTACAGGCACACACCGCCACGCCCGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACTGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTTGTGACCCGCCCACCTCGGCCTCCCAAAGTGCTGGGATTAAAGGCGTGAGCCACTGCGCCTGGCCGTAAATATTTTTTAAATATAGGCAAGAGATCTTTAATGAATCTCAAGCAGCATTTATAAAAAATGCAATAGGACAGAGAATATCAGTGTGCATTGTGTGACGTATGGGTAAGCACTGTTTCAAGACTCTCCTGTTCCAGAACGGAGAGGCACGGTGTGCGTGCATGGGTTACACAGTACATCACAGCCGTATCGTGGGTTCTGGTCAAAAGGGCTGGCCAGCGTGGCCACAGGGCAACCTCCAGCCCAGCCGGCACCAGCAGGCCTACTGCTCTCTCCCCAG
Seq C2 exon
GTGTGCCGAGTGCAAGACCGTCTTCCACCAGAGCTGCCAGGCTGTGGTGAAGAAGGGCTGCCCCCGCTGTGCCCGCCGGCGCAAGTACCAGGAACAGAACATTTTCGCCTGATGCCCATCTGCTGACCCCGCTCTGAAAGCCGGGGGTGAGTGTGGCTCAGCCATCCCGGCTGGGTTTGCCATCAGCCCAGGATACTCACCGTGTCACAGCTGTGTCCCCTTGTCAGGAAGACCCTCAGATGTGGCCAGAGCACCGGCCTCCCAGAGAAAGCCCAGGAAGTCCCCGTGGTGTCCCCTGGCCCTCCCCCCACCCCTCTGCTGCAGGAGGCGTGGCCACCACCAGATGCTCCCTGTCTGGGGCAGGCAGGGCCGTTTACTCACCAGGCCCTGGCTCACCAGCGTCCCGGCGCCTCCGTTAGGGCTGCCCAAACACTGTGGAAAGGGGACTTGGGGAGCATTTTCAATTCCACATTCCTGATTAAAAGGTCTAGTTTTTTAAGGTGGGTTTTTCCCATTCATATTTCAACAGAAAGTATTTTTTTATTCTTGACCCTACGTGAGTCACCCATGAAATCCAGACATTCTCACCCCCAGCGGATGCACAGGAGCCACTCAGGCCTGGCTTAGAGGTAGCGGGTGGCTGGTGGGCAGGCCACTGCTGGGACAGGGTCTATGGGCCCACCCAGTGCCTTTCCTTGGCCCTCACTGCCAGTGCCAAACCGCCCCTCAGCAGGGCAGGGCCAGTCCTGGCGACCCCGGTTCCTCTGTGTCCTCTTTACTCCCCACCCCAGTGCGTCTCGCCTGCTGAGCCCACCGCTTTCTCAGCGTCAGAGCCCCTAGCTCTTCTCTAGCCTGGGGCCTTGGCCCCATTAGGAGAAGGAGAAATGACTGGAAACCAGCACTGTCAGCACTTTGAGCCCTCCTCGGTTTATGGAGGGTCGCCGTCTTGCCCACCCCCGATCCCCGTGCGCTCCTCACCCCTCTACAGACAGGGGCGCTGCTGCAGATGCTCCAGGCCCACCTTGGTGGGTGCCCGGGGTCACACTCTCTGCCTGACTGACCCCTGCCAGGGCACAGATAGGCAGGACCCCAGAGAGGGCAGGCAGCCACGCCCTGCACTGTGGAGAAGTGACCTGGTCCTAAGCTGTGCAGGGCGTGCGGGGGAACTGCCCTGTGGATGCAGCCACCACCTCACAAAGCCATGAATTCCCAAAGCATCACTGAACTTGCCCAGCCGGGACACTGGAGACTGAAGAAGTTCCCCGGAGCAGGACTGCCTTTGAAGGGGCCTTGGGGCTGGGGTGGGAGTCTGGAATTGTTTTCAAAGTGATGGTCAGACCCTCCAGGCTTCGGGGAAATGTGGGTTTGCTGGTCTCTCTGTCGCCTTCCCCCACCTCTCCTGGACCTAGCAGGCCCTCAGTCCTAGCTGTCTTACCTGCGCTCAGCTTGGAGTCAGGCCTCAGGTGGAGAGCCGCATGTCACTGTCAGAGATGAGCCCACCCCCACCCTTCCCTGGGGGCGATTAGCTGCTGAGTCACCCACCCAGCCTTGGAGCTGGATGCCTGTGCAGCAGAACAGAGGCAACGGTGGCAGGCAGGTGGAGGCTGCGCACAGCTTCTCCCGGTCATGGCACACACCTGTGCCCAGACGCCAATGCCTCCTAAGCCAGGAGCTGGGTTATGCACCGCCATGGCCCACATTAACGCTCCACCACAAGCCCAGCCTAGTCAGAGCCCTCATTGCCCCATCCCTGAGTGGGCAGGAGCCTGGCCTGGGGAGGGCTTGGGCCTGTGAGGATTCTCCCCGAAGGTGCCCTCGGAGGCAGCAGGTTTGAGGCCCTGGGGGGCCCGTTCCCCAGAAGCTGCCAGTGCTTTCAGATGCATTGACTCTTCCCGCCTCCCCTCCCTCAGAAAGGTAGTGCCCACACTATTTTTAAAATGTTATTTTATGCAATACACTGTTCCTAGTGAGCAGGGCTCTGGCCCTGAGGAGTCTTTGCAATGTATTGAAGGAATTGCTGCCGTGTGAGTTTTGAATGATTTTGCAGTAAAGACCTGATCTTTCTCATCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000225190:ENST00000430334:11
Average complexity
IR
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF139011=DUF4206=PD(0.1=0.0),PF139011=DUF4206=FE(50.7=100),PF0062824=PHD=PU(42.6=57.1),PF098454=DUF2072=PU(5.6=5.7)
A:
NA
C2:
PF139011=DUF4206=PD(14.6=78.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAGGATTCCTCAAGGCCCTGA
R:
TGACACGGTGAGTATCCTGGG
Band lengths:
346-1853
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains