HsaINT1044306 @ hg38
Intron Retention
Gene
ENSG00000146872 | TLK2
Description
tousled like kinase 2 [Source:HGNC Symbol;Acc:HGNC:11842]
Coordinates
chr17:62596585-62600820:+
Coord C1 exon
chr17:62596585-62596674
Coord A exon
chr17:62596675-62600650
Coord C2 exon
chr17:62600651-62600820
Length
3976 bp
Sequences
Splice sites
5' ss Seq
CTCGTAAGT
5' ss Score
9.63
3' ss Seq
ATTGGTTTATTTGTCTTTAGGTT
3' ss Score
9.22
Exon sequences
Seq C1 exon
GCATGCATGTAGGGAATACCGGATTCATAAAGAGCTGGATCATCCCAGAATAGTTAAGCTGTATGATTACTTTTCACTGGATACTGACTC
Seq A exon
GTAAGTGCTGTGCTGTTTTACCTTAACAGTTATATTATTTTCTTGCAATGCTGATTGTTCATGGAATAGAGCTGAACTCTGGGTCCAGGACATACCCTCTGAGGGAACCAAGTAATTTGTGACAAATGATCAAACATAAATTCAGATTTGGATCAGCAAGAAACCTCTAGGCCAAAGGACATGTGCACTTGTGTGCCAGTAAATGTTTAACAGCCAGCTTGGTATGAAGAGAGACAGGGCTAATTTATAGTGTTTGCCAGTTTCCGTGGTGTAGATATTCCTCCTGTGTCTAATTTTGATGTACCACCTGTTTATTTTTGTTTTTTTTTAAACATCTTAATTATAATTCACATACTGTATGATTCACACATGTAAAATATACAGTTTAGTGGTTTGTAGCATATTCATAGATACATGCAACCACCAGAGGCAATTTTAGAATTTTTTCACCATCTCAAACCCCATCATACCTTTTACTACTATTCATCTATTCCACCATTCCATCCCTCTGCCCTAGCCCTAATCTGTCTGTTTTATCTTTATAGATTTCCTATTCTGGACCCTCATATGCATGGAATCATATAGTATGTGGACTTTTATTACTGGCTTCTTTCACTTACCATGGTGTTGTCAAATTTCATCCTTGTAGCCTGTGTCAGTACTTCATTCCTTTTTATGGCAAAATAATATTCCATTGTGTGGATATACCACATTTTGCTTATAACGGTTTGATAACCAGCTCACAAAATTCTTGAAAATTTAAGTCAGCTCTTGGAAACTGGCATGAGTTGGTGCCAGCATGCCACTGACGTGCACTAGTGAGTGTAGACTGTTCAAGAGAGTTTCTGCTCACCCCAGAGACTCTTATGAACATTGACAGACCTTTTTAAAAAGTACTGGCCGTGTGATTTTATCCTAGACTGAGATAAGAAATGTGGCACTAATGAAGACAAGGCTCAGTGCTACATGTTGAAATACAGGCTCATAGGCTTATAGGATGTTAGAATAGGAAGGGATCTCAGAGTCCAGCCTTTTCATTTTATAGGTGGATTTTGAGGACCAGAGAAGTTAAATAACTTGTCTGAGATAGTTATTAATTGTGGGCATTGCTATATTTTGTTACTTGGTATAGGTAACCTCCCGTGCCTCTGGGTTTATCCAGCAGTTTAGCTGGATATATCTCAGCATTTGGAAATGTTTCTCTGTAGAAGTCTGAACTGAATCAGAATATACCCTAGGTCTAGACTTCAGGTTCCCTCAGCCTCCCAGGGTAATTCTAGGAGTTTTGGTCTGTTCTAGCCAACAGTCTCAGATATGGCTGTGCAGACAGCTGCCTTACATTTAGAAATAACCCCAAAGAGGACTATAATTCCCTTTGGAAACATGACCTGGGCCATTCTCTCAGGGATTTCTTCTCATTTGGGTAGCCCTGGCACTGAGCTTAGCCATGTGTGTTTCACGTGGAGTGGAATTTTTTTAAAAAGATCTAGTTAGAAGGCAGGATTGGGAAACAAGGGGCGGGGCATGACATTACTGTTTTGCCTTGAGCAAATTTCTTGAATACTAGGTAGACCCCCCTCTCTGAACTATTAAGTTCAAGAACTATTTCAAAGTTAAATATCAGGCTCAAATTATCTGCTGTTTTGAATTGTATACACACTTTTAACTAATGTGAGAAATTGAGTTGGTTCTATACTATTCTTGAGTTGATTACTTTGTTCTTCCTATTGTATGTATGATGAATTTTCACCAAAAATAAGTCAGACCATGATTTTTAGAACATCTTCTGAGAATTGTTTGGGTATTAAAAGTGAGGCTTTATTTTCTTTTCTTTCTTTTGTTTTGGTTGTTTTCCTTTTTTTTTTCCTGAGATGGAGTCTCACTCTGTTGCCCAGGCTGGAGTTCAGTGGTGCGATCTTGGCTCACTGCAACCTCCACCTCCCAGGTTCAAGCGATTCTCCTACCTCAGCCTCCCATGTAGCTAGGATTACAGATGCACGCCACCATGCCTGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCGTGCTGGGCAGGCTGGTCTTGAACTCTTGACCTTGTGATCCGCCCGCCTGGGCCTCCCAAAGTCCTGGGATTACAGGCTTGAGCCACCGCGCCTGGCTGAAAGTGAGGCTTTATTTTCAACTTGCATTTGGGTGAAAGAATCATTCCATTGAGCATGAGTCTATATTTCAGATTTCAGAATCTCAGATCAGAGGAATCTATAAATTTCAGACATTTCTTTTTTTAATTTTATTTTATTTGAGATGGAGTCTTGCTCTGTTGCCCAGGCAGTAGTGCAGTGGCATGATCTTGGCTCACTGCAACCTCCACCTCATGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCATGCGCCACCATACCTGGCCAATTTTTTGTATTTTTAGTAGAGACAGAGTTTCACTATGTTGGCCAGGCTGGTCTCAAACTCCTGGCCTCAAGTGATCCACCCATCTCTGCCTCCCAAATTGCTGGGATTACAGCAGACATTTGTTTTCAAATAGGGTGTTAGCATGCCCTGCCATGTTTCTTAAGATACATAAGATATTGTTCAGTTTGTGGTGTCCACAGGACCATGTGTGTCCATGTTCAATTGCAGTGCTTTATGAAGGCCTCAAATTGCTCAGTGGCCCATAGCGCTAGACCTGAGTCTGTTTGCTCTCAGTTCTGTTCCTCGCCCTTTCGCTGCTCTGTATCTTTGGGGGGTTAGCCCGTGTAGGCTGTGTTTATCAGGCCCATGTGTCCATTGGTGTTCTGTTGGTTTCAGCCAATGGGAAGGCAGAAATGGGAGGGGGTCTCCACCTCCTCTCCCTCCCCGCAATTCTAGTTTCCCCTGATGACCCTGGGTTCTGGTTTCACCATCTCCTCCCTTCTGGCCTGCTTGCCTGAGGGTGCTAATGGCTTCCTGCTGTAGATGATCTCTAGGGTGCCTCACTGACCAGTTTGTCTTCTCAGCTCTTCCATCATCTGTATGATCAGTTCCCTGAATTAAAGTCTCTCTGTTTTAAATGTTCAGGTGGTTTTTTTTTCCAGGCTAAACTGACTGATACACCCACATTGTCACAACTTAGAAAACTTCAAAACGTATTCATCCCTCAGGAATATTCAAACAGTTCAGGACACCTTACTTCAGAGTATAATGCCTTGGAAGATAGACACGTGACCTGTGATGCCACCAATGGCATATGGTTTTATGTATGGGTCTGTATGACATATTGACATAAGGGAAGGAAAGAGAACCCACATACTTTTGTTAGAACCATAGATACTATACTTTACAAGCTCTTTTACACCTTGTGTTTAAGAGAAATTGTAGTGCAGTATTGTGCCAAGCTGTCAGAAGACGTAGTATGCAGTCAGTTTTTGGGACGTGGGCAAACTCTAGATTCTTACTCATTGCCAGCACTCAGGGTTATATAAAATGTTTGCAGTGCGAATTGTGTACCTAGCCAAAATTGCGCCACTGCACTCCAGCCTAGGCAGCAGAGTGAGACGGAGTCTCAAAAAAAAAAAGAGAGAATTGTGTACTTGATCACATTCTGGTTGTTTAGACGTGGATGTGTGGCATGGGTGTGTAAAGGAGCCCCTTCCAAGAAGATACCTAGCTTAAATACATTATAGTTCTTATCAGTATTCTTATAGTCTAGACTCAAGAAGAGGTCTGCCATGGGTGAACTTGAGCACAACAGATTCCAACATTGAGGGTGTGGAAACTCTTCAAGAGAATAAGCAGTTTCTTACCAGAAACCCCTCAGCTAATACTGAATAAACAATTGAAGAGTATTTTAAGGAACAAAGAAGAAAGGAGTGAGAAGCTGATGACCTGAAGTTTTCACATGGGACTAATTTAGGTAGTGTTAATCTGCTTGCTCTTATTCCATGGTTAAATATTGGTTTATTTGTCTTTAG
Seq C2 exon
GTTTTGTACAGTATTAGAATACTGTGAGGGAAATGATCTGGACTTCTACCTGAAACAGCACAAATTAATGTCGGAGAAAGAGGCCCGGTCCATTATCATGCAGATTGTGAATGCTTTAAAGTACTTAAATGAAATAAAACCTCCCATCATACACTATGACCTCAAACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000146872:ENST00000346027:17
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(10.7=100)
A:
NA
C2:
PF0006920=Pkinase=FE(20.4=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains