HsaINT1028261 @ hg38
Intron Retention
Gene
ENSG00000237412 | PRSS56
Description
protease, serine 56 [Source:HGNC Symbol;Acc:HGNC:39433]
Coordinates
chr2:232523060-232523578:+
Coord C1 exon
chr2:232523060-232523202
Coord A exon
chr2:232523203-232523415
Coord C2 exon
chr2:232523416-232523578
Length
213 bp
Sequences
Splice sites
5' ss Seq
CAGGTATGA
5' ss Score
9.46
3' ss Seq
CCTCTCTCTTGGCCCCGCAGGGT
3' ss Score
11.27
Exon sequences
Seq C1 exon
ACGGGCCTGAGGCTGAAGCAGTGAGAGAGGCCCGTGTTCCCCTGCTCAGCACCGACACCTGCCGAAGAGCCCTGGGGCCCGGGCTGCGCCCCAGCACCATGCTCTGCGCCGGGTACCTGGCGGGGGGCGTTGACTCGTGCCAG
Seq A exon
GTATGAACCCAGTCTGATGAGAAAAGGCCGGCTGAGCCTTCCCAGGGCCACTACGGCCTCTTTTCCTTCCACGTCTGTCTGTCACTCGACTTCTCTGAGCCTCTCTGTCCTCATCCCTAAAATGGACACAAGTGGCAAGCTCACACCTGCCAGGCGTAAGGCAGGCGTCATAGGGGGCAGGTGAATGCAGCGTCCTCTCTCTTGGCCCCGCAG
Seq C2 exon
GGTGACTCGGGAGGCCCCCTGACCTGTTCTGAGCCTGGCCCCCGCCCTAGAGAGGTCCTGTTCGGAGTCACCTCCTGGGGGGACGGCTGCGGGGAGCCAGGGAAGCCCGGGGTCTACACCCGCGTGGCAGTGTTCAAGGACTGGCTCCAGGAGCAGATGAGCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000237412:ENST00000449534:7
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.083 A=NA C2=0.164
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=FE(20.6=100)
A:
NA
C2:
PF0008921=Trypsin=PD(21.1=87.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGAGGCTGAAGCAGTGAGAGA
R:
CGCTCATCTGCTCCTGGAG
Band lengths:
299-512
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains