HsaEX7108214 @ hg38
Exon Skipping
Gene
ENSG00000146872 | TLK2
Description
tousled like kinase 2 [Source:HGNC Symbol;Acc:HGNC:11842]
Coordinates
chr17:62596585-62602180:+
Coord C1 exon
chr17:62596585-62596674
Coord A exon
chr17:62600651-62600820
Coord C2 exon
chr17:62602042-62602180
Length
170 bp
Sequences
Splice sites
3' ss Seq
ATTGGTTTATTTGTCTTTAGGTT
3' ss Score
9.22
5' ss Seq
CAGGTATGT
5' ss Score
9.8
Exon sequences
Seq C1 exon
GCATGCATGTAGGGAATACCGGATTCATAAAGAGCTGGATCATCCCAGAATAGTTAAGCTGTATGATTACTTTTCACTGGATACTGACTC
Seq A exon
GTTTTGTACAGTATTAGAATACTGTGAGGGAAATGATCTGGACTTCTACCTGAAACAGCACAAATTAATGTCGGAGAAAGAGGCCCGGTCCATTATCATGCAGATTGTGAATGCTTTAAAGTACTTAAATGAAATAAAACCTCCCATCATACACTATGACCTCAAACCAG
Seq C2 exon
GTAATATTCTTTTAGTAAATGGTACAGCGTGTGGAGAGATAAAAATTACAGATTTTGGTCTTTCGAAGATCATGGATGATGATAGCTACAATTCAGTGGATGGCATGGAGCTAACATCACAAGGTGCTGGTACTTATTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000146872-'71-68,'71-65,75-68=AN
Average complexity
A_C3
Mappability confidence:
100%=83=83%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(10.7=100)
A:
PF0006920=Pkinase=FE(20.4=100)
C2:
PF0006920=Pkinase=FE(16.4=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCATGCATGTAGGGAATACCGG
R:
TAAGTACCAGCACCTTGTGATGT
Band lengths:
226-396
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains