Special

MmuEX0003291 @ mm9

Exon Skipping

Gene
ENSMUSG00000026596 | Abl2
Description
v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene) [Source:MGI Symbol;Acc:MGI:87860]
Coordinates
chr1:158488917-158552786:+
Coord C1 exon
chr1:158488917-158489336
Coord A exon
chr1:158550970-158551032
Coord C2 exon
chr1:158552616-158552786
Length
63 bp
Sequences
Splice sites
3' ss Seq
CCAATTTTTGTCTTAAATAGATC
3' ss Score
8.23
5' ss Seq
CAGGTGAGA
5' ss Score
9.22
Exon sequences
Seq C1 exon
CTGTGCTCGGTGGTTTAAAGATGGCGGCGGCGGCTGGGGCGAGGAGCCGCCGGAGGGGGAGGGAGAAGGAGAGTCTGTGAGTCGCTGGGAGGCAGCGCGGCAGCGGCTCCGAGGAGTCCGCGTGGGAGCCGCCGGCAACTCCGGCCCAGAGGGCCTGGGCTTGGGCCGGAGAGACCGGAGCGGCGCCAGGAGCTCCGGAGGCCGGAGCAGAGGAGGAATGTGAGCAAGGGTCGGCGGGGGCGCGGGAGTACGCGAGCGGCGGGATGGGGCAGCAGGTGGGCCGCGTCGGGGAGGCTCCGGGGCTCCAGCAGCCGCAGCCGCGCGGGATCCGGGGCAGCAGCGCAGCCAGGCCCTCGGGCCGCAGGCGGGACCCGGCGGGGCGTACCGCAGACGCCGGCTTCAACGTCTTCACCCAGCACG
Seq A exon
ATCACTTTGCCAGCTGTGTGGAGGATGGATTTGAGGGAGACAAGACTGGAGGCAGTAGTCCAG
Seq C2 exon
AAGTTTTGCACCGCCCGTTTGGCTGTGATGCTGAATCTCAGGCACTGAATGAAGCGATCAGGTGGAGCTCCAAGGAGAACTTGCTGGGAGCCACTGAGAGTGACCCTAATCTCTTTGTTGCACTTTATGACTTTGTGGCAAGTGGTGATAACACACTCAGTATCACTAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026596-'1-1,'1-0,3-1
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.887 A=0.682 C2=0.172
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
NO

							
C2:
PF0001823=SH3_1=PU(38.3=31.0)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000027888





     
                   









    
Main Skipping Isoform:
ENSMUSP00000133381





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000126181
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr1:179133312-179133374 
ALTERNATIVE
HsaEX0000712
(ABL2)
Human
(hg19)
chr1:179102447-179102509 
ALTERNATIVE
HsaEX0000712
(ABL2)
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr16:61917207-61917269 
HIGH PSI
BtaEX0001979
(ABL2)
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TTCAACGTCTTCACCCAGCAC

				
R: 
TGCAACAAAGAGATTAGGGTCACT

				
Band lengths: 
144-207

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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